Levels update: Hi, so I’ve posted a couple of... - Thyroid UK

Thyroid UK

141,182 members166,423 posts

Levels update

EllsBells591 profile image
22 Replies

Hi, so I’ve posted a couple of questions but didn’t have an up to date set of results. I received them back today.

TSH 0.41mIU/L. Range 0.27 - 4.2

Free T3 4.7pmol/L. Range 3.1 - 6

Free Thyroxine 17.9pmol/L Range 12 - 22 

THYROGLOBULIN ANTIBODIES 48.3kIU/L Range 0 - 115 

THYROID PEROXIDASE ANTIBODIES  225.7kIU/L Range 0 - 34

FOLATE - SERUM 25.4nmol/L Range 8.83 - 60.8

VITAMIN B12 - ACTIVE  48pmol/L Range 37.5 - 188

VITAMIN D  150nmol/L Range 50 - 250

FERRITIN  88ug/L Range 30 - 150

I’m disappointed in my ferratin and B12 and am being a lot more strict with my supplements now. Also gutted about my antibodies as they had been falling steadily but have risen by almost 100 since my last test.

I’m never too sure about T3 levels? Any advice or insights as to any areas I should concentrate on would be appreciated. TIA.

Written by
EllsBells591 profile image
EllsBells591
To view profiles and participate in discussions please or .
Read more about...
22 Replies
SeasideSusie profile image
SeasideSusieRemembering

EllsBells591

Did you do the test as we advise:

* No later than9am

* Nothing to eat or drink except water before the test

* Last dose of Levo 24 hours before the test

* No biotin or any supplement containing biotin (eg B Complex) for 3-7 days before the test

If so then if you feel symptomatic there is room for an increase in your Levo as your FT4 is 59% through range and FT3 is 43.24% through range if the range is actually 3.1-6.8, but if it is actually 3.1-6 then it's 55.17% through range.

Antibodies are going to fluctuate, that's the nature of Hashi's, so not much you can do about that really.

FOLATE - SERUM 25.4nmol/L Range 8.83 - 60.8

Folate is recommended to be at least half way through range so that would be about 35 plus with that range, you might want to improve this level.

VITAMIN B12 - ACTIVE 48pmol/L Range 37.5 - 188

This is very low. Active B12 below 70 suggests testing for B12 deficiency according to Viapath at St Thomas' Hospital:

viapath.co.uk/our-tests/act...

Reference range:>70. *Between 25-70 referred for MMA

There is a link at the bottom of the page to print off the pdf to show your GP when asking for testing for B12 deficiency and Pernicious Anaemia.

Do you have any signs of B12 deficiency – check here:

b12deficiency.info/signs-an...

b12d.org/submit/document?id=46

If you do then list them to discuss with your GP and ask for testing for B12 deficiency and Pernicious Anaemia. Do not take any B12 supplements or folic acid/folate/B Complex supplements before further testing of B12 as this will mask signs of B12 deficiency and skew results and if you have B12 deficiency and it is not detected and treated then this could affect your nervous system. B12 deficiency should be treated before starting folic acid because folic acid can sometimes improve your symptoms so much that is masks B12 deficiency.

VITAMIN D 150nmol/L Range 50 - 250

This is a good level and in accordance with the recommendation of the Vit D Council, Vit D Socieity and Grassroots Health who all recommend a level of 100-150nmol/L.

Do you have a ferritin and CRP result?

EllsBells591 profile image
EllsBells591 in reply toSeasideSusie

I did follow the recommendations, yes 🙂

FERRITIN  88ug/L Range 30 - 150

CRP 0.21mg/L

B12 I’m vegan and had gone a while without supplementing.

SeasideSusie profile image
SeasideSusieRemembering in reply toEllsBells591

What was your B12 level when supplementing?Ferritin is OK.

EllsBells591 profile image
EllsBells591 in reply toSeasideSusie

I’ve been out today and actually still away from home so can’t check the previous B12 right now. Thank you so much for the really comprehensive reply and links. Fascinating re the B complex results - I do have some of those symptoms, but put them down to hypothyroidism.

* Tinnitus

* Restless legs (on and off)

* balance issues, nothing awful - I don’t fall but do walk into things/over balance

* I’ve always had a weird thing with pain, I went to the dentist ages ago and told them I had a pain on the right side of my jaw, but they found an abscess on the left side

* palpitations

* Constipation

* Tired

* forgetting words/names

I see medichecks does the test you mention. I doubt my Doctor would approve it 🫤

Whereabouts do I need the FT3 and 4 to be? 75%?

Thanks again so much.

Ellie

SeasideSusie profile image
SeasideSusieRemembering in reply toEllsBells591

Whereabouts do I need the FT3 and 4 to be? 75%?

Hard to say, we are all different, there are no hard and fast rules. Generally someone on Levo only would feel best when FT4 and FT3 are in the upper part of their ranges, but nobody can say where you will feel best because your optimal levels will likely be different from someone else's optimal levels.

