About ICSI or IVF

[trishabhowmik]

Hi everyone, I want to know is there anyone has gone through IVF with ICSI?..I want to know a bit about the difference. Actually, I have stage 4 endometriosis with adenomyosis, fibroids with low AMH. My previous cycle was failed..only one B grade embryo was found while doing IVF. My husband semen analysis I mean sperm quality everything is fine..In this case Do I need ICSI with IVF or just IVF only? I want to know the pros and cons about the ICSI with IVF?

[Klndmr]

Hey hun. Doctors know best if and when ICSI is needed. With our first round we were to go for normal IVF but due to low eggs retrieved and a low quality sample of the sperm they've used ICSI. I'm attaching a link which explains briefly what ICSI is and why and when is used. You can find lots of good articles which will help you understand better the difference.

Hope it makes sense x Best of luck with your future treatment xx

jetanin.com/services/ivf-icsi/

[trishabhowmik in reply to Klndmr]

Thanks very much

[Papillonblue]

ICSI (Intracytoplasmic sperm injection) is used when sperm aren't the best quality and Male factor fertility issues. Our first round converted to ICSI as on the day they weren't as good as when we had our initial investigations. I believe they also use ICSI if you are having the embryos tested

[trishabhowmik in reply to Papillonblue]

Thanks.. So if the male factor is not an issue so do I need icsi as well?

[Papillonblue in reply to trishabhowmik]

Shouldn't do, but as I said we hadn't expected to need ICSI but sperm quality can be thrown off by various things (like a cold !) My understanding is it takes 3 months for the male body to produce sperm and an infection 3 months earlier can affect quality. We had paid in advance for our treatment so this was a bolt-on cost we had to swallow

[Joeysjourney]

Hi there. I had ivf and then icsi. During my ivf cycle we had really low fertilitisation rates despite high quality sperm. So decided on icsi for the next round as my eggs might have harder shells (I'm older) or our sperm and eggs just don't communicate well naturally.

My fertilisation rates improved massively on the icsi round, though thats not always the case. I felt so lucky that it helped.

What's important next is how they develop into blasts, that's something icsi can't help with - that's down to egg and sperm quality. Icsi just (hopefully) gives you more in the running to develop! Everyone is different though and has different outcomes.

Your clinic will guide you and take on board your own circumstances and medical history.

Wishing you lots of love and luck!

Joey x

[StarsAllAround]

Hello. For ICSI the best sperm is selected then injected to the best egg and so on until all eggs have been injeted with sperm whereas in IVF the eggs and sperm are put in a petri dish and left for the sperm to fertilise eggs naturally. We did just IVF for our first round out of 7 eggs only 2 fertilised normally 2 fertilised with more than one sperm. We were advised to try ICSI on our next round out of 6 eggs 4 fertilised normally using ICSI and our 3rd out of 16 eggs 14 fertilised using ICSI. I definitely think ICSI was better for us, I should also say that my husband's spem is good quality I have low quality eggs and endometriosis.

[happilyevershahs]

Technically, if your husband doesn't have any sperm issues then IVF is usually the route but if the clinic suggest ICSI for a clinical reason then I would go with that. I would be wary as ICSI is more expensive so if there isn't a clinical need then it's not worth paying the extra money.

[Hidden]

What most clinics do is assume IVF unless there is a known problem. However on egg collection day once they have analysed the sperm sample they will make a call from there. Its not something you need to worry about - they tend to make the decision for you x

[trishabhowmik in reply to Hidden]

Thanks very much for the information

[minnesota_girl]

There are some circumstances in which a clinic will do ICSI due to the low number of eggs collected - in my circumstances, they recommended ICSI on my 3rd cycle because I tended to have only 4-6 eggs per round and they wanted to 'up' my chances of getting more fertilised embryos (e.g. even if it only left me with 1 extra) - so while yes it's normally used either with male factor issues or because you're doing PGT testing, sometimes the % improvement is worth the extra money - but again the clinic tends to recommend this or not - it is more money so it's worth understanding what value it may bring to you.

The downside of ICSI is that all eggs must be mature - so sometimes they ensure you have a bigger trigger to increase maturity at the end of your cycle to give the eggs a boost - as anything that isn't fully mature won't be fertilised.

I think it's something to have an open conversation with your doctor about and see what their recommendation is - but i agree that it's normally not something you need to worry about!

[Mystic_M]

Hi trishabhowmik,My doctors advice ICSI because I had a stage four endometriosis, with fibroids , low egg counts and of course age. The said they didn’t want to miss chances and hey, maybe they were right. I had four frozen eggs and thankfully three survived which I used one and I’m glad to say I’ve had a four month baby girl, with the other two still in storage .

Take the doctors advice and I’m believe all will work out.

Best wishes

xoxo

[trishabhowmik in reply to Mystic_M]

Thanks very much for yur information.. Really glad to know..I have the same problem.. My dr also said this..but some people said if there is no male factor, then icsi would not gonna help you..But I have the same problem like this..definitely will go for icsi..may I know how was ur AMH? And what grade yu got yur embryos?

[jengi]

Hi hun, I had low AMH too. Husband sperm was all fine. My first egg collection we only got one egg. We had agreed to do ICSI as my AMH was so low it was likely that my egg would be poor quality. The clinic accidentally did IVF and we had no fertilisation. My egg had a thickened zona pellucida (indicator of poor quality) & so no sperm could penetrate. So actually I was the right candidate for ICSI. Due to this error, we wrote a letter of complaint & actually got a 2nd chance on the NHS. So I would say if you have the choice & you have low AMH, ICSI is worth it Xx

[trishabhowmik in reply to jengi]

Thanks for your information. So sorry to hear about your situation.. So now did yu get your cycle now in Nhs? I actually did in private..

[jengi in reply to trishabhowmik]

We had our first cycle on the NHS & 2nd because of the mistake made with IVF/ICSI. After that we went private. We ended up moving to donor eggs. You can read our story on my profile. Please feel free to reach out if you have any other questions Xx