TSH extremely low but low-ish free T3 and free T4 - Thyroid UK

Thyroid UK

141,182 members166,423 posts

TSH extremely low but low-ish free T3 and free T4

Suzanne-j profile image
31 Replies

Hi, I'm here again. 3 doctors in and six years down the line. I can't seem to get any help.

My results are totally confusing me. I researched and have come up with an idea but would like some feedback.

I was on 2.5 grains of armour but have been switched to Novothyral 100, 8 weeks ago

I have hashimoto 6 years, I'm dairy free gluten free and follow a strict diet. I have a form of blood cancer so am unable to take b12 and iron. However my vit d is very good and I follow the suggested supplements required. Selenium magnesium etc etc, as advise by Dr wentz thyroid pharmacist.

Weight gain it's getting out of control alongside severe constipation!

My latest lab results due to my sweating (soaking) and being jittery! (Anxious and fast) and horrendous constipation.

TSH L 0.01 Range 0.27 - 4.20 mU/L

T4 Total 79.0 Range 66-181 nmol/L

Free T4 14.5 Range 12.0 - 22.0. pmol/L

Free T3 4.81 Range 3.1 - 6.8 pmol/L

I'm desperate to go to the toilet. My diet is good I eat veg and fruit, I'm a seasoned researcher and follow Dr Isabella Wentz. I just need to know why my TSH is so low but my free T3 and free T4 are not where they should be, they are on the low side too and I still feel hypo apart from sweating and anxiety.

I really need help. Please.

Written by
Suzanne-j profile image
Suzanne-j
To view profiles and participate in discussions please or .
Read more about...
31 Replies
Lalatoot profile image
Lalatoot

Tsh is often low and suppresses when we take t3. My TSH is undetectable.When you take NDT you judge your dose by how you feel and your ft4 and ft3 levels.

Sweating and anxiety are also hypothyroid symptoms.

Suzanne-j profile image
Suzanne-j in reply toLalatoot

Thank you for your reply. I should up my dose again then and probably go back to Armour. It's all a bit confusing when the symptoms can be both hypo and hyper.

Lalatoot profile image
Lalatoot in reply toSuzanne-j

It is confusing that is why we need to take ft4 and ft3 levels into account as well as how we are feeling. I was hyperthyroid, had my thyroid taken away and am now hypo. I can say from experience that I have had the same symptoms hypo as I did hyper.

Suzanne-j profile image
Suzanne-j in reply toLalatoot

Thank you this is so helpful. I appreciate you sharing your thoughts it makes me feel less like I'm going mad.

joey82 profile image
joey82

Your FT3 & FT4 are probably low because your are a poor converter. It's possible to have anxiety with hypothyroidism. Your HP (hypothalamus pituitary) connection won't be getting the adequate T3 it needs to stimulate cortisol release by the adrenals. The adrenals compensate for this by dumping adrenaline into thr body.

Suzanne-j profile image
Suzanne-j in reply tojoey82

Thanks for your reply. Do you think this could be why I'm gaining weight so rapidly? My belly fat is so disproportionate to the rest of my body!

SlowDragon profile image
SlowDragonAdministrator

Novothyral is just levothyroxine on it’s own….no T3

Why were you changing from Armour to levothyroxine

Essential to test vitamin D, folate, B12 and ferritin

Suzanne-j profile image
Suzanne-j in reply toSlowDragon

Novothyral is both t4 and t3 in the ration if 100/15

My Dr changed as it's one tablet and said she was on it and said it would suit me as I'm constantly constipated.

As I mentioned I have a blood condition and am not able to take b12 folate ferritin etc. I am discussing this at my next onco appointment. However vit d is reasonable am am supplementing.

Thank you.

pennyannie profile image
pennyannie in reply toSuzanne-j

Even with a split T3/T4 medication you may well find you need to try supplements in order to achieve a regular bowel movement.

I take vitamin C to bowel tolerance.

Are you in the UK as Novothyral is not routinely prescribed on the NHS ?

Suzanne-j profile image
Suzanne-j in reply topennyannie

Oh that's very useful thank you. Would you be kind enough to tell me what dose and brand please. This is the bane of my life and really gets me down. I take vit D as I've read being low on that can cause it too.

pennyannie profile image
pennyannie in reply toSuzanne-j

No thyroid hormone replacement works well until your core strength vitamins and minerals - those of ferritin, folate, B12 and vitamin D - are up and maintained at optimal levels .

Do you have any recent results of these ?

We are all different - I'm without a thyroid for starters - and my optimal dose of vitamin C - probably will not be yours - as it' trial error along with what you eat and how fast your metabolism is running.

There are a multitude of products - I just think vitamin C can't hurt me and the excess is excredited out with any luck !

Suzanne-j profile image
Suzanne-j in reply topennyannie

No recent results for the said vitamins but from past results I know they are not great but also not rock bottom. I make too many red blood cells so I'm not able to supplement with all these vitamins. The doctors have to keep my bone marrow steady otherwise I have to have too many venesections. I'm also trying to put off taking hydroxycarbamide. This is why I reach out on this forum to try and get support for my symptoms etc.

pennyannie profile image
pennyannie in reply toSuzanne-j

Is this being prescribed in the UK by the NHS ?

Suzanne-j profile image
Suzanne-j in reply topennyannie

No a private Doctor. NHS wouldn't even consider any form of t3 for me and I was ill for a long time until I joined here and put myself on Armour before I found a Dr on the thyroid uk list. However he recently passed away so I've had to find another.