SlowDragon profile image
SlowDragonAdministrator

Low B12 symptoms 

b12deficiency.info/signs-an...

methyl-life.com/blogs/defic...

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a separate B12 supplement and add a separate vitamin B Complex after a week 

Then once your serum B12 is over 500 (or Active B12 level has reached 70), you may be able to reduce then stop the B12 and just carry on with the B Complex.

If Vegetarian or vegan likely to need ongoing separate B12 few times a week 

B12 drops 

natureprovides.com/products...

Or

B12 sublingual lozenges 

uk.iherb.com/pr/jarrow-form...

cytoplan.co.uk/shop-by-prod...

B12 range in U.K. is too wide

Interesting that in this research B12 below 400 is considered inadequate 

healthunlocked.com/thyroidu...

B complex

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid) 

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid 

healthline.com/nutrition/fo...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule) 

Thorne currently difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay 

Other options 

healthunlocked.com/thyroidu....

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate methyl folate supplement and continue separate B12

How other member saw how effective improving low B vitamins has been 

healthunlocked.com/thyroidu...

EllsBells591 profile image
EllsBells591 in reply toSlowDragon

Thank you so much for all the information. Will order some of the Thorne complex 👍🏻

SlowDragon profile image
SlowDragonAdministrator

No TPO antibodies result?

Ft3…..is range 3.1 - 6.8

EllsBells591 profile image
EllsBells591 in reply toSlowDragon

Sorry missed that one but have added it now :

THYROID PEROXIDASE ANTIBODIES  225.7kIU/L Range 0 - 34

SlowDragon profile image
SlowDragonAdministrator in reply toEllsBells591

So confirms Hashimoto’s

Can see on your profile you’re already on gluten free diet

EllsBells591 profile image
EllsBells591 in reply toSlowDragon

Yes, my other antibodies used to be high but went back to in range when I changed to gluten free.

EllsBells591 profile image
EllsBells591 in reply toSlowDragon

Are my T3 and T4 optimal?

SlowDragon profile image
SlowDragonAdministrator in reply toEllsBells591

was this private test

Usually Ft3 range is 3.1 - 6.8

EllsBells591 profile image
EllsBells591 in reply toSlowDragon

medichecks

EllsBells591 profile image
EllsBells591 in reply toSlowDragon

FT3 Range

FT3 range
Jaydee1507 profile image
Jaydee1507Administrator in reply toEllsBells591

Free T4 (fT4) 17.9 pmol/L (12 - 22) 59.0%

Free T3 (fT3) 4.7 pmol/L (3.1 - 6.8) 43.2%

These are not optimal results. I would expect FT4 to be in the top quarter of the range. Your TSH is at .41 though and you will struggle to get GP to raise your dose.

Low B12 often results in a low TSH, so work hard on your B12 and see if you can get GP to retest in a few months time.

EllsBells591 profile image
EllsBells591 in reply toJaydee1507

Thank you. I’ve ordered some Thorne B complex so will give that a go.

Jaydee1507 profile image
Jaydee1507Administrator in reply toEllsBells591

See advice in this response from SlowDragon, as your B12 is so low you need 2 types of B12 initially. healthunlocked.com/thyroidu...

EllsBells591 profile image
EllsBells591 in reply toJaydee1507

Thank you, I’ve got B12 and have been re-taking it since I did the test.

Bearo profile image
Bearo in reply toJaydee1507

I don’t think I’ve read that, before, that low B12 can lower TSH. Is there a reference for that or an explanation? Might be useful ammo for the GP at some future date.

Jaydee1507 profile image
Jaydee1507Administrator in reply toBearo

I'm not sure that I can find an official enough paper that your GP might take notice of. Not sure if SeasideSusie can help.

Low B12 lowers conversion of T4 to T3 so that may well be the explanation.

melissaforeman.co.uk/the-im...

Bearo profile image
Bearo in reply toJaydee1507

thanks, Jaydee

Not what you're looking for?

You may also like...

Update to my test results

I have now received my 2nd lot of test results concerning my Thyroid etc. They are as follows:-...
Hustler profile image

Blood Results - Are They Normal?

Hi I wonder if anyone can help with the interpretation of my blood results. I have been having...
engo profile image

My Thyroid test results

21 Sep 2021 TSH 21.3 mIU/L Range: 0.27 - 4.2 R Free T3 2.6 pmol/L Range: 3.1 - 6.8 Free...

Blood test results help - Low T3 and T4

Hi everyone! I made a post the other day about my symptoms, deficiencies/bottom of range B12,...
liaratsoni profile image

Haemachromatosis?

I am going to see my GP on Thursday morning re my recent Medichecks results and have had lots of...
Parody103mg profile image

Moderation team

See all
Jaydee1507 profile image
Jaydee1507Administrator
PurpleNails profile image
PurpleNailsAdministrator
SlowDragon profile image
SlowDragonAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.