First bit of background. Strong family link to thyroid and hashimoto on my mothers side of family so I’ve always been curious about various symptoms but never sure if this was down to being a shift worker or an actual thyroid problem. Many years ago got tested at dr all back normal range but was convinced to see Dr Peatfield Durrant who was treating my mother and said no definitely a thyroid problem. Never followed up much to my regret. Having seen what my mother has gone through last few years and reading an article on hashimotos I recognised some symptoms in myself and thought must get it all checked. Last October I purchased medicheck thyroid ultra plus vit and I have just done another one few days ago and wanted some help understanding the changes in results of tests taken 9 months apart
17th Oct 2019
CRPHS 0.95 mg/l range <5
Iron 21.2 ug/l 13-150
B12 77.1 pmol/l range >37.5
Vit D 18.3 nmol/l range 50-175
TSH 4.18 mlU/l range 0.27-4.2
Free T3 5.51 pmol/l range 3.1-6.8
Free thyroxine 15.3 pmol/l range 12-22
Thyroglobulin antibodies 420 klU/l range <115
Thyroid Peroxidase antibodies 356 klU/l range <34
28th Jul
CRPHS 1.57 mg/l range <5
Iron 25.2 ug/l 13-150
B12 94.5 pmol/l range >37.5
Vit D 40.5 nmol/l range 50-175
TSH 1.17 mlU/l range 0.27-4.2
Free T3 3.89 pmol/l range 3.1-6.8
Free thyroxine 13.7 pmol/l range 12-22
Thyroglobulin antibodies 321 klU/l range <115
Thyroid Peroxidase antibodies 277 klU/l range <34
I have occasionally taken B sups and vit D which I can see increased from last year but trying to figure out the decrease in antibodies and thyroid
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Jem23926
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Eating iron rich foods like liver or liver pate once a week plus other red meat, pumpkin seeds and dark chocolate, plus daily orange juice or other vitamin C rich drink can help improve iron absorption
This is interesting because I have noticed that many patients with Hashimoto’s disease and hypothyroidism, start to feel worse when their ferritin drops below 80 and usually there is hair loss when it drops below 50.
October test was about 8am before food but the July 2020 one was in afternoon. Was too eager to get it done when kit arrived. Only sparodically taking oral spray one for iron and other multi bit both better you brand but hadn’t taken any in the week beforehand. Was on a high dose B vit for couple of months but I am really bad at remembering to take or take at same time of day with shift patterns
I’m just starting to look at nuti advance supplements to see if they can help
As you have Hashi's, your levels are going to jump around. But, to be able to compare them in any meaningful way, you have to do all tests under the same conditions: preferably early morning and fasting.
So, impossible to compare the two TSH because TSH is highest early morning, and drops thoughtout the day. But, what is important is the way our FT3 has dropped. You are clearly hypo, now.
Not point in even retesting antibodies, certainly not fretting over the difference in levels, as it doesn't mean anything. A high reading tells you you have Hashi's, and Hashi's doesn't go away, no matter what the antibodies do. And, they fluctuate.
Thank you for the advice. I’d booked a blood draw from local centre for second one rather than losing four fingers again to a prick test version of kit. Now understanding the importance of time the blood was drawn I shall plan bit more carefully
As GG says...always do test early morning before eating or drinking anything other than water
Hashimoto's frequently affects the gut and leads to low stomach acid and then low vitamin levels
Low vitamin levels affect Thyroid hormone working
Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.
According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)
Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies
While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first
Assuming test is negative you can immediately go on strictly gluten free diet
(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)
Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse
The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported
In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned
Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.
Suggest you spend next 2-3 months improving vitamin levels and then retest again
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