Confused!

Hi, Wondered if anyone could help with my results. I went to GP who diagnosed Overactive Thyroid from a routine blood test. I have no symptoms so had a blood test done from medicheck and this is the result but i am clueless. Many thanks in advance!

THYROID STIMULATING HORMONE *0.02 mIU/L 0.27 - 4.20

FREE THYROXINE *27.21 pmol/L 12.00 - 22.00 TOTAL

THYROXINE(T4) *163.4 nmol/L 59.00 - 154.00 FREE T3 4.35 pmol/L 3.10 - 6.80

Thyroid AntibodiesTHYROGLOBULIN ANTIBODY *208.400 IU/mL 0.00 - 115.00

THYROID PEROXIDASE ANTIBODIES*58.71 IU/mL 0.00 - 34.00

I also had this from the doctor at medichecks.

We note that you are taking this test to monitor your over-active thyroid.

You have low thyroid stimulating hormone with high levels of free and total thyroxine.

You have normal free T3.

Your thyroid peroxidase antibodies are elevated. This antibody is commonly associated with autoimmune thyroid disease. It is frequently seen in conditions such as Hashimoto’s disease (where the thyroid becomes underactive) but confusingly can also be seen in Grave’s disease (where the thyroid becomes overactive).

Your thyroglobulin antibodies are positive. This can be associated with autoimmune thyroid disease and in particular Hashimoto’s disease.

I recommend that you discuss these results further with your GP.

5 Replies

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  • minnie

    You have Hashimotos Autoimmune Disease which is common in hypothyroidism but your results show you as hypERthyroid.

    It is possible to have elevated TGAb and TPOAb with Graves Disease so ask your doctor to test you for TSI antibodies.

    TSI (thyroid stimulating immunoglobulin) antibodies tell the thyroid gland to become more active and so release excess amounts of thyroid hormone. A TSI test measures the amount of thyroid stimulating immunoglobulin in your blood.

    Excessive release of thyroid hormone might bring about an increased appetite, diarrhea, weight loss, rapid heartbeat and heat intolerance.

  • Thanks for the reply but this is all new to me..what is TGAb and TPOAb..my GP told me she had tested for all antibodies and they were normal but the medichecks show the ones tested as not normal...i was put on 20mg of Caribizaole from Gp and then she contacted hospital after 2 days and i was put on 10mg Carbizamole plus 60mg of a beta blocker even though she said my pulse was fine and i have no palpitations so does this mean in simple terms i am hyper but with a hypo disease, sorry if i sound dumb!

  • minnie,

    TPOAb attacks an enzyme found in your thyroid gland called the Thyroid Peroxidase and TGAb attacks the key protein in the thyroid gland called thyroglobulin, both of which causes the gradual destruction of follicles in the thyroid gland.

    Yours are not normal as are elevated.

    Carbimazole will lower the level of thryoid hormone and beta blockers are given to slow the heart rate. Patients are not usually kept on anti-thyroid drugs for more than 18 months - they are offered Radio-iodine treatment or surgery to remove the thyroid.

    I am hypothyroid with Hashimotos, so do not have Graves Disease and can't unfortunately offer you my experiences.

  • Thanks for explaining..i will ask my GP for the tests as you said...appreciate your advice!

  • You might find my abbreviations and acronyms document of some use. It doesn't try to explian, but should help you to identify what they mean:

    dl.dropboxusercontent.com/u...

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