Results (or some) have come back - any advice?

Hi Sitrog, you must be feeling pretty awful?

Whilst your TSH is in the lab range, your antibodies, T4 and T3 are not. I'm not hypo but looks to me like you need an increase in Thyroxine.

Your Active B12 result shows that you are B12 deficient. The lab ranges used by St Thomas' are:

<25 pmol/L - vitamin B12 deficient

25-70 pmol/L - samples are referred for confirmatory MMA analysis

>70 pmol/L - vitamin B12 replete

On your result you need treatment via B12 injections. You say you are on B12, do you mean sublinguals? The BNF / NICE guidelines allow for injections every other day until no further improvement where there are neuro symptoms, then 2 monthly maintenance for life. If no neuro symptoms, you should get a loading dose of 6 injections over 2 weeks, followed by 3 monthly maintenance. These guidelines are shown here:

cks.nice.org.uk/anaemia-b12...

To establish what symptoms you have, look at this link:

b12deficiency.info/signs-an...

Have a read around the website, it's full of useful information and links. There is a link to a Facebook group for Pernicious Anaemia (PA) / B12 deficiency which you could join.

You need to ask your doctor to check for the autoimmune antibodies found in PA, these are anti-intrinsic factor and anti-parietal cells. The fact that you are on Omeprazole could actually be the cause of your B12 deficiency, particularly if you have been on it a long time. It also causes Magnesium deficiency incidentally, you should ask your doctor to test Red Cell Magnesium (not Plasma/Serum Magnesium).

Your iron levels are appalling and you are anaemic on your hospital results. How long have you been on iron tablets and at what strength? Without improving your iron you won't get the full benefit from thyroid meds or B12 injections. Did you have Folate and Vitamin D tested? You must ask for them if not, because they are likely low as well. You should also be tested for Coeliac, Crohns etc, have you seen a Gastro before?

I don't know much about glucose but I'm assuming they might want to run more tests to rule out diabetes.

Hampster

Hi you definitely have an underactive thyroid,and by the looks of it it is caused by hashimotos. But a positive thyroid peroxidase antibodies can sometimes indicate another autoimmune disorder.