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Xtandi
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Stopping Xtandi perhaps temporarily due to dementia
Xtandi
hasn’t produced great PSA decline anyway but did seem to level PSA at 8. Also hubby has recent orchiectomy and Provenge last year so he does have that going for him.
Xtandi
hasn’t produced great PSA decline anyway but did seem to level PSA at 8. Also hubby has recent orchiectomy and Provenge last year so he does have that going for him.
Grumpyswife
in
Advanced Prostate Cancer
6 years ago
Climbing psa but low testosterone
If there is disease progression, they’ll move forward with chemo or a clinical trial (randomized
xtandi
vs
xtandi
plus). In the interim they did a blood panel and his psa is up again to 12. His testosterone, however, is remaining at its lowest point. Can anyone tell me how one affects the other?
If there is disease progression, they’ll move forward with chemo or a clinical trial (randomized
xtandi
vs
xtandi
plus). In the interim they did a blood panel and his psa is up again to 12. His testosterone, however, is remaining at its lowest point. Can anyone tell me how one affects the other?
Stumpgirl
in
Advanced Prostate Cancer
6 years ago
"no way to know if it's working"....Wow. Provenge
I signed off to start the
Xtandi
this evening before bedtime...AND I signed off to start Provenge on Tuesday. ** Pic is my first time every for making Homemade chicken & dumplings. It was better (even) than it looked. I LOVE to cook (and eat).
I signed off to start the
Xtandi
this evening before bedtime...AND I signed off to start Provenge on Tuesday. ** Pic is my first time every for making Homemade chicken & dumplings. It was better (even) than it looked. I LOVE to cook (and eat).
greatjohn
in
Advanced Prostate Cancer
6 years ago
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Xtandi AND Provenge so soon?
**this classified me as Castrate Resistant Advanced Stage 4....NOW I'm starting Provenge AND
Xtandi
. These both sound like BIG GUNS...I'm just wondering if anyone is taking both now? / took both? / took both this early in the journey? How it was? Being in the "fast lane" is a bit scary! --John
**this classified me as Castrate Resistant Advanced Stage 4....NOW I'm starting Provenge AND
Xtandi
. These both sound like BIG GUNS...I'm just wondering if anyone is taking both now? / took both? / took both this early in the journey? How it was? Being in the "fast lane" is a bit scary! --John
greatjohn
in
Advanced Prostate Cancer
6 years ago
Xofigo and Zytiga warning
So my RO recommends
xtandi
and xofigo for bone met recurrence upon scan. See below: http://www.ema.europa.eu/docs/en_GB/document_library/Press_release/2018/03/WC500245412.pdf
So my RO recommends
xtandi
and xofigo for bone met recurrence upon scan. See below: http://www.ema.europa.eu/docs/en_GB/document_library/Press_release/2018/03/WC500245412.pdf
Break60
in
Advanced Prostate Cancer
6 years ago
Any thoughts on turning around cachexia (wasting syndrome)?
Starting with triple hormone deprivation (Lupron-Finasteride-Casodex), prostate radiation therapy in 2008, then in 2014 chemo (taxotere), 2015 cryoablation of prostate tumor mass, 2016/2017 Zytiga followed by
Xtandi
, 2017 Xofigo.
Starting with triple hormone deprivation (Lupron-Finasteride-Casodex), prostate radiation therapy in 2008, then in 2014 chemo (taxotere), 2015 cryoablation of prostate tumor mass, 2016/2017 Zytiga followed by
Xtandi
, 2017 Xofigo.
Jim_S_Boston
in
Advanced Prostate Cancer
6 years ago
"OLD" DRUG WORKS PRETTY GOOD
Zytiga/
Xtandi
/ Xofigo/ Provenge/ Olaparib to mention the most important. With the exception of
Xtandi
I have had them all. As we sequentially go through these wonder drugs we keep an eye to what's next? May 2017 I decided to re-evaluate my situation.
Zytiga/
Xtandi
/ Xofigo/ Provenge/ Olaparib to mention the most important. With the exception of
Xtandi
I have had them all. As we sequentially go through these wonder drugs we keep an eye to what's next? May 2017 I decided to re-evaluate my situation.
Terje
in
Advanced Prostate Cancer
6 years ago
PARP Inhibitors.
Some defects are inherited, but resistance to Zytiga &/or
Xtandi
, etc, increases the probability of defects. Perhaps ~20% of mCRPC cases harbor such defects [1].} -Patrick [1] https://www.ncbi.nlm.nih.gov/pubmed/29555412
Some defects are inherited, but resistance to Zytiga &/or
Xtandi
, etc, increases the probability of defects. Perhaps ~20% of mCRPC cases harbor such defects [1].} -Patrick [1] https://www.ncbi.nlm.nih.gov/pubmed/29555412
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Xtandi
I’ve been on
Xtandi
15 months My PSA is climbing I start chemo Thurs Has anyone continued
Xtandi
on chemo?
I’ve been on
Xtandi
15 months My PSA is climbing I start chemo Thurs Has anyone continued
Xtandi
on chemo?
pinejogave
in
Advanced Prostate Cancer
6 years ago
Zytiga or Xtandi effective again after chemo?
