Low AMH and risk of OHSS

[Italy300618]

Hi ladies, I'm currently in the middle of our 3rd icsi cycle. A little background...I have low amh for my age (11 at 33yrs), but our main issue is male factor. My first cycle I was on max dose of menopur and ended up in hospital with moderate ohss, 10 eggs, 1 fertilised, nothing to transfer. 2nd cycle no changes to my meds 10 eggs again, I was uncomfortable after egg collection, but all was well, transferred 2 embryos BFN, nothing to freeze. Now private and at a new clinic, first time doing long protocol, with 375 gonal f for 7 days then 300 gonal with 75 menopur. At 2nd scan I had 22 follicles, but they weren't large enough to trigger to bring egg collection forward so the clinic reduced my meds to 150 gonal and 75 menopur. I started to get quite bloated but have felt really good throughout stims. On my scan on friday, I had 36 follicles, but they had grown well and happy with the progress. My oestrogen levels were 15000, is that high? However the nurse gave me some cabergoline tablets to take each night for 8 days to settle my ovaries, i didnt do a stimulation injection friday and theyve halved my trigger to 5000 gonasi which i did last night.

I'm quite uncomfortable today, and i look pregnant, I'm really worried about ohss again even though I have had more monitoring at our new clinic and feel reassured. Both the clinic and us want a fresh transfer as we have never been able to freeze anything in previous cycles.

I've always found recovery after egg collection painful and I so so scared for egg collection tomorrow.

Apart from lots of water and protein anything else I can do to help? I'm pretty much sofa bound.

I just think it's strange with low amh to always be at the ohss end?

Xx

[Lots8788]

Hello lovely. My AMH was 11 at 28 or 29 i think. 1st round long protocol with menopur and got 15 eggs. doing another fresh later this year and they are doing short protocol with lower dose of menopur to reduce risk of OHSS. I dont have any answers im afraid but know what you mean -it does feel a bit odd the whole lower amh / ohss risk.

Also maybe try peppermint tea?

All the best for this round hun. x x x

[Italy300618 in reply to Lots8788]

Thanks for your reply and well wishes😘 and I wish you the best of luck with your next fresh cycle. I am hoping my clinic have done enough to reduce the risk, they do seem really on it 🤞🤞xx

[Lots8788 in reply to Italy300618]

Thanks hun. Yeah they do sound really on it and behind you which is great xxx

[Kbear83]

Good luck for your collection tomorrow. Must be worse when you know exactly what is to come. I have the grace of the unknown. Will be thinking of you, it really sounds like your new clinic are on top of things though.

All the best

Xxx

[Italy300618 in reply to Kbear83]

Ah thank you lovely! I will let you know ☺️ hope all is going well with your stims! Xx

[Hope04]

I was in a similar situation a few weeks ago. My first scan I had 6 follicles (they were on about increasing my menopur- it’s a good job they didn’t!) 2nd scan 13 follicles and my final scan over 30 follicles. So I triggered with half the dose and had cabergoline too.

I had 26 eggs collected in the end and my consultant scanned me 2 days after collection and there was fluid behind my liver so she said that unless I had nothing to freeze on day 5 then they would do a freeze all.

Luckily I ended up with 9 good embryos to freeze (didn’t have any to freeze my first round!) but I was so gutted I didn’t get my fresh transfer!

Keep drinking your water (3L per day), increase your protein and also try some lucozade sport (or anything with electrolytes in).

Keeping my fingers crossed for you xx