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Xtandi
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Update on my dad. Need help, hope. Docetaxel over 80?
He has been on zytiga,
xtandi
, still doing zometa and is currently in 3rd treatment of xofigo. He is slowing and weakening a lot. Pain is increasing mainly in hip. If you could see him, though, you'd never guess he's 83! His psa went from 31 in 1/20 to 120 in 2/20.
He has been on zytiga,
xtandi
, still doing zometa and is currently in 3rd treatment of xofigo. He is slowing and weakening a lot. Pain is increasing mainly in hip. If you could see him, though, you'd never guess he's 83! His psa went from 31 in 1/20 to 120 in 2/20.
missh2
in
Advanced Prostate Cancer
4 years ago
The Waiting Game/Post 5 weeks of Radiation for Oligomatastic (3 spots) Prostate cancer after 4 years+ of Stage 4. During "Quarantine"
Today was bloodwork and
Xtandi
and Xgeva...first ones after the radiation. Two days from now (Thursday) I have my Zoom visit with the oncologist. The last couple of weeks of radiation brought quite a bit of stomach and intestinal discomfort....nausea, diarrhea, pain and fatigue.
Today was bloodwork and
Xtandi
and Xgeva...first ones after the radiation. Two days from now (Thursday) I have my Zoom visit with the oncologist. The last couple of weeks of radiation brought quite a bit of stomach and intestinal discomfort....nausea, diarrhea, pain and fatigue.
greatjohn
in
Advanced Prostate Cancer
4 years ago
A small rise in PSA What do you think of my plan
I was tested for ARV-7 and I have no positive activity and would like to go on
Xtandi
next or chemo. Am I not aggressive enough? Just a note, I could only tolerate 500 mg of Zytiga for a 2 yr period which make me think
Xtandi
may work better.
I was tested for ARV-7 and I have no positive activity and would like to go on
Xtandi
next or chemo. Am I not aggressive enough? Just a note, I could only tolerate 500 mg of Zytiga for a 2 yr period which make me think
Xtandi
may work better.
ctflatlander
in
Advanced Prostate Cancer
4 years ago
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Enzalutamide-Resistant PCa & 5-LOX Inhibition.
Seems that Ghosh is still looking at 5-LOX - this time in the context of
Xtandi
resistance: "... even after initial good response, enzalutamide-resistant prostate cancer (ERPC) develops which eventually leads to widespread metastasis.
Seems that Ghosh is still looking at 5-LOX - this time in the context of
Xtandi
resistance: "... even after initial good response, enzalutamide-resistant prostate cancer (ERPC) develops which eventually leads to widespread metