Hi everyone, I'm a 47 year old male, father of 5 lovely children. Ive been active fit & healthy all my life. I was diagnosed with an underactive thyroid around 20 years ago with only mild symptoms of lethargy and slight weight gain. Turned out I needed 250mg of levothyroxine every day. In April my gp had a brainstorm and stopped a repeat prescription because I missed a blood test. This turned my life upside down. I've had serious anxiety leading to seriously powerful panic attacks, no appetite, no energy, I haven't been yo work for 4 weeks. Can't think, can't drive, can't work. Gp genius put me back on 200mg a day after an 8 week hiatus. The sudden shock of returning to such a big dose nearly killed me. Now ive been on 125mg with a review every 4 weeks gradually increasing it when necessary. But Ive bern referred to an endocrinologist who is an expert on human hormones. If your dose is 100mg ir above, you must insist your refers you ASAP as it will save you a mountain of grief because they will domore thorough testing of your blood . Good luck to everyone as its a very hard problem yo solve.