Blood results back - help needed :)

Hello everyone,

I have just received my adrenal stress profile from Genova and my cortisol is high in the morning, at lunchtime and late afternoon. Evening is normal, but top range.

DHEA 0.12 (0.05 - 0.32)

I have Hashimoto's, my antibodies did fall from almost 1000 to 880.

TSH < 0.01 (I'm on Nature Throid, 3 grains)

FT3 = 6.5 (3.1 - 6.8) fasting for 24 hours, I took 3 grains at once in the morning

TT3 = 2.2 (1.3-3.1)

FT4 = 19.4 (12 - 22)

Vit B12 = 440 (197-771)

Vit D = 85 (30-125) - on 4000 units of vit D for 2.5 weeks at that point

Ferritin = 34 (13-150) - on iron supp for 2.5 weeks at that point

My symptoms right now: acne/oily/dull skin, pale lips, extreme fatigue and brain fog (can barely read sometimes or focus on screen), lost weight (but now is more less stable), muscle twitches, left foot vibrating, whole body tremor, insomnia/waking up at 3-4 am and with high pulse, low blood pressure, indigestion/low stomach acid, food sits in the belly area, shortness of breath from time to time and racing thoughts/high stress

Background: been on 4 grains of Nature Throid until April; my bloods in April were:

TSH = 0.03, FT4 = top range, TT3 = top range, no FT3 measured; felt mostly fine and full of energy; GP told me to reduce from 4 to 3 grains based on TSH. 3 months later started to get palps flushes after steroid/antibiotics, GP reduced and stopped Nature Throid for about 4 weeks (alarmed by low TSH ), then started on 3 grains again (without incremental increase!). Needless to say - I have not felt right since - a lot of strange symptoms of hypo/hyper/stress.

10 days ago I reduced meds by 1/2 grain to 2.5 a day and I can safely say now I feel more sluggish, more brain fog, more tiredness, still high pulse and still cannot sleep etc.

Questions:

1) Could it be that after 10 days I already see the difference in reduction? Or should I stay on 2.5 grains for longer?

2) Is it safe to increase by 1/2 grain every 2 weeks up to 4 grains to see if there is any improvement (I felt great on 4 grains before)?

3) Hormonal resistance? Should I take more hormones during stress - or should I add t3 (I have a pack of Thybon at home...) to NDT? If so, how much?

I did see an new endo yesterday and he thinks this is pure stress and was told to exercise, meditate, tai chi etc, which I will do, but I honestly wonder if I need to increase my hormones.

Endo wants me on 2.5 grains for another 4 weeks, but was not alarmed by low TSH (thankfully).

So many questions Did anyone go through something similar?

Thanks so much!

Tunia

[Clutter]

Tunia,

Why did you reduce dose to 2.5 grains? TSH is suppressed but FT4 and FT3 are within range so you weren't overmedicated on 3 grains. I suspect 4 grains will overmedicate you because FT4 and FT3 are close to top of range on 3 grains.

B12 440 is unlikely to be deficient but if you have symptoms in b12deficiency.info/signs-an... go to healthunlocked.com/pasoc for advice.

VitD is optimal 100 - 150 so I would continue supplementing D3. Make sure you take vitD 4 hours away from NDT.

You do not have hormone resistance and do not need to supplement T3 when you feel stressed.

High thyroid peroxidase antibodies are positive for autoimmune thyroid disease (Hashimoto's). There is no cure for Hashimoto's which causes 90% of hypothyroidism. NDT treatment is for the low thyroid levels it causes. Many people have found that 100% gluten-free diet is helpful in reducing Hashi flares, symptoms and eventually antibodies.

chriskresser.com/the-gluten... G-F may also ease your indigestion and improve digestion.

thyroiduk.org.uk/tuk/about_...

You can raise stomach acid by taking Betaine Pepsin before meals or raw apple cider vinegar in fruit juice or honey-sweetened water before meals.

I can't advise how to deal with high cortisol. If you don't get more replies write a new post with your DHEA and cortisol results and ask for advice. You can also type "high cortisol" into the Search Thyroid UK box to see previous posts on the subject.

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Thank you so much @clutter !

I reduced to see if maybe insomnia and other symptoms were from going over the range. Ft3 was so close to the top I was worried.

I have been previously on 4 grains and felt amazing with ft4 22 (12-22) and t3 3.1 (1.7-3.1) and TSH 0.03. How this could be? Ft3 was not tested at the time, but I am positive it must have been then over the range?

I also understand thay high chronic stress might be causing this havoc! I experience a huge fatigue, makes me unable to go to work