Thriva results- can anybody assess please

[Onedge]

Active b12 59 pmol/l. (118-701)

Ferritin 40 ug/l (30-370)

Folate 45 nmol/l (6.8-29.5 or 4.5-45.3)

TSH 1.06 (0.27-4.2)

Ft4 16.5 pmol/l (12-22)

Ft3 3.6 pmol/l (3.1-6.8)

Tpoab 6 KIU/l (0-34)

T4 98 nmol/l (57-148)

TgAB 13.3 KU/l (0-115)

Vit D 125 nmol/l (50-200)

I’ve been on Levothyroxine since 2018 when TSH was over range and T4 under range. Since then my TSH has gone up to over range ( doubled dose) then it’s been going down to 2.5,1.6 and now 1. I feel I’m more hyperthyroid than hypo. My vit d and folate are average although I’ve been on daily supplements fir 12,5 years respectively. My b12 and ferritin seems low. Also ate all the other thyroid results typical of thyroid treatment or are they not as optimum as they should be. I would welcome any help as to how to make sense of these results and what to do next

Many thanks

[SeasideSusie Remembering]

Onedge

Thriva have a very confusing way of reporting their results and it looks like you have taken the ranges from their bar graph with the coloured parts. They also have their own nonsensical interpretation of "optimal".

Please log into your Thriva account and find your pdf of results which will look like this

healthunlocked.com/thyroidu...

and the pdf will show the proper reference ranges.

This is the link in their Help page where you can access your pdf

intercom.help/thrivahelpcen...

From what I know of their ranges I can interpret them as follows:

Active b12 59 pmol/l. (118-701)

I think the range for this is 37.5-188 but it may have changed to 25.1-165 but it doesn't really matter.

Active B12 below 70 suggests testing for B12 deficiency according to Viapath at St Thomas' Hospital:

viapath.co.uk/our-tests/act...

Reference range:>70. *Between 25-70 referred for MMA

There is a link at the bottom of the page to print off the pdf to show your GP.

Do you have any signs of B12 deficiency – check here:

b12deficiency.info/signs-an...

b12d.org/submit/document?id=46

If you do then list them to discuss with your GP and ask for testing for B12 deficiency and Pernicious Anaemia. Do not take any B12 supplements or folic acid/folate/B Complex supplements before further testing of B12 as this will mask signs of B12 deficiency and skew results.

Ferritin 40 ug/l (30-370)

Are you male? The male range is usually 30-400. The female range is generally 13-150 or may be 15-300. Whichever it is your ferritin level is low. Ferritin is recommended to be half way through range although some experts say the optimal level for thyroid function is 90-110.

Folate 45 nmol/l (6.8-29.5 or 4.5-45.3)

The range for this used to be 8.83-60.8 so if it's still the same then your level is fine.

TSH 1.06 (0.27-4.2)

Ft4 16.5 pmol/l (12-22)

Ft3 3.6 pmol/l (3.1-6.8)

The aim of a treated Hypo patient on Levo only, generally, is for TSH to be 1 or below with FT4 and FT3 in the upper part of their reference ranges.

Did you do this test as we advise, i.e. no later than 9am, nothing to eat or drink except water before the test, last dose of Levo 24 hours before the test? If so then you are undermedicated as your FT4 is only 45% through range and your FT3 is only 13.5% through range.

Tpoab 6 KIU/l (0-34)

T4 98 nmol/l (57-148)

TgAB 13.3 KU/l (0-115)

Thyroid antibodies are nice and low so don't suggest autoimmune thyroid disease, known to patients as Hashimoto's, with those lelvels. I haven't commented on Total T4 as it's not a particularly useful test, it's the FT4 which tells us what we need to know.

Vit D 125 nmol/l (50-200)

The Vit D Society and Grassroots Health recommend a level of 100-150nmol/L. Yours is nicely mid-range

[Onedge]

Hi Seaside Susie

Thanks for your brilliant feedback. I think from all the test results I’ve had back over the years it’s all showing the same thing. Very low or deficient results

Folate - severe deficiency

Vit d - severe deficiency

Thyroid- severe deficiency

Oestrogen- severe deficiency

Testosterone- severe deficiency

Now vit b12 and ferritin.

Also, I took a check my health test using my hair and it came back with lots of sensitivities to all breads except rye, all dairy, etc. The interesting result was I had no enzymes ( can’t remember them now but amylase was one) that showed I can’t break down fats, carbohydrates or proteins. It just all makes sense that my gut problems of absorption and my cell uptake problem are causing all my problems.

Thank goodness for your reply as I now need to buck up courage and go and see my doctor.

Kind regards and I’ll let you know how I get on. Thanks

[Onedge]

I think I’ve replied to myself!! Can you look at the second reply to my initial question as it is to you. Also, your email encouraged me to contact the doctor who is booking some more tests and thinks supplementing with b12 should be done. Just have to wait til I next speak to the endocrinologist about my thyroid results. Thank you and I’ll text again hopefully with some answers

[SeasideSusie Remembering in reply to Onedge]

Onedge

Yes, you replied to yourself which doesn't send me a notification.

Can you look at the second reply to my initial question as it is to you.

Sorry, where is it?

[Onedge]

I’m not sure how to reply to you other than pressing the reply button which then seems to go back to me. I think I’ve tried to message you separately but not sure if that worked either. Please help!! I’m useless with technology

[SeasideSusie Remembering in reply to Onedge]

Onedge

To reply to a member's message so that they get a notification you click on the blue REPLY box directly beneath their post, you will then see Reply to XXXX (member's name) above the box you out your message in. It indents your message below the message you are replying to, as you can see with this reply to you.

You asked me

"Can you look at the second reply to my initial question as it is to you."

But I can't see where it is.

[Onedge in reply to SeasideSusie]

I did that first time and I’ve done this before on old conversations but it just didn’t work this time

[SeasideSusie Remembering in reply to Onedge]

OK I think you mean the reply you did above that you did to yourself. Sorted!