I have now had a full Thyroid blood test in London. The results are as follows:
T4. 96 (59 - 154)
TSH. 1.01 (0.27 - 4.2)
Free Thyroxine. 18.1 (12.0 - 22.0)
Free T3 4.0. (3.1 - 6.8)
Thyroglobulin Antibody. 172. (0 - 115)
Thyroid Peroxidase Antibodies. 173. (0 - 34)
Vitamin D. 58. (50 - 200)
Vitamin B12. 446. (197 - 771)
Folate (serum). 6.7. (> 2.9)
Ferritin. 104. (13- 150)
C Reactive protein. 3.1 (< 5.0)
I would be very grateful for any comments. Why are the antibody results so far out of kilter and what can I do about them?
I am currently on 112.5 mcg Levothyroxine plus Vitamin D supplement but still have lots of symptoms including indigestion, brain fog, over active bowel, fatigue and generally feel unwell, particularly between breakfast and lunch.
I think I am extremely sensitive to thyroxine. Would I be better off trying Armour? If so, where is best to source it? Look forward to hearing any suggestions/advice of the best way forward...
Many thanks
LizT10
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LizT10
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In what way do you think you are sensitive to Levo?
How did you take this test? What time of day? When was last dose of Levo before test? Recommend 24hrs last dose and fast day of test taking it at 9am.
Your antibodies are raised as you have autoimmune thyroid disease called Hashimoto's. It's possible to have results in the thousands. people with Hashi's often benefit from a gluten free diet, some others need to eliminate dairy. Have you tried this?
Free T4 (fT4) 18.1 pmol/L (12 - 22) 61.0%
Free T3 (fT3) 4 pmol/L (3.1 - 6.8) 24.3%
Your conversion isn't great but you have plenty of room for a 25mcg dose increase. Getting vitamins OPTIMAL will also help conversion and how you feel.
Folate is quite low. Try a good B complex that has active or methyl vitamins. This will keep your B's in balance and also help you B12. This one is good. amazon.co.uk/Yipmai-Liposom...
Ferritin is good but continue to eat red meats etc
Thank you very much for your comments. I had the test at 9.30 am which was 12 hours after my last thyroxine dose. Next time I will make sure it is 24 hrs.
I think I will up my vitamin supplements and increase my thyroxine to 125 mcg and hope that improves things.
Yes, I cut a 25 mcg pill in half to get to 112.50. I have been on that dose since November. I felt fine for about 8 weeks but since then all the usual symptoms have returned. I will increase to 125 mcg and add some more supplements and hope that helps.
I have had a coeliac test which came back negative so if the increase in thyroxine doesn’t help, I will go gluten free and see if that does the trick.
Get GP to increase number of 50mcg Accord tablets and cut in half to get 25mcg
Use pill cutter or sharp craft scalpel
Get weekly pill dispenser to keep spare half in for next day
Teva brand upsets many, many people
Northstar levothyroxine being phased out this month
Many patients do NOT get on well with Teva brand of Levothyroxine. Teva is lactose free.
Teva contains mannitol as a filler instead of lactose, which seems to be possible cause of problems. Mannitol seems to upset many people, it changes gut biome
Teva is the only brand that makes 75mcg tablet.
So if avoiding Teva for 75mcg dose ask for 25mcg to add to 50mcg or just extra 50mcg tablets to cut in half
But for some people (usually if lactose intolerant, Teva is by far the best option)
Aristo (currently 100mcg only) is lactose free and mannitol free.
Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels
Low vitamin levels affect Thyroid hormone working
Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances.
Most common by far is gluten.
Dairy is second most common.
A trial of strictly gluten free diet is always worth doing
Only 5% of Hashimoto’s patients test positive for coeliac but a further 81% of Hashimoto’s patients who try gluten free diet find noticeable or significant improvement or find it’s essential
A strictly gluten free diet helps or is essential due to gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)
Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and may slowly lower TPO antibodies
While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first
Assuming test is negative you can immediately go on strictly gluten free diet
(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)
Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse
The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported
In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned
Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.
Similarly few months later consider trying dairy free too. Approx 50-60% Hashimoto’s patients find dairy free beneficial
Thank you so much for your comments. I am going to increase my thyroxine dose to 125 mcg and add more vitamin supplements. If that doesn’t improve matters I will go gluten free. My previous coeliac test came back negative.
muesli with little milk and banana followed by a slice of toast with butter and marmalade. I eat a lot but have lost weight recently and am not overweight - BMI is 23 or so.
It's just you said you feel worse after breakfast so perhaps there's an issue with what you are eating? Thats quite a high carb content breakfast with gluten and dairy. Many Hashi people find gluten and issue, next is dairy.
You could try swapping it out for an egg based breakfast and see if that helps.
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