Anyone here familiar with LDD (low dose dipyridamole), new medicine to help fibro patients with pain relief?

[Julie8787]

Hi All,

I recently read an article that I found interesting about a new medicine called Low Dose Dipyridamole which helps fibromyalgia patients with pain relief.

Is anyone familiar with it or has anyone here ever tried it?

Here is a link to the article if any of you would like to read it:

medium.com/@hablerannie/dip...

The information below was copied and pasted from the patent which was filed on LDD:

Treatment of chronic rheumatic or fibromyalgia pain

In order to determine the effect of low dose oral dipyridamole for treating chronic rheumatic or fibromyalgia pain, 3 subjects with chronic rheumatic pain were treated with the addition of low dose oral dipyridamole prepared according to Example 1 to their present pain regimen. Subject 1 (39 y/o female) was treated with 2 mg taken once daily with the first daily dose of oxycodone. Subject 2 (40 y/o male) was treated with 2mg or 5mg taken once daily, in conjunction with oxycodone. Subject 3 (45 y/o female) was treated with 2mg, 5mg or lOmg taken once daily with PERCOCET.

Subject 1 : After adding dipyridamole 2 mg the subject had complete relief of pain related to chronic fibromyalgia. She had previously been dependent on oxycodone 10 mg twice daily with incomplete pain relief.

Subject 2: After adding dipyridamole 2 mg the subject had complete relief of pain related to chronic rheumatic pain in the joints. When trying lOmg instead, there was negligible pain relief. 2mg was continued for 12 months. Within 3 months of use, this subject was able to completely wean off oxycodone while maintaining pain relief.

Subject 3: After adding dipyridamole 2 mg the subject had complete relief of pain related to chronic fibromyalgia and rheumatoid arthritis. At a 5mg dose, she experienced less pain relief, so she resumed 2mg. She had previously been dependent on Percocet with incomplete pain relief. Percocet was slowly weaned off after 2 months of low dose dipyridamole use.

This example illustrates that low dose oral dipyridamole is effective for the treatment of chronic rheumatic and fibromyalgia pain. It also suggest that low dose oral dipyridamole can serve as a substitute for opiates in some patients.

[desquinn Partner Volunteer FMAUK Trustee]

be interested to see the underlying research paper. All I can see is patent info and not and research papers. Need to see cohort size, design, controls etc.

[Julie8787 in reply to desquinn]

Im not sure where to find it, maybe there is a way to contact the scientists who filed the patent?