Suprising test results.................
yet I still feel awful
My Medichecks results arrived this afternoon, they are as follow
THYROID STIMULATING HORMONE *0.206 mIU/L 0.27 - 4.20
FREE THYROXINE 19.5 pmol/L 12.00 - 22.00
TOTAL THYROXINE(T4) 119.0 nmol/L 59.00 - 154.00
FREE T3 4.93 pmol/L 3.10 - 6.80
THYROGLOBULIN ANTIBODY *890.000 IU/mL 0.00 - 115.00
THYROID PEROXIDASE ANTIBODIES*>600 IU/mL 0.00 - 34.00
VITAMIN B12 *777 pmol/L 140.00 - 724.00
FOLATE (SERUM) 19.98 ug/L 2.91 - 50.00
Inflammation MarkerCRP - HIGH SENSITIVITY 0.1 mg/l 0.00 - 5.00
FERRITIN 54 ug/L 13.00 - 150.00
The comments/advice was
We note that you are taking this test to investigate symptoms. I understand that you have an underactive thyroid and that you have been taking 25mcg of levothyroxine for the past ten years. You continue to experience lethargy, gritty eyes, ear problems, joint pains, palpitations, pins and needles, dizzines, brain fog, low body temperature and new onset acid reflux. I understand that you struggle to swallow your own saliva and that you have lost two stone in weight.
Reviewing your symptoms I am concerned by the recent development of acid reflux, swallowing difficulties and loss of weight. I recommend that you discuss these promptly with your GP as these are likely to need further investigation.
Your thyroid stimulating hormone is low whilst you have normal levels of thyroxine and T3. This suggests that your dose of levothyroxine is too high. If you are free of symptoms of an overactive thyroid then you may prefer to repeat the test in three months to assess the trend. If you are experiencing symptoms then you should discuss this result with your GP.
Having very low levels of thyroid stimulating hormone for several years has been associated with the development of osteoporosis. If your thyroid stimulating hormone always tends to be substantially below the normal range then it may be worth discussing with your GP whether a bone density scan is advised to monitor for the development of osteoporosis. You do not need to worry about the occasional low reading, only if you get repeated very low levels.
Your thyroglobulin antibodies are positive. This can be associated with autoimmune thyroid disease and in particular Hashimoto’s disease.
Your thyroid peroxidase antibodies are elevated. This antibody is commonly associated with autoimmune thyroid disease. It is frequently seen in conditions such as Hashimoto’s disease (where the thyroid becomes underactive) but confusingly can also be seen in Grave’s disease (where the thyroid becomes overactive).
You have high levels of vitamin B12, if you are taking a B12 supplement then I recommend decreasing your dose. If you are not taking a supplement then I recommend checking your full blood count and liver function to assess whether this is significant.
You have normal levels of folate.
Your CRP level is normal, suggesting low levels of inflammation within the body.
Your ferritin level is normal indicating healthy iron stores.
My NHS ones which I got this morning are
Thyroid function test-Abnormal
For primary hypothyroidism,levothyroxine replacement should be targeted toward a TSH within the reference range,after dose adjustments allow 8 weeks to stabilise.
Serum TST level 0.09 mU/L 0.35-5.50 mU/L
serum T4 level 13 pmol/L 7.00-17.00pmol/L
I have absolutely no idea what is going on, my symptoms are the same and i do not experience any hyper symptoms, the only change I have made is when I take the Levothyroxine, a week ago I started taking it at night with water and not in the morning with my multivitamins etc, still the same dose 25mcg, I can't understand why my levels have changed but not the horrible symptoms.Last tests results were
Serum TSH Levels 3 mU/L 0.35-5.50mU/L
, Serum free T4 level 10.9 pmol/L 7.00-17.00pmol/L October 2017.