Has anyone had experience with PCa becoming sensitive to Zytiga or
Xtandi
again following chemo failure?
Has anyone had experience with PCa becoming sensitive to Zytiga or
Xtandi
again following chemo failure?
Rmanns
in
Advanced Prostate Cancer
6 years ago
Five years fighting Prostate Cancer
I am currently on Lupron,
Xtandi
, and Pembro. It's been an amazing journey. It's made me focus on what's really important, rid myself of toxic relationships, start quilting, traveled to Japan, came out and found a loving relationship.
I am currently on Lupron,
Xtandi
, and Pembro. It's been an amazing journey. It's made me focus on what's really important, rid myself of toxic relationships, start quilting, traveled to Japan, came out and found a loving relationship.
Dash54
in
Advanced Prostate Cancer
6 years ago
An Update To My Profile And Entering A New Phase In My Journey
I asked about Zytega ot
Xtandi
but was lold that there required special approval on the Australian Pharmaceutical Benefits Scheme as they Chemotherapy. I didn't think they were. I will wait to see how things progress and see my my Medical Oncologist who had advised me previously.
I asked about Zytega ot
Xtandi
but was lold that there required special approval on the Australian Pharmaceutical Benefits Scheme as they Chemotherapy. I didn't think they were. I will wait to see how things progress and see my my Medical Oncologist who had advised me previously.
BrianE
in
Advanced Prostate Cancer
6 years ago
New to this site
22 year surviver now worried Psa 70 and rising on
Xtandi
I think it is time fr chemotherapy. Mestatic in lymph nodes and bone meds think I am getting close to the end will the chemo help
22 year surviver now worried Psa 70 and rising on
Xtandi
I think it is time fr chemotherapy. Mestatic in lymph nodes and bone meds think I am getting close to the end will the chemo help
Ptclassics
in
Advanced Prostate Cancer
6 years ago
Radiation
Started
Xtandi
4 pills a day 2 weeks ago. Cancer outside of prostate based on Aximum scan. Met with radiation oncologist today. Wants to radiate lymphnodes left pelvic wall and abdominal cavity. 5 treatments per area. What can I expect?? Anyone have success??
Started
Xtandi
4 pills a day 2 weeks ago. Cancer outside of prostate based on Aximum scan. Met with radiation oncologist today. Wants to radiate lymphnodes left pelvic wall and abdominal cavity. 5 treatments per area. What can I expect?? Anyone have success??
Hidden
in
Advanced Prostate Cancer
6 years ago
Coke Gouda Cheese and What a Difference a Day Makes
I found coke to be the best drink to counteract the fatigue from
Xtandi
and gouda cheese to block stomach upset from Metformin....plus gouda cheese is a good source of vitamin k2.
I found coke to be the best drink to counteract the fatigue from
Xtandi
and gouda cheese to block stomach upset from Metformin....plus gouda cheese is a good source of vitamin k2.
gusgold
in
Advanced Prostate Cancer
6 years ago
Prompted by the Nalakrats / Tall_Allen Debate.
Within the past year, I watched a panel discussion where Johann de Bono (Royal Marsden), reflecting on two drugs he had been deeply involved with - Zytiga &
Xtandi
- worrying that doctors were ill-prepared to manage the changes that occur in cancer that becomes resistant to those drugs.
Within the past year, I watched a panel discussion where Johann de Bono (Royal Marsden), reflecting on two drugs he had been deeply involved with - Zytiga &
Xtandi
- worrying that doctors were ill-prepared to manage the changes that occur in cancer that becomes resistant to those drugs.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Zenith Epigenetics Study Demonstrates Outstanding Results
In Phase 2, Zenith Epigenetics will be focused on continuing the evaluation of efficacy of ZEN-3694 in combination with enzalutamide (
Xtandi
).
In Phase 2, Zenith Epigenetics will be focused on continuing the evaluation of efficacy of ZEN-3694 in combination with enzalutamide (
Xtandi
).
Maxsayulita
in
Advanced Prostate Cancer
6 years ago
XTANDI
The treatment is
Xtandi
. I've been following this blog and have read that many of you are on this medication. Not many variations in treatment out there.
The treatment is
Xtandi
. I've been following this blog and have read that many of you are on this medication. Not many variations in treatment out there.
Hidden
in
Advanced Prostate Cancer
6 years ago
Well...PSA up...and declared Castrate Resistant Advanced Stage 4....I guess there's not level after this one?
AND at the same time I am starting
Xtandi
. Doctor STILL says I should be fine for my trip on August 15th(for 3 weeks) to Europe.
AND at the same time I am starting
Xtandi
. Doctor STILL says I should be fine for my trip on August 15th(for 3 weeks) to Europe.
greatjohn
in
Advanced Prostate Cancer
6 years ago
Brittle nails (on Zytiga/abiraterone)
My husband recently started on Zytiga (after being on
Xtandi
for almost two years). He's noticed that his nails are really brittle, cracking, peeling, ridging. I read about using Aquaphor on them, which we're trying.
My husband recently started on Zytiga (after being on
Xtandi
for almost two years). He's noticed that his nails are really brittle, cracking, peeling, ridging. I read about using Aquaphor on them, which we're trying.
Caring7
in
Advanced Prostate Cancer
6 years ago
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