can you you help me with this case.
patient is 27 yrs old who developed acute renal failure requirind dialysis.
Renal biopsy was done and showed double glomerulopathy with pauci-immune GN and membranous nephropathy.
She was advised for IV cyclophosphamide but refused due to fertility issues.
So, Rituximab was started 375mg/m2 weekly for 4 doses in addition to prednisolone 1 mg/kg/day.
what is next?
How to decide whether maintenance therapy should be given or not?
how long after the last Rituximab dose shall we wait to decide on therapy failure or the need for maintenance therapy?
Thanks for cooperation.