Trying to conceive baby no 2 did a full thyroid and vitamins on Thriva please help!!!!

[Krin]

TPO is high 131.5 klu/l ,What does that mean?

Free thyroxine (FT4) is slightly high 22.3pmol

Triiodothyronine (FT3) 4.9pmol/L Optimal

Thyroxine (T4) 157nmol/L Normal

Thyroglobulin antibodies (TgAB) 40.4 kU/L Normal

Thyroid peroxidase antibodies (TPOAb) 131.5

kIU/L High

Thyroid-stimulating hormone (TSH) 1.33 mIU/L Optimal

Active B12 141pmol/L Normal

Ferritin 48 ug/L Optimal

Vitamin D 98 nmol/L Optimal

Please help me understand what high TPO is? And slighting high T4. When I had T4 and TSH tested with GP last month T4 was 17 and TSH was 2.6 now 1.33

For over a month I’ve been on 75mcg levothyroxine and trying to conceive baby no 2

Please help thanks

[SeasideSusie Remembering]

Krin

Please help me understand what high TPO is?

It means that the cause of your hypothyroidism is autoimmune, the most common reason for hypothyroidism. This is where the immune system attacks the thyroid and gradually destroys it. Treatment is the same for whatever is the cause of hypothyroidism - replacement thyroid hormone - Levothyroxine.

When Hashimoto's is present (the name patients generally use for autoimmune thyroid disease) symptoms and test results can fluctuate.

Some members with Hashi's have found that a gluten free diet can help, as can supplementing with selenium l-selenomethionine 200mcg.

Hashi's can cause gut and absorption problems which may result in low nutrient levels or deficiencies.

As for your results, please ignore "normal" and "optimal" that Thriva say, they are nonsense. Please add the actual reference ranges which you will find on the pdf that you can access when you log into your Thriva account. Their help page will tell you how to access the pdf if you haven't already found it. Or from the graphic with the coloured bars the reference range is just the green part (light and dark green) for example the range for FT4 is 12-22.

The range for Ferritin is 13-150 and yours at 48 is low, nowhere near optimal so you can see how nonsensical their descriptions are. Some experts say that the optimal Ferritin level for thyroid function is 90-110ug.

[Krin in reply to SeasideSusie]

Thanks so much for your time and help! I’m worried I thought I just had a underactive thyroid not hashimotos too! What do I do to get these levels down??? As they so high! It would be super hard for me to go gluten free! But to be honest I don’t have much gluten intake anyways apart from weekends wen I have whole meal bread.Will those supplements help?? Or will it interfere with my thyroxine.

So will my results go up and down I can’t keep track of where I am!

Is it still safe to try for a baby?

Thanks Krina

[SeasideSusie Remembering in reply to Krin]

Krin

I’m worried I thought I just had a underactive thyroid not hashimotos too! What do I do to get these levels down??? As they so high!

The TPO antibody level isn't actually that high, we see levels over 1000. They fluctuate, they may go higher, they may go lower, it's just the nature of Hashi's. You can't control the levels but, as I said, some people find that a gluten free diet helps (although it must be strictly gluten free) and some people have said that selenium helps reduce the numbers. It's not the antibodies that are the problem, whilst you have Hashi's it's the immune system attacking the thyroid and the antibodies are there to sort of mop up the mess after an attack. I don't know the exact science (I don't have Hashi's) so maybe someone else will come along and explain.

In the meantime the following articles may help:

Gluten/thyroid connection: chriskresser.com/the-gluten...

stopthethyroidmadness.com/h...

stopthethyroidmadness.com/h...

hypothyroidmom.com/hashimot...

thyroiduk.org.uk/tuk/about_...

The selenium wonti nterfere with your thyroxine, in fact it's said to help with conversion of T4 to T3.

So will my results go up and down I can’t keep track of where I am!

Yes, when the Hashi's is active, you might expect swings from a "false hyper" to hypo to stable. You will get to understand the symptoms.

Is it still safe to try for a baby?

For conception and a successful pregnancy, TSH needs to be below 2.5 and that's with or without Hashi's being present.

[Krin in reply to SeasideSusie]

Thanks so much again for your time really appreciate it! I might give the supplements a try! Never thought my thyroid was hashi’s! I was ill when I gave blood does that count for the results? Luckily my Tsh is 1.33 so will try again this month as I’ve only been on 75mcg levo for six weeks now

Thanks so much

[SeasideSusie Remembering in reply to Krin]

We should not do thyroid tests during or for a few weeks after an acute illness as this can give false results. Always wait for a few weeks after an acute illness has cleared up.

[Krin in reply to SeasideSusie]

Yeah because I had a slight cough and cold when I took the test! I will wait until I’m better to do again! Hopefully I don’t have hashimotos then as my mum and sister don’t have it they have underactive thyroid same as me! And to be honest most of the time I feel good tired as I have a 2 year old. Thanks you have been most helpful

[SeasideSusie Remembering in reply to Krin]

Hopefully I don’t have hashimotos then as my mum and sister don’t have it they have underactive thyroid same as me!

Yes you very likely do have Hashi's, it wont be the antibodies test affected by acute illness, it's the TSH that can be elevated due to acute illness. Over range antibodies suggest Hashi's.

[eeng]

I have seen TPO antibody results as high as 1300. 131 is not really something to be very worried about. I think mine were over 300 when I was diagnosed. They can fluctuate quite a lot too. It looks to me as though your thyroid results are where you would want them to be to conceive. Hope it happens soon for you.

[Krin in reply to eeng]

Thanks so much for your lovely message! You have put a smile on my face as I’ve been so up and down! I needed that positivity! Thanks so much means a lot to me xx

[PDS1]

Dear Krin,Apologies for delay in getting back to you.

I'm not knowledgeable enough to give you advice. It would be wrong for me to even think of doing so.

There are many experts qualified by walking the walk and having spent years researching all things thyroid. SeasideSusie is one of the best.

I wish you the best of health before, during and after your pregnancy.

Good luck and best wishes

PDS1