In November 2013 I was in a Northern California emergency room with severe lower back pain at age 65. Turned out I had previously undiagnosed, widespread metastatic prostate cancer. PSA was 5,006.4, with testosterone level of 908, and Alkaline Phosphatase around 424. Nuclear medicine bone scan lighted up like a Christmas tree. Extensive bone lesions and enlarged lymph nodes noted on CTs, from pelvis to neck. Biopsy of largest pelvic bed lymph node showed Gleason 4+4=8.
Fast-tracked straight to an oncologist and began systemic Androgen Deprivation Treatment with Lupron, supplemented with Zometa infusions for bones. PSA dropped to 2.4 within 3 months after testosterone fell to below 20. Pain went away. Alk Phos returned to around 50. PSA got as low as 1.0 and stayed below 2.0 for 15 more months. I have all the typical, but manageable, side effects of ADT, including hot flashes, libido changes, secondary sexual characteristics changes, some weight gain, etc. PSA then went up into the 4.0 range, and then was held down slightly as Casodex was added, then stopped, as no longer effective. In most recent months PSA rose from 5.9 to 11.2 to 18.1. Next step is likely to be Xtandi.
I attend several monthly local prostate cancer support groups, and find them quite helpful. My wife and I also participate in a weekly general, counseling-oriented, advanced cancer patients support group, and also find it quite helpful.