Do you need to wean off prednisone if... - Fertility Network UK

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Do you need to wean off prednisone if only taken during 2ww and 5 days before transfer?

PaulaDag profile image
6 Replies

Hi all,

If I get a negative on OTD do I need to wean off prednisone as I’ve only taken for 2ww plus 5 days before transfer? Fertility clinic says yes but they didn’t prescribe the steroids, but Epsom clinic said no need to wean if under 3 weeks and they prescribed them. Why do the professionals opinions always differ 😫.

Not sure what to do if I get a negative x

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PaulaDag
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6 Replies
Littlepeax profile image
Littlepeax

I'd say best to wean off them a little. I'm currently on 5mg a day and when I wean off I will take 5 mg every other day for around 5 days then stop. Huge goodluck to you in your tww! ❤️💫🤞

PaulaDag profile image
PaulaDag in reply to Littlepeax

Thank you ❤️🤞. Yes I think I’ll do that as well if needed, just to be safe xx

Purpledoggy profile image
Purpledoggy

You’re in a bit of a grey zone regarding whether you’re likely to have adverse effects stopping abruptly. It’s quite unpleasant if it happens so better to er on the side of caution. Wishing you so much luck-definitely your time now xx

PaulaDag profile image
PaulaDag in reply to Purpledoggy

Hiya hun, thank you 🤞. Really hoping this is our time. Day 5 today and not many symptoms except a few minor tummy twinges, but I’m getting worried as my period would have been due this Sunday. Am not sure what actually stops it coming, the implantation and the oestrogen/ progesterone I suppose?

Yes you’re right, I’m thinking it’s better to err on the side of caution as well if needed. I’m taking 25mg per day. One plus is that my psoriasis has completely cleared up! What kind of adverse side effects can you get if you stop abruptly?

Hope you & bubba are doing well ❤️ Xx

Purpledoggy profile image
Purpledoggy in reply to PaulaDag

Stopping steroids abruptly can cause an acute deficiency in your natural adrenal hormones, which causes severe drop in blood pressure, major electrolyte disturbances, and in some cases diarrhoea and gut bleeding. It’s not guaranteed to happen, especially on a short course, but it may lead to hospitalisation if it does. So, best avoided!!

Progesterone with backup of oestrogen stops the period (imbalance either way causes bleeding). The 2ww is a bugger for symptoms-easily said but try to relax as much as you can! Xx

PaulaDag profile image
PaulaDag in reply to Purpledoggy

Yes I’m starting to struggle with lack of symptoms would rather have some but it’s only day 5 I guess. It’s dragging :(

Crikey that sounds unpleasant! I’ll def wean off then if we don’t get a positive just to be on the safe side. Thanks xxx

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