I am 63 years old. in Feb 2014, I was diagnosed with Prostate Cancer, Gleason Score 4+3 and preneural invasion. PSA was 4.18 . I had Radical Prostectomy in June 2014, . Pathological report showed all leanph nodes and seminal vesicles were intact. 50 days after surgery PSA detected 0.01 then it went up to 0.04, 0.14 and 0.24 and finally to 0.305 on Sep 20 2015, MRI showed a new tumor in prostate bed with dimension 10 *18 mm. an a suspected leanph node with 14 mm enlargement in mezzo rectum, both my Urologist and Oncologist recommended Radiation Therapy. My urologist believed that the leanph node is not involved, but my Oncologist told me that could not take risk and started aggressive radiation in 35 session with 3D Conformal Technic to pelvis on Dec 2015. 3 month after finishing treatment course, MRI and MRS was was taken from Pelvis and Abdomen distinguished that the tumor disappeared and the leanph nodes showed normal appearance and all organ were intact. but PSA rises to 1.03 in spite of successful Radiotherapy, with showed there is still something wrong. my Oncologist Started four month ADT in May 2016 with Eligard and then switched to 10.8 Zoladex in every 3 monthes the PSA dropped gradually to 0.036 in March 2017. after that the PSA trend reversed to.05, 0.067 and now is 0.77 so I went again for MRI that showed normal condition in Pelvis and abdomen. I had not any side effect with Radiation Therapy but my blood sugar increased to 212 and my blood pressure also increased after ADT, but now both are under control.
I had my normal life and activity in spite of little tiredness.but it seems that castration resistance is performed and my Oncologist now thinking about add Casodex to my treatment plan.
I appreciate to get advises from any of this community to fight with this brutal disease and win.