I am a 33 yr old female with a PhD in psychology. 1 year ago I had a dental cleaning and developed chest pain and palpitations shortly after. I had blood cultures and echos to rule out endocarditis. I also developed loose stool which prompted a GI workup (endoscopy and colonoscopy) which were negative. Right after the colonoscopy I developed low grade fever (no higher than 100 degrees) which still remains most days. I was able to somewhat function until a few months ago when I developed debilitating lightheadedness, fatigue, headaches, palpitations, tremors, shortness of breath, sensitivity to loud noise/light, and periods of disorientation/confusion. I often feel drunk and hungover for no reason. My symptoms became worse following a virus I had a few months ago. Heart monitors show PVCs and possible atrial ectopic heartbeats. The cardiologists and neurologists believe I have POTS syndrome. I have had blood tests for lyme and brain MRIs which were normal. My blood work is normal except for an elevated IGE level and an ANA that is slightly elevated (1:160). My vitamin levels are also all normal. I had a pelvic ultrasound which showed possible endometrial polys which I have to watch to make sure they are not anything else. I am not convinced I just have POTS syndrome because there is usually an underlying cause. Anyone have any thoughts?