Background: Biopsy, Oct 2006 (Gleason 4 + 3); Surgery, Jan, 2007 (Pathology, Gleason 3 + 3); PSADT @ 7 months. SRT, (Jan, 2011), PSA rising starting in March 2013.
A that point, I experimented with diet options. Using careful notes on my diet, and the Labcorp Ultrasensitive PSA test, I was able to come up with a working diet program, based on the hypothesis is that cancer cells need "insulin" and "iron" to grow. Receptors for each are overexpressed on cancer cells, when compared to normal cells.
This is what I'm doing:
1) Make sure supplements do not contain "sugar", "Iron" nor "Chondroitin Sulfate".
2) Minimize insulin and iron “spikes”.
3) Basic diet is (organic) vegan with some seafood. NO farmed raised fish, red meat, eggs, nor dairy.
4) For breakfast, I have steel cut oatmeal (not presoaked, cooked until dry, no milk), with walnuts and raspberries.
5) I start lunch and dinner with a plate of raw vegetables (especially broccoli and broccoli sprouts).
I have it with hummus made with olive oil, and add turmeric, black pepper, rosemary, oregano and parsley.
6) Use Olive oil when you need oil and brown over white for rice.
7) Have some soy (genistein), raspberries (ellagic acid), onions (quercetin), and capsaicin daily.
8) Green tea, with ginger, every morning and before dinner. Wait 30 min before having oatmeal.
9) Vitamin D-3 and METHYL B-12 are the only supplements I take, plus a brisk walk, about 30 minutes, every day.
The only reason I can talk about a PC diet is because 1), I tightly control what I eat, and 2), I get an ultra-sensitive PSA test from Labcorp about every 5-6 weeks. This allows me to do careful food experiments. Some food choices show up in PSA within days, others can take months, which makes drawing conclusions tricky. All tests have to be repeatable.
I chose to solve the insulin problem by limiting fast-carb intake; including some fats with the carbs; and keeping liquids to a minimum around carb intake.
I have not seen a PSA dependence on (wild caught) fish. I have as little as twice a month or as much as every day without seeing a change in diet performance. Shellfish can contain a lot of iron and I'm careful with oysters, clams and mussels.
I was concerned about taking a vitamin B12 supplement. Tried hard to get it from my diet, but was not successful. Seems that foods containing B12 were also high in "iron", and my PSA would go up. I have been taking Methyl B12 for over two years now, and have not seen any adverse affect on the diet. My blood levels of B12 are 5-600 pg/mL currently.
My PSA is "tracking" the diet. If I follow the diet strictly, PSA falls. If I ease up on the diet, PSA increases. If I break one of the diet rules, the PSA increases at a rate equal to my PSADT "prior" to the diet.
Results: PSA went from 0.067 in March 2013 to a peak of 0.525 in Nov. 2018, during the diet development phase. From Nov. 2018 till Dec. 2020, PSA has dropped to 0.187. At that point, I’m looking for a soft landing of PSA consistent with the Adaptive Therapy approach, developed at the Moffitt Cancer Center in Tampa, Florida. Here, keeping PSA low, but steady, is preferred over "undetectable". In that way, the remaining cancer serves as competition for resources needed by any new cancer mutation, that might be resistant to the treatment.
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