My right upper thigh is extremely sensitive with a burning sensation which is continuous. My left leg has started too. Could either pregabalin or amytriptyline be causing this rather than solving it? I have one pregabaline twice a day and one amytriptyline a night, but have increased the amount of both owing to my sypmtoms. I also take tegretol for epilepsy. I am not allowed to take anti-inflamatories owing to reflux. The amytriptyline is for my restless leg sydrome and poor sleep I believe.