further advice on blood results : I posted for... - Thyroid UK

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further advice on blood results

Poppygriff691 profile image
9 Replies

I posted for advice about a month ago and increased my T3 to 10mcg . I have felt some improvement as in not as achy but not sleeping very well. I am in Australia visiting my daughter so took advantage of their cheaper blood testing

I started T3 as my doctor thought I wasn’t converting T4 but having researched it more it could be that I just needed a dose increase of T4 ? I have only ever taken 50mcg which I am still on now with the T3 10mcg.

TSH 0.88 (0.5- 4)

FT4 11( 10-20)

FT3 4.4 (3.5-6.5)

Reverse T3 317(170-539)

Ratio of T3 to RT3 13 (>20)

Zinc 16.4 (10-18)

Selenium 1.73( 0.80-1.99)

I realise ideally bloods should be done at the same lab. I followed the usual protocol described on here regarding medication prior to testing . The ratio of T3 to reverse T3 is lower than it should be. Does this indicate a conversion problem ?

My question is do you think I should ask my doctor to increase my Levo from 50mcg or increase my T3 from 10 .

Would really like some advice. Thanks

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9 Replies
FallingInReverse profile image
FallingInReverse

I was in exactly the same position. 50 Levo then added 10 Lio.

Right after that I found this board and realized I probably didn’t need any Lio at all.

I have taken the last few months to get my T4 dose up. Keeping my T3 at 10 for now.

So that is what I chose to do !

Poppygriff691 profile image
Poppygriff691 in reply toFallingInReverse

Thanks for your reply that’s really interesting . Do you feel better with this ? I realise it takes longer for improvement with T4 but definitely less complicated and cheaper if it works for you !

FallingInReverse profile image
FallingInReverse in reply toPoppygriff691

I'm not sure if it technically takes longer to improve on T4. I see getting my T4 to optimal as the very first pillar in my dosing.

50 Levo (even with the 10 Lio) wasn't bringing me to the mid/top of range at all (of either, but def not T4). There are discussions here about whether those on Lio with optimal FT3 need to worry about a low T4. I am not 100% read up on it, but my conclusion is that not everybody needs an optimal T4 when T3 is OK, but for me, while I adjust everything, I would like to know that my body has a reserve of stable and optimal T4 to draw on regularly.

The big thing for me is that as long as I convert well, and until I give myself a chance to, there was no reason to start the Lio.

I wish I had followed this plan - said succintly below, But here I am.

healthunlocked.com/thyroidu...

Poppygriff691 profile image
Poppygriff691 in reply toFallingInReverse

Yes I think you’re right . It would have been better if my doctor had increased my Levo originally. I will probably do what you have done and see how I go . Thanks so much for sharing your experience with me . Hope we all feel amazing soon !

SlowDragon profile image
SlowDragonAdministrator

Definitely get levothyroxine dose increased up to 75mcg daily

Retest again in another 8 weeks

Which brand of levothyroxine is 50mcg

Poppygriff691 profile image
Poppygriff691 in reply toSlowDragon

Thanks . I am taking Accord levothyroxine.

Sorry I can’t find my blood results for November at the minute but will look when I get home.

I am gluten and dairy free and have positive antibodies . Just tested positive to the MTHFR C677T Mutation: DETECTED HETEROZYGOUS.

I do take methylated folate daily already so hope this helps.

I was negative for celiac when tested a year ago.

SlowDragon profile image
SlowDragonAdministrator

previous post

healthunlocked.com/thyroidu...

Blood results on levo and no T3 in November 23

TSH 1.66

FreeT4 14,6

FreeT3 2.80

On 50mcg

Please add ranges on Ft4 and Ft3

Your results showed you were in need of dose increase in levothyroxine

Hardly surprising as 50mcg is only standard STARTER dose

SlowDragon profile image
SlowDragonAdministrator

Are you on gluten free diet or dairy free diet

About 90% of primary hypothyroidism is autoimmune thyroid disease, usually diagnosed by high TPO and/or high TG thyroid antibodies

Autoimmune thyroid disease with goitre is Hashimoto’s

Autoimmune thyroid disease without goitre is Ord’s thyroiditis.

Both are autoimmune and generally called Hashimoto’s.

In U.K. medics hardly ever refer to autoimmune thyroid disease as Hashimoto’s (or Ord’s thyroiditis)

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances.

Most common by far is gluten.

Dairy is second most common.

A trial of strictly gluten free diet is always worth doing

Only 5% of Hashimoto’s patients test positive for coeliac but a further 81% of Hashimoto’s patients who try gluten free diet find noticeable or significant improvement or find it’s essential

A strictly gluten free diet helps or is essential due to gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and may slowly lower TPO antibodies

When you get home……While still eating high gluten diet ask GP for coeliac blood test first as per NICE Guidelines

nice.org.uk/guidance/ng20/c...

Or buy a test online, about £20

Assuming test is negative you can immediately go on strictly gluten free diet 

(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially) 

Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

drknews.com/changing-your-d...

Non Coeliac Gluten sensitivity (NCGS) and autoimmune disease

pubmed.ncbi.nlm.nih.gov/296...

The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported

nuclmed.gr/wp/wp-content/up...

In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned

restartmed.com/hashimotos-g...

Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.

Similarly few months later consider trying dairy free too. Approx 50-60% find dairy free beneficial

With loads of vegan dairy alternatives these days it’s not as difficult as in the past

Post discussing gluten

healthunlocked.com/thyroidu...

SlowDragon profile image
SlowDragonAdministrator

Guidelines when ONLY on levothyroxine is that most people will need to slowly increase levothyroxine, usually in 25mcg steps, until on approximately 1.6mcg per kilo of your weight per day

Unless extremely petite that will be at least 100mcg levothyroxine per day

Some people need a bit less…..some a bit more

Once on approx this dose …..Ft4 towards top of range, vitamin levels optimal…..if Ft3 remains low

When T3 is added ….. dose levo may be reduce by 25mcg.

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