SlowDragon profile image
SlowDragonAdministrator in reply toSuzanne-j

Sorry

Ok yes you’re correct

But obviously your results suggest you’re not on high enough dose

FT4: 14.5 pmol/l (Range 12 - 22)

Ft4 is only 25.00% through range

FT3: 4.81 pmol/l (Range 3.1 - 6.8)

Ft3 better at 46.22% through range

Request 25mcg dose increase in Novothyral

(Think the smallest tablet is 50mcg ….so cut in half to get 25mcg)

Suzanne-j profile image
Suzanne-j in reply toSlowDragon

Sorry that should say 100/20

pennyannie profile image
pennyannie

What is printed on the Novothyral outer box - is it a spilt dose - such as 100/20 : 75/15 ;

or just one dose with no split - such as 100 :

Suzanne-j profile image
Suzanne-j in reply topennyannie

It is printed as 100/20 t4 and t3 respectively.

pennyannie profile image
pennyannie in reply toSuzanne-j

OK so you are taking a tablet containing 100 T4 + 20 mcg T3 :

So this breakdown of T3 and T4 is at a 1/ 5 ratio T3 to T4 :

I think Novothyral is a German brand which is not licensed in the UK and made by Merck and think they make one tablet at a 1/4 ratio T3/ T4 which may suit you better if you do not find relief of symptoms on the dose ratio.

Suzanne-j profile image
Suzanne-j in reply topennyannie

Oh Wow that's so helpful thank you so much I will ask my Dr to prescribe this for me. Could I please ask if you know the t4 t3 of the 1/4 ratio so I can go to her better equipped. Thank you.

pennyannie profile image
pennyannie in reply toSuzanne-j

Where are you living and getting your prescription filled ?

Why were you taken off Armour ?

1 grain Armour holds 9mcg T3 + 38 mcg T4 - so at around a 1/4 ratio -

were your bowels easier on Armour - if so likely a 1/4 ratio T3/T4 suits you better :

pennyannie profile image
pennyannie in reply toSuzanne-j

Having just done quick look - it seems all the Novothyral split doss are at a 1/5 ratio :

Sorry about that - I'm sure there was a 1/4 - T3/T4 ratio when i last looked a few years ago - but seems not;

Suzanne-j profile image
Suzanne-j in reply topennyannie

I get my script filled in the UK. I was taken off Armour because a while back my free t3 was good but my t4 and free t4 were always at the very lower end of the range. Plus my Dr said that it might help with the bathroom.

pennyannie profile image
pennyannie in reply toSuzanne-j

On NDT - brands of Armour/ Efra - or whatever - it is all about tracking on the T3 :

Once optimally medicated you will have a T3 proportionally much higher in the range than the T4 - it does not matter - and a TSH - low suppressed - as this is how Natural Desiccated Thyroid ' looks ' in blood test results.

NDT does not present the same way of synthetic T3 and T4 medications.

I take NDT but still have lingering hypo symptoms - and why I take vitamin C to bowel tolerance to resole some issues.

Suzanne-j profile image
Suzanne-j in reply topennyannie

Ok this has been incredibly helpful. It's also made me decide to return to Armour and titrate. For me it's a confidence thing and after losing Dr Callebout I felt so alone. Thanks again

pennyannie profile image
pennyannie in reply toSuzanne-j

No worries -

you are not alone with all this - we are here - and keep us in the loop :

SlowDragon profile image
SlowDragonAdministrator in reply toSuzanne-j

I was taken off Armour because a while back my free t3 was good but my t4 and free t4 were always at the very lower end of the range. Plus my Dr said that it might help with the bathroom.

On NDT Ft4 is almost always low

Some people find they need to add some levothyroxine alongside Armour

SlowDragon profile image
SlowDragonAdministrator

Please add country you live in to your profile…..

don’t think you are in U.K.?

Suzanne-j profile image
Suzanne-j in reply toSlowDragon

I'm in the UK. I'll add now sorry!

Suzanne-j profile image
Suzanne-j in reply toSuzanne-j

No it says UK already! I do t k is why it doesn't show.

SlowDragon profile image
SlowDragonAdministrator in reply toSuzanne-j

Try deleting country then save

Then add country back in and save

Not what you're looking for?

You may also like...

Optimizing Free T3 to resolve symptoms?

Hi All Im currently taking 25mcg of Levothyroxine as prescribed by my GP. My results are as...
Hypokid profile image

New blood results T3, T4, TSH

Hi everyone ❤️ I had my blood work for thyroid on 29th March, I was shocked to see the results as...
birkie profile image

Graves and low end T3 and jitters

Hello I am on 1.25 mg Methimozole Graves’ disease My recent results are TSh 1.62 (.32-4) mlu/l)...
cgauthie profile image

Low Free T3

Hi, I've been looking for a posting with results similar to mine. Does anyone have an idea why my...
SimonA87 profile image

SLIGHTLY HIGH FREE T3 BUT MANY HYPERTHYROID SYMPTOMS

Hi I'm looking for advice please. Because I was feeling very tired and weak etc I had a private...
Aspiegirl profile image

Moderation team

See all
Jaydee1507 profile image
Jaydee1507Administrator
PurpleNails profile image
PurpleNailsAdministrator
SlowDragon profile image
SlowDragonAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.