Started T3 trial, have added Cortisol results to blood results, appreciate some guidance 🙏

[jamjar67]

Results when taking 125/100 Levo alternative days

Blue Horizons

‭06-Aug-20 8:30 AM‬

‭(NB I had a 6 month break from B12 to get a real reading, also had a total Vit break for a couple of months - following these results I am now supplementing again)‬

TSH 0.04 (0.27 - 4.2)

FT4 23.2 (12 - 22)

FT3 4.59 (3.1 - 6.8)

T4 Total‭ 123.0 ‬66 - 181‭ ‬nmol/L

hs-CRP‭ 0.63 <5.0 mg/L‬

Ferritin‭ 112.0 13 - 150 ug/L‬

Magnesium‭ 0.99 0.7 - 1.0 mmol/L‬

Vitamin D (25 OH)‭ ‬

‭59 50 - 175 nmol/L‬

Vitamin B12‭ 481 ‬

Deficient <145‭ ‬pmol/L

Insufficient 145 - 300

Consider reducing dose >569

Serum Folate‭ ‬

‭18.90 ‬8.83 - 60.8‭ ‬nmol‭ ‬

Cortisol (Random)‭ ‬

‭373.0 ‬

‭6am - 10am 113 - 456 nmol/L‬

4pm - 8pm 58 - 278

Midnight <64

Anti-Thyroidperoxidase abs‭ H 276 ‬<34‭ kIU/L‬

Anti-Thyroglobulin Abs‭ H 257 ‬<115‭ kIU/L‬

Monitor My Health 14/9/20 8am

(Did this test as I messed my hospital test up accidentally taking biotin beforehand)

FT3 4.8 (3.1 - 6.8 )

FT4 21.3 (12 - 22 )

TSH 0.05 (0.27 - 4.2 )

Here are my recent Cortisol results (photo attached)

(I had dropped my Levo to 100mcg per day for just a few days before this test)

Starting NHS T3 trial

Dropped Levo to 100/75mcg for a week

Dropped to 75mcg for 4 days (had to do this as the Endo prescribed me for 75mcg to start T3 trial so no 100,s left)

On 29th Sept added in 2.5mcg of T3 at 7am and 2.5 at 5pm

On Fri 2nd Oct - 5mcg at 7am and 2.5mcg at 5pm

Interestingly, after initially lowering my Levo I felt very tired/wiped out asleep at 8.30 pm and slept well until about 4am

Initially Adding T3 - I felt quite good, however this last 2 days have started to feel ropey again, cold, the weird chemistry feeling in my skin is more prominent and feeling drained (feel it around my eyes) aching joints, my head though feels a bit clearer!, although I still have the boat like sensation in my head I feel it’s improved (it’s early days and I’m trying not to be too hopeful. Also I haven’t had any heart flutters so far which I was getting with Levo 100/125 🤞

I’m just unsure what to do from here and based on my cortisol do you think I’m taking the T3 at the right times ? 🤔. I thought maybe after a few more days doing 5 and 5, but basically I still feel ‘not right’

I read something by Paul Robinson which explains taking T3 - saying enough of the waves must hit the rock so the spray can reach the beach- thinking of it this way I’m guessing I probably need more T3 although I know my vits need sorting out so my body can use the T3 - just not sure what to do next?

I am supplementing Vit D with A

B vits (Igneus super B)

B12

Odd iron tablet and chicken liver pate here and there

Vit C in the morning

Any guidance appreciated - Thank you

[SlowDragon Administrator]

Testing should only be done after 6-8 weeks on constant unchanging dose levothyroxine and T3

Which brand of levothyroxine were you taking when on 100mcg

Are you currently taking Teva brand at 75mcg?

Important to stop vitamin B complex a week before any blood tests - did you do that for MMH test?

Are you planning on adding 3rd 5mcg dose of T3?

You will need to test TSH, Ft4 and Ft3 again 6-8 weeks after adding last increase in T3

It typically takes many months to settle on Levo plus T3

[jamjar67 in reply to SlowDragon]

Which brand of levothyroxine were you taking when on 100mcg

Mercury Pharma

Are you currently taking Teva brand at 75mcg?

No - 50+ 25 of Mercury Pharma

Important to stop vitamin B complex a week before any blood tests - did you do that for MMH test?

No - I was eating well thru lockdown and wanted to see how well my body was absorbing vits from food/sunshine (Vit D)

Are you planning on adding 3rd 5mcg dose of T3?

I don’t really want to at this stage as I find it difficult enough fitting 2 doses around food, supplements - next step was to up my 2nd dose to 5mcg ?

You will need to test TSH, Ft4 and Ft3 again 6-8 weeks after adding last increase in T3

I was just wondering if I should up the dose to 5 + 5 and then wait 6 weeks? I’ve had no reaction to T3, (I was worried about anxiety but am ok so far)

The other thing - I was contemplating taking my T3 with my T4 when I wake at 4am and my 2nd dose before lunch about 12.30 ? Then I suppose I would feel it if I need a 3rd dose 🤔

As always, Thankyou for your input 😊

[SlowDragon Administrator in reply to jamjar67]

Good you are still on same brand of levothyroxine

Yes you could add T3 alongside levothyroxine at 4am ...likely to find you get lovely deep sleep

Increase 2nd dose to 5mcg ....approx 12 hours later

If adding 3rd 5mcg dose in couple of weeks (or later)

Change gap between doses to 8hours

So 4am, noon and 8pm

(Or might be easier to fit around food at 6am, 2pm and 10pm)

I take my levothyroxine at night so that I don’t have to worry about breakfast and levothyroxine

So time doses as 7am, 3pm and 11pm

[jamjar67 in reply to SlowDragon]

Yes you could add T3 alongside levothyroxine at 4am ...likely to find you get lovely deep sleep

So I did this last night, slept awful, the weird chemistry feeling in my body was bad (I’m suspecting this could be related to Oestrogen dominance (I’m homozygous COMT and Endo said my oestrogen is very high) or cortisol ) - I’m on the Mirena coil however I feel I ovulated 2 days ago and had light spotting for the 1st time in over a year yesterday ) anyway am keeping a diary to see if there’s a pattern. Also my temp is slightly low so prob still undermedicated, so it could just be that 🤷‍♀️ On a plus my boat like head feels quite good this morning (I don’t want to speak too soon, but this is hopeful!!!!🤞)

Think I’ll try 2 x 5mcg doses today so next at 4.30 pm

I take my iron last thing so it doesn’t interfere with anything.

Anyway, I’ll do this for a few days and monitor things.

Thanks again x