Interpreting Results

[JTaberer]

Hi, my results always come back within range, but I have symptoms and have some relevant genetic mutations. These are the most recent results from July

ENDOCRINOLOGY

TOTAL THYROXINE(T4) 108 nmol L 59 - 154

THYROID STIMULATING HORMONE 1.98 mIU L 0.27 - 4.2

FREE THYROXINE 15.1 pmol 12.0 - 22.0

FREE T3 4.4 pmol L 3.1 - 6.8

25 OH Vitamin D 105 nmol L 50 - 200

Interpretation of results:

Deficient <25 nmol/L

Insufficient 25 - 49 nmol/L

Normal Range 50 - 200 nmol/L

Consider reducing dose >200 nmol/L

IMMUNOLOGY

THYROID ANTIBODIES .

Thyroglobulin Antibody 10.9 IU mL 0-115

Method used for Anti-Tg: Roche Modular

Thyroid Peroxidase Antibodies 10.1 IU mL 0 - 34

Method used for Anti-TPO: Roche Modular

These were all reported as normal, would you agree?

I have these genetic mutations:

CTLA4 Thr17Ala G AG +/-

rs1867277 FOXE1 5378A>G A AA +/+

rs10984009 FOXE1 8124G>A A GG -/-

I have constiptation most of the time, my hair falls out more than usual every so often, i have itchy skin, weight gain/difficulty loosing weight etc

Any advice would be appreciated.

Thanks

Julie

[Clutter]

JTaberer,

TSH, Free thyroxine (FT4) and Free T3 are euthyroid (normal) and thyroid antibodies are negative for autoimmune thyroiditis (Hashimoto's). You don't appear to have thyroid dysfunction.

I don't know what those gene mutations are. Perhaps you can Google them for more information.

You could try a 100% gluten-free diet to see whether constipation and itchy skin improve. Give it a couple of months and if there is no improvement you may as well reintroduce gluten.

Ask your GP to check ferritin, vitamin D, B12 and folate. Low ferritin/iron commonly causes hair loss.

[JTaberer in reply to Clutter]

Hi, thank you, i think the genes relate to some form of thyroid dysfunction from what I can remember which was why I was querying the results, was both vit b12 and vit d deficient, injections and tablets have corrected the deficiencies