Prostate Cancer Diet Update . . . August 2021

[cashlessclay]

Background: Biopsy, Oct 2006 (Gleason 4 + 3); Surgery, Jan, 2007 (Pathology, Gleason 3 + 3); PSADT @ 7 months. SRT, (Jan, 2011), PSA rising starting in March 2013.

A that point, I experimented with diet options. Using careful notes on my diet, and the Labcorp Ultrasensitive PSA test, I was able to come up with a working diet program, based on the hypothesis is that cancer cells need "insulin" and "iron" to grow. Receptors for each are overexpressed on cancer cells, when compared to normal cells.

This is what I'm doing:

1) Make sure supplements do not contain "sugar", "Iron" nor "Chondroitin Sulfate".

2) Minimize insulin and iron “spikes”.

3) Basic diet is (organic) vegan with some seafood. NO farmed raised fish, red meat, eggs, nor dairy.

4) For breakfast, I have steel cut oatmeal (not presoaked, cooked until dry, no milk), with walnuts and raspberries.

5) I start lunch and dinner with a plate of raw vegetables (especially broccoli and broccoli sprouts).

I have it with hummus made with olive oil, and add turmeric, black pepper, rosemary, oregano and parsley.

6) Use Olive oil when you need oil and brown over white for rice.

7) Have some soy (genistein), raspberries (ellagic acid), onions (quercetin), and capsaicin daily.

8) Green tea, with ginger, every morning and before dinner. Wait 30 min before having oatmeal.

9) Vitamin D-3 and METHYL B-12 are the only supplements I take, plus a brisk walk, about 30 minutes, every day.

The only reason I can talk about a PC diet is because 1), I tightly control what I eat, and 2), I get an ultra-sensitive PSA test from Labcorp about every 5-6 weeks. This allows me to do careful food experiments. Some food choices show up in PSA within days, others can take months, which makes drawing conclusions tricky. All tests have to be repeatable.

I chose to solve the insulin problem by limiting fast-carb intake; including some fats with the carbs; and keeping liquids to a minimum around carb intake.

I have not seen a PSA dependence on (wild caught) fish. I have as little as twice a month or as much as every day without seeing a change in diet performance. Shellfish can contain a lot of iron and I'm careful with oysters, clams and mussels.

I was concerned about taking a vitamin B12 supplement. Tried hard to get it from my diet, but was not successful. Seems that foods containing B12 were also high in "iron", and my PSA would go up. I have been taking Methyl B12 for over two years now, and have not seen any adverse affect on the diet. My blood levels of B12 are 5-600 pg/mL currently.

My PSA is "tracking" the diet. If I follow the diet strictly, PSA falls. If I ease up on the diet, PSA increases. If I break one of the diet rules, the PSA increases at a rate equal to my PSADT "prior" to the diet.

Results: PSA went from 0.067 in March 2013 to a peak of 0.525 in Nov. 2018, during the diet development phase. From Nov. 2018 till Dec. 2020, PSA has dropped to 0.187. At that point, I’m looking for a soft landing of PSA consistent with the Adaptive Therapy approach, developed at the Moffitt Cancer Center in Tampa, Florida. Here, keeping PSA low, but steady, is preferred over "undetectable". In that way, the remaining cancer serves as competition for resources needed by any new cancer mutation, that might be resistant to the treatment.

[2dee]

Thanks cashless for reporting on your non-scientific scientificially careful trial and error results. A lot of us don't have or won't take the time needed to "prove" and document our results.Too bad we can't multiply that by a factor of 1000.

I've been playing with diet for over 20 years, first for heart and then for PCa. Not sure I proved anything except I can be stubborn if I choose.

2Dee

[timotur]

CC: thanks for reporting, you have amazing results over eight years. I’m eating a diet similar to but not as a stringent as yours, and also believe keeping insulin under control is key. I monitor TG/HDL as a predictor of insulin resistance and keep it as close to 1:1 as possible, last test, TG:61/HDL:65. Once a week I do a 24hr fast, starting with a 4 mile run to keep glucose levels low. Would suggest adding a teaspoon of MCP on empty stomach. Keep up the good work.😀

[addicted2cycling]

Bravo!!! Your attention to *all of the details* is remarkable and I am in awe. 👍👍

I just can't find it within myself to live the rest of my life that way 'cause it's too much like work. Guess I'll simply skate my way around on the 5+5 thin ice surface until I fall through.

[dhccpa]

How is your whole fruit consumption? Peaches, apples, plums, grapes, bananas, etc.?

[cashlessclay in reply to dhccpa]

For the first seven years I limited fruits to apples (granny smith), raspberries and grapefruit. In the last year I included blueberries, strawberries, oranges and kiwi. So far it has worked, i.e. no harm done. I would be careful with higher GI fruit. Anything that taste "sweet" would be of concern to me. Smoothies that contained as little as 25-30% fruit have killed my diet. If taken 'after a meal' you might get better results.

[dhccpa in reply to cashlessclay]

I only eat whole fruit and only after a meal. I know some avoid it.

[Tony666]

What do you think of chia seeds?

[cashlessclay in reply to Tony666]

Tony, I never tried chia seeds. But the nuts and seeds that I have tried are in the "no harm done" bucket.

[louschu]

Since most pc is fat driven (choline scans work 10 times better than glucose). Curious how you monitor insulin and how important its seems to be. My diet was like your 12 years ago but now includes high protein meat like 99 percent fat free turkey and occasional lean grass fed beef

[cashlessclay in reply to louschu]

louschu, I do not measure insulin directly. But I have a pretty good idea what foods and preparations increase insulin response. Unexpected PSA results over the years have been mostly traced back to increased insulin or iron.

ncbi.nlm.nih.gov/pmc/articl...

ncbi.nlm.nih.gov/pmc/articl...

ncbi.nlm.nih.gov/pmc/articl...

[louschu in reply to cashlessclay]

I'm an athlete and going anemic is no fun. Took and iron supplement which turns out to be a free radical and saw an immediate spike. Now eat some beef and take vitamin C which helps proper absorption.

Saw a chia question. Have eaten it almost every day for years. Pretty sure its save and a good source of fat

[Jalbom49]

Most pc is fat driven? Ok. But according to DR Sarah Halberg, “You are not what you eat” YouTube video, a high saturated fat diet does not raise your serum or plasma saturated fat, and if anything, a high carb diet does via de novo lipogenesis.