Took advantage of Medichecks Thyroid Ultravitamin offer, after I requested antibody testing from my GP, and it was ignored.
My results came through last evening 9.12.19:
CRPHS. 1.43 mg/L. (Within range <5)
Ferritin. 45.2. ug/L. ( “. 13-150)
Folate serum. 6.86ug/L. ( “. 3.89 -19.45)
Bit B12 Active. 111pmol/L. ( “ 37.5-187.5)
Vit D. 54.8 nMol/L. (“. 50-175). *
TSH. 0.034 mIU/L. (Outside range)
Free T3. 5.15 pmol/L. (Within range 3.1 - 6.8)
Free T4. 25.1 pmol/L. (Outside range)
Thyroglobulin antibodies. 413kIU/L. (Outside range of up to 115)
Thyroid Peroxidase A/b. <9. (Range <34)
Context: no Levothyroxine since 24 hours prior to testing. Vit B in low range four months earlier but treated with S/l drops, which discontinued 18 days prior to testing.
No Hyperthyroid signs. Eyes still quite hard to open, low pulse and body temp always 35.8 deg C. Low energy, some spots on skin, dry skin and hair, headaches and exhaustion when very active.
Sorry to bombard you with all this, but know my GP will just send me away again. Have never been to an endo in 7 years since diagnosis, but reacted very badly when dose reduced dramatically and suddenly in 2018.
Thanks so much!
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BlueMoon65
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Vit B in low range four months earlier but treated with S/l drops, which discontinued 18 days prior to testing.
Can you please clarify which this is - Vit D or B12 or a B Complex? Whichever it was there was no need to discontinue supplementing for 18 days before testing.
CRPHS. 1.43 mg/L. (Within range <5)
This is OK, it's an inflammation marker and fairly low in range.
Ferritin. 45.2. ug/L. ( “. 13-150)
This is on the low side. Ferritin s recommended to be half way through range. You can help raise your level by eating liver regularly, maximum 200g per week due to it's high Vit A content, also liver pate, black pudding, and including lots of iron rich foods in your diet
This is on the low side. Folate is recommended to be at least half way through range. Eatling lots of folate rich foods can help, as can a good quality B Complex such as Thorne Basic B, Igennus Super B or maybe a Whole Food B Complex.
Bit B12 Active. 111pmol/L. ( “ 37.5-187.5)
This is fine. Is this what you are supplementing? If so, how much?
Vit D. 54.8 nMol/L. (“. 50-175).
This is too low. The Vit D Council/Vit D Society recommend a level of 100-150nmol/L. To reach this level from your current level it's suggested to supplement with 4,000-5,000iu D3 daily. Retest after 3 months.
When you've reached the recommended level then you'll need a maintenance dose to keep it there, which may be 2000iu daily, maybe more or less, maybe less in summer than winter, it's trial and error so it's recommended to retest once or twice a year to keep within the recommended range. You can do this with a private fingerprick blood spot test with an NHS lab which offers this test to the general public:
Doctors don't know, because they're not taught much about nutrients, but there are important cofactors needed when taking D3 as recommended by the Vit D Council
D3 aids absorption of calcium from food and K2-MK7 directs the calcium to bones and teeth where it is needed and away from arteries and soft tissues where it can be deposited and cause problems such as hardening of the arteries, kidney stones, etc.
D3 and K2 are fat soluble so should be taken with the fattiest meal of the day, D3 four hours away from thyroid meds if taking tablets/capsules/softgels, no necessity if using an oral spray.
Magnesium helps D3 to work. We need Magnesium so that the body utilises D3, it's required to convert Vit D into it's active form. So it's important we ensure we take magnesium when supplementing with D3.
Magnesium comes in different forms, check to see which would suit you best and as it's calming it's best taken in the evening, four hours away from thyroid meds if taking tablets/capsules, no necessity if using topical forms of magnesium.
Check out the other cofactors too (some of which can be obtained from food).
TSH. 0.034 mIU/L. (Outside range)
Free T3. 5.15 pmol/L. (Within range 3.1 - 6.8)
Free T4. 25.1 pmol/L. (Outside range)
no Levothyroxine since 24 hours prior to testing.
The aim of a hypo patient generally, when on Levo, is for TSH to be 1 or below or wherever it needs to be for FT4 and FT3 to be in the upper part of their reference ranges, if that is where you feel well.
How much Levo are you taking?
It seems as though you need an over range FT4 to achieve a mid-range FT3 which can suggest poor conversion of T4 to T3.
Optimising all your nutrient levels can help so improving Ferritin, Vit D and Folate are a priority. Once at optimal levels, if conversion is still poor maybe consider adding T3 to your Levo.
Thyroglobulin antibodies. 413kIU/L. (Outside range of up to 115)
Thyroid Peroxidase A/b. <9. (Range <34)
Raised Thyroglobulin antibodies can suggest autoimmune thyroid disease (Hashimoto's) even when Thyroid Peroxidase antibodies aren't raised, but there are other reasons for raised Tg antibodies. However, my guess would be that you have Hashi's so you could try a strict gluten free diet and supplementing with selenium l-selenomethionine 200mcg daily to see if they help (some people prefer to test selenium before supplementing). Although there is no guarantee some members have found that gluten free diet does help.
Gluten contains gliadin (a protein) which is thought to trigger autoimmune attacks so eliminating gluten can help reduce these attacks.
You don't need to be gluten sensitive or have Coeliac disease for a gluten free diet to help.
So like many, many autoimmune thyroid patients you only have raised TG antibodies. Currently NHS refuses to acknowledge high TG antibodies is Hashimoto's
Hashimoto's frequently affects the gut and leads to low stomach acid and then low vitamin levels
Low vitamin levels affect Thyroid hormone - so following Seasidesusie recommendations on how to improve
Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.
According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)
Changing to a strictly gluten free diet may help reduce symptoms, help gut heal
While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first
Assuming test is negative you can immediately go on strictly gluten free diet
(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)
Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse
Non Coeliac Gluten sensitivity (NCGS) and autoimmune disease
The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported
In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned
Vitamin D deficiency is frequent in Hashimoto's thyroiditis and treatment of patients with this condition with Vitamin D may slow down the course of development of hypothyroidism and also decrease cardiovascular risks in these patients. Vitamin D measurement and replacement may be critical in these patients.
Evidence of a link between increased level of antithyroid antibodies in hypothyroid patients with HT and 25OHD3 deficiency may suggest that this group is particularly prone to the vitamin D deficiency and can benefit from its alignment.
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