Time of day to take B12?: Hi So I had a private... - Thyroid UK

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Time of day to take B12?

Vicky567 profile image
26 Replies

Hi So I had a private GP appointment yesterday whereby I'm not underactive, but my B12 is low. He told me to start 1000ug. Problem I've got is I drink caffeine in the mornings.....whether that's black coffee or coca cola as I Nedd to wake up so badly as I'm also going through a withdrawal from my antidepressant.

I googled food and drink you shouldn't have if taking B12and it said caffeine.

Now I've only taken thus since yesterday and there has been around 3 hours yesterday from my last mouth full to taking the b12.

Today I left it 5 hours as I'm scared it will affect t absorption.

I Contacted the Dr who saw me who replied in an email that the beauty of taking this at the dose I'm on...means it won't affect absorption..

I've been careful with eating times too....leaving 3 hours after eating to take it, then I'm leaving 1 hour 40 until evening meal.

Can you tell me if me taking it around 2-3pm is OK? Cos I saw on Google best time to take is in the morning but I need to take caffeine first thing at 6.15. Please advise x

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SlowDragon profile image
SlowDragonAmbassador

Best B12 supplements are absorbed in your mouth, not gut

Recommend to take B vitamins in morning after breakfast

how low was your B12

What was folate level

Highly effective B12 drops

natureprovides.com/products...

Or

B12 sublingual lozenges

uk.iherb.com/pr/jarrow-form...

cytoplan.co.uk/shop-by-prod...

In-depth article on different forms of B12

perniciousanemia.org/b12/fo...

B12 range in U.K. is too wide

Interesting that in this research B12 below 400 is considered inadequate

healthunlocked.com/thyroidu...

perniciousanemia.org/b12/le...

And why aiming to keep B12 over 500 recommended

perniciousanemia.org/b12/le...

Great reply by @humanbean on B12 here

healthunlocked.com/thyroidu...

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a separate B12 supplement

A week later add a separate vitamin B Complex 

Then once your serum B12 is over 500 (or Active B12 level has reached 70), you may be able to reduce then stop the B12 and just carry on with the B Complex.

If Vegetarian or vegan likely to need ongoing separate B12 few times a week

B complex also best taken after breakfast

Igennus B complex popular option. Nice small tablets. Most people only find they need one per day. But a few people find it’s not high enough dose and may need 2 per day and/or may need separate methyl folate couple times a week

Post discussing different B complex

healthunlocked.com/thyroidu...

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule) Thorne can be difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 5-6 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg) and continue separate B12 if last test result serum B12 was below 500 or active B12 (private test) under 70

Vicky567 profile image
Vicky567 in reply toSlowDragon

Hi slow dragon..so I took my vitamin bloods with me....the ones I put on here.He said I'm low in folate and B12. B12 was 212 folate 4 9.

Other question I have is today I've had terrible fatigue.....now I'm going through a withdrawal from antidepressant and I have had some fatigue but nothing to today's scale.

Any chance this 1000ug could be too high for me,? I know I have to see how I am tomorrow but today's been awful.

What do you think?

Vicky567 profile image
Vicky567 in reply toSlowDragon

I've also bought those drops ...but I'm not sure which to take? I didn't tell the Dr I had the drops also. I just took along all my different B12 tablets and he said the 1000ug. So you say after breakfast.....what about my caffeine that I drink from 6.15? I have to have it otherwise I'm no good . Most days it picks me up. But it says caffeine doesn't help absorb the B12 .....so should I leave taking it for a couple hrs after the caffeine??

SlowDragon profile image
SlowDragonAmbassador in reply toVicky567

Caffeine won’t have any effect because you are absorbing B12 in your mouth

Nature Provides B12 drops

13 drops = 3000

natureprovides.com/products...?

Suggest initially you start with 5-6 drops and increase slowly up to 13 per day

Add separate vitamin B complex after week or so

Vicky567 profile image
Vicky567 in reply toSlowDragon

Yes you know I thought that....I read the box it said 13 drops....I thought maybe reduce the drops....it said it works quicker too by getting in the blood stream quicker than tablets

Vicky567 profile image
Vicky567 in reply toSlowDragon

Have u used thsee drops? I won't get a reaction will I?

