My son has been showing some symptoms of b12 deficiency lately. I realised that his b12 was low but in range when last tested about a year ago so it is quite possible that it has decreased further. He has been on folic acid for a while as folates were low, he also still has a low vit D although he has been supplementing for some months. I have now discovered that folic acid masks macro blood cells indicating pernicious anaemia and we would like to change to methylfolate. My question is, does methyfolate also mask these increases in blood cell size too? I know if we supplement with b12 now it will affect a test for pernicious anaemia, but he is feeling poorly and I don't know when another blood test will happen as we have to wait a while in order to see the same supportive doctor.
I would be grateful for any comments on latest blood results from a full blood count
red blood cell count 4.85 (4,50 - 5.50)
haemaglobin estimation 151g/l (130 - 170)
haematocrit 0.41L/L (0.40 -0.52)
mean corpuscular volume (MCV) 85.2Fl (83.0 - 100.0)
mean corpuscular haemoglobin (MCH) 31.1pg (27.0 - 32.0)
! mean corpusc Hb conc. (MCHC) 366 g/l (315 - 345)
He is on T4 alternatively daily 75 and 100mg. He is slightly overdosed at present.
TSH 0.09mIU/L (0.27 - 4.20)
FT4 19.5pmol/L (12.0 - 22.0)
FT3 6.8pmol/L (3.9 - 6.7)