Please I need your help. I'm very confused with my results. I'm now taking 10 mg of Carbimazole.
This was the Medichecks doctor's advice:
Your thyroid stimulating hormone is now high and your free thyroxine and T3 are both low. This suggests that your thyroid is currently under-active and that your dose of carbimazole may need to be reduced. An underactive thyroid can lead to symptoms which includes fatigue and weight gain. Your thyroglobulin antibodies are positive. This can be associated with autoimmune thyroid disease and in particular Hashimoto’s disease. Your thyroid peroxidase antibodies are also elevated. This antibody is commonly associated with autoimmune thyroid disease. It is frequently seen in conditions such as Hashimoto’s disease (where the thyroid becomes underactive) but confusingly can also be seen in Grave’s disease (where the thyroid becomes overactive). I advise discussing this result with your doctor.
I have problems with one of my eye that shows that I have the Grave's disease anyway. Now I have to deal with Hashimoto's also?????
And how T4 changed so quickly to underactive symptoms? With your experience what must be done?
Below are my latest blood test results
Thyroid Hormones
TSH X 4.26 mIU/L (Range: 0.27 - 4.2)
Free T3 X 2.99 pmol/L (Range: 3.1 - 6.8)
Free Thyroxine X 8.440 pmol/L (Range: 12 - 22)
Autoimmunity
Thyroglobulin Antibodies X 1521.000 kIU/L (Range: < 115)
Thyroid Peroxidase Antibodies X 355 kIU/L (Range: < 34)
Thank you all in advance x
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Elenicy
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You need to see GP and ask for referral to Thyroid specialist endocrinologist and carbimazole will need reducing
Both TPO and TG thyroid antibodies are very high. This is more likely due to Hashimoto's. You can have raised TPO or TG antibodies due to Graves, but not usually such high levels
If you only have Hashimoto's and not Graves as well, then carbimazole is not correct treatment
If you do have both Graves and Hashimoto's then you would take carbimazole to "block" and Levothyroxine to "replace"
This needs management by experienced endocrinologist
Clearly your results now show you are hypothyroid
Absolutely essential to get vitamin D, folate, ferritin and B12 tested. These are frequently too low and supplementing to improve can help improve symptoms
Hashimoto's and Graves both affect the gut and can lead to low stomach acid and then low vitamin levels
Low vitamin levels affect Thyroid hormones
Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.
According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)
Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies
While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first
Assuming test is negative you can immediately go on strictly gluten free diet
(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)
Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse
Hi Slowdragon, thank you for your reply. The results I’ve put are from medichecks. My GP has a letter from the eye clinic doctor that suggested a sooner appointment to endocrinologist (I’m booked for 10th October). My GP said that he will try his best to change it.
Hi SlowDragon. That I have Grave's is confirmed from the Maidstone Eye Clinic. (Even they lost my PTO blood test). I booked an appointment for tomorrow morning with my GP.
If it's Hashimoto's that u have right now, then carbimazole is the wrong medicine to be on.
Your eye problem sounds pretty severe. To get it better, the main thing is to correct the underlying condition. If it's Hashimoto's, (and u might have that since your TG and TPO antibodies are still very high), correcting the Hashis will bring relief for your eyes.
Not to be dramatic, but the longer you remain untreated for the Hashis, if it is Hashis, the more damage will be to your eyes. Thyroid eye disease when in the active phase, can progress quite rapidly and do quite a fair bit of damage.
We're not here to pressure you, as I'm sure you are trusting the doctors to order the correct tests for you. They are after all, the professionals.
To be honest, with this you write here, I start now to understand Actually I didn't know that Hashimoto's related with eye problems. Unfortunately the only antibodies test results I have are those I put on this post.
About the comment you did about professionals, antibodies checked private by medichecks because my GP was unable to write them for me with the excuse that he can't do it.
Thanks God and bless you all here for your support.
This I did at medichecks (Thyroglobulin Antibodies and Thyroid Peroxidase Antibodies are different from TSI or TRab? Sorry if it is stupid question. Actually I'm confused
Your link doesn't work because it is a link to the C Drive on your computer. And random people on the internet are not allowed to access that, you'll be glad to hear.
Doesn't suggest Graves. Looks like early stage Hashimoto's
Slightly low TSH, mildly raised FT4. Typical results from small Hashimoto's flare
As advised at the time. These results did NOT suggest Graves
Your GP might have assumed they did, but GP's often know little about thyroid disease
We see many Hashimoto's patients misdiagnosed as Graves......especially if tested in early stages and test happens to catch low TSH
I nearly was misdiagnosed myself. Fortunately my GP ran antibodies testing and TPO were extraordinarily high (over 4,000) .....plus I was lucky my TSH was higher. But he had assumed I was hyper not hypo. I had lost weight too. Common in early stages of Hashimoto's. But with Hashimoto's we are hypothyroid. Even if have temporary hyper mini swings.
Someone having hypothyroid and hyperthyroid symptoms and fluctuating blood test results may have a condition called hashitoxicosis.
1) My understanding of this condition (which is very limited) suggests that the name is sometimes used to describe the hyperthyroid condition that may occur in the early stages of Hashimoto's Thyroiditis.
2) I've also seen it described as a condition in which the patient has antibodies normally found in Hashimoto's Thyroiditis and also in Graves' Disease. I don't know which set of antibodies would be considered to be definitive for hashitoxicosis.
I don't know which of these is the "true" definition. But it would be worth doing some research to see if any of the info out there on the subject is of help to you.
Yes I experienced It . I first was hyperthyroid where I experienced palpitations lost lots of weight . It was followed by hypothyroidism where I gained weight no matter how much I watched my weight exercised. Became lethargic , was cold all the time when others where comfortable tired all the time no energy etc.
I think I might have both ... I haven't had my private blood test yet because I am waiting for a Consultant Endo appointment. At the moment I feel very well .. I have lost 7lbs and my skin and hair look good. I no longer have night sweats and I can smell & taste food again. However, I still have tinnitus so I think this mustn't be connected with my thyroid disease. I think I am in remission again but I have no idea how long it will last this time.
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Actually I didn't know that Hashimoto's related with eye problems. Unfortunately the only antibodies test results I have are those I put on this post. 
Medi checks blood results
What to do now? unexpected TSH results
Medichecks thyroid results
independant blood test are back
How can I persuade the consultant that I need treatment for my Hashimotos?