SlowDragon profile image
SlowDragonAmbassador in reply toVicky567

Yes lots of members use them

Start very slowly if you want…..just 1-2 drops first day

Then increase slowly over next week or so

Vicky567 profile image
Vicky567 in reply toSlowDragon

God I'm just so scared I don't know why . I've got alot if anxiety caused by my withdrawal today has really threw me. Ne er been so tired.

So drops you think?

So how much mcg is in 2 drops?

Vicky567 profile image
Vicky567 in reply toSlowDragon

So should I take both 2 drops same time or?

SlowDragon profile image
SlowDragonAmbassador in reply toVicky567

Just take one drop if your worried

Vicky567 profile image
Vicky567 in reply toSlowDragon

I know it sounds silly but yes I am....felt ill today ....I don't want any reaction to it...but one drop should be OK right?

SlowDragon profile image
SlowDragonAmbassador in reply toVicky567

Just try it one morning after breakfast when you feel up to doing so

Vicky567 profile image
Vicky567 in reply toSlowDragon

Ok thank you xx

helvella profile image
helvellaAdministrator in reply toSlowDragon

That company has lost me by this claim:

Why no preservatives?

Protecting the quality and potency of our products is crucial - and we do this without adding any nasty preservatives.

Instead, we use Miron® violet glass which protects your supplements from harmful rays of light while allowing beneficial visible violet, non-visible UVA, and far-Infrared light to enter.

Preservatives are used to prevent biological contamination - bacterial, viral, fungal.

They are not used to prevent the substance being affected by light.

The company appears to be deliberately conflating two entirely different things: preservative use and degradation due to light.

Unless you positively choose to place the bottle somewhere that there is UVA and far-infrared light, the fact that the glass allows transmission does not seem relevant.

Indeed, you can readily find other sources which say the methyl- and adenosyl- are directly affected by UVA exposure.

Obsdian profile image
Obsdian in reply toSlowDragon

What do you mean absorbed in your mouth? Have I been taking mine incorrectly swallowing it?

Vicky567 profile image
Vicky567 in reply toObsdian

To be honest I was confused....but im brand new to all this.

SlowDragon profile image
SlowDragonAmbassador in reply toObsdian

Just let it swirl around in your mouth under your tongue

Obsdian profile image
Obsdian in reply toSlowDragon

Oh! I have been swallowing it all this time.

Vicky567 profile image
Vicky567 in reply toSlowDragon

I'm thinking of skipping a day tomorrow to get my system clean with lots of water then Friday start drop....what you think?

Vicky567 profile image
Vicky567 in reply toSlowDragon

Do you not swallow the drops then??

SlowDragon profile image
SlowDragonAmbassador in reply toVicky567

No they are tiny…just let them swirl around your mouth, especially under your tongue

SlowDragon profile image
SlowDragonAmbassador

Serum folate- 4.9 (3.00- 20.50ug/L

Vitamin B12 - 224 (200.00- 900.00ng/L

Yes these are very low

Very common to feel more tired when first starting on vitamin supplement

Which B12 are you taking

Also iron level is low

Look at increasing iron rich foods in you diet

Serum ferritin - 138 (30.00- 250.00ug/L

Serum iron level - 17 (9.00- 30.00umol/L

Serum transferritin- 3.44 (1.80- 3.82g/L

Transferritin saturation index - 19 (15.00- 50.00%

Vicky567 profile image
Vicky567 in reply toSlowDragon

The brand Solgar 1000ug b12...then he said add the folate 400ug in a month time He also said my iron was fine when. I asked?

Vicky567 profile image
Vicky567 in reply toVicky567

If you were me would you take the drops or the solgar tablets?

SlowDragon profile image
SlowDragonAmbassador in reply toVicky567

Drops

SlowDragon profile image
SlowDragonAmbassador in reply toVicky567

Iron  17  (9 - 30) 

Iron 38.1% through range

Transferrin saturation  19  (15 - 50) 

Transferrin 11.4%

Transferrin saturation  3.44  (1.8 - 3.82) 

Serum Transferrin 81.2% through range

lifeblood.com.au/health-pro...

Elevated transferrin and low transferrin saturation are suggestive of iron deficiency even in the presence of a normal or elevated ferritin.

A transferrin saturation of < 20% is useful to define low iron availability in both absolute and functional iron deficiency.

Look at eating more red meat, liver once a week etc etc

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