Hi - not used to posting yet! My daughter at 25 has been suffering from extreme symptoms and more for over 9 months- pain and pins and needles in legs, hands, headaches everyday, exhaustion and weight gain. Had daily diarrhoea for 9 months or more and pain spleen area. Rheumatoid factor of 40 - should be 10? B12 on low side but Gp said not low enough for injection ! Rheumatologist this week said why no injection? She's had head and spine MRI - all clear thankfully And now further bloods and MRI of hips ordered and referral to gastrologist awaiting. She's pushed herself to go on charity trek up Machu Pichu last September and symptoms heightened sice then. She still pushes herself to work everyday somehow but has no other life . Now on NAX and D3 and B12 sublingually but desperate to help her feel better! I'm hypothyroid for 30+ years and always told to diet etc and some improvement now on T3 only. Seen Dr BDP 6 weeks ago who said very poor adrenals but no real change maybe due to diarrhoea ?? Help??