Can i take vacation when already 5 years PSA < 0.01

[Vasili]

Cancer of the prostate and pelvic lymph nodes found with PET 1, MRI, biopsy, PSA=100.

- After 6 cycles of chemotherapy with docetaxel and ADT-ELIGARD with PET 2 and PET 3 show a rapid decrease in the size of the lymph nodes and their emission of SUV, as well as the disappearance of several of them, a rapid decrease in the size of the prostate and SUV. After radiation SBRT only prostate PSA < 0.1, So I can't do PET4 to find out if there are nodules or if they are all gone. After 5 years of PSA < 0.01, T<5 ng/dl I hope from the long suppression of testosterone with ADT and because of its low production from my age, the testosterone will not rise quickly and I will have a long vacation without ADT. Of course, I will measure the testosterone more often, so that I can turn on ELIGARD again when necessary, so that the PSA does not increase.

[6357axbz]

good chance T will not recover after extended adt…mine didnt

[GoBucks]

Check out this clinical trial:

clinicaltrials.gov/study/NC...

I have been off meds 18 months after 4.5 years of ADT. My T has not recovered but I feel 100% better.

[Todd1963]

I think it’s fairly safe to say that there is no reason why you can’t take a hormone vacation. I took one at year four and I took another one around here 15. They only lasted about a year before PSA started creeping up and my doctor and I felt wish I should go back on treatment but it was fun while it lasted

[Tall_Allen]

There is no guarantee that the vacation is safe, and no guarantee that your T will recover (in which case it is safe, but pointless).

[Vasili in reply to Tall_Allen]

ако ваканцията е безопастна, може ли липсата на страничните ефекти от елигарда, да оправдаят ваканцията?

[Todd1963 in reply to Tall_Allen]

I found my T recovered quickly but my Adrenal system never recovered

[Radars in reply to Tall_Allen]

I finished rt/ht 2016 my t has not recovered, I have asked for trt but no,and now I have severe osteoporosis, I am going for a spinal x-ray for back pain because I must have fractured because of back pain.

[VCinTx in reply to Radars]

Two years after my IMRT I fell and I had back pain. X-ray didn't show a problem and I was prescribed rehab for my back. After two more months my pain continued and after going to a regular visit with my RO, he requested an MRI. This showed a compression fracture of L5 and a crack in L3. I was given a Kyphoplasty procedure and it was a miracle. Pain has stopped and I am regaining my walking and exercising again. Good luck to you!

[Radars in reply to VCinTx]

we're you a bit breathless with your compression fracture, I was speaking to a ros nurse and she said I have probably got compressed disc's reducing lung capacity. do you have severe osteoporosis.

[Kayakbob]

after 3 yrs adt with PSA unmeasurable, started ADT vacation. Oncologist said it would only last 6-9 months till PSA rise, agreed to go back on ADT when PSA hit 10 - vacation lasted over 6 years before PSA jumped - it was a GREAT period! Now, after surgery to vertebra, radiation , and Pluvicto, and ADT with Enzalutamide added for over a year, PSA unmeasurable, I'm on vacation again as of Jan 1st! What a ride!!

[VCinTx]

I have osteopenia and I am scheduled for a DEXA scan to check bone density. Be sure to get a MRI for the correct diagnosis.

[RMontana]

See if this helps...sent the same message to another post that was similar to yours...

Take a look at this article; you may want to consider intermittent ADT going forward...if my PSA comes back I will not go back on full time ADT again but will do IADT. There are some counterindications in this podcast regarding TET therapy and its impacts, especially in the 1st year of ADT treatment. Its important to see the results of the one study posted but the implications from this presentation are clear; higher TET is not protective during the 1st year of ADT…afterwards it appears that intermittent treatment with its introduction of TET, does not appear to affect OS and can improve QOL. See this part of the podcast;

MIN 16:40 – Goal for low TET level during initial 1st year of ADT treatment. Study of 626 patients. Patients w fully suppressed TET below 20 ng/dL in 1st year were 2 times (HR =1.90) less likely to develop CRPC (castrate resistant PCa) than those with TET higher than 50 ng/dL. P=0.015; 1.5% chance results are wrong. They also had 10 year Median time to progression! Conclusion; initial high TET is not protective over CRPC outcomes. Rick

healthunlocked.com/active-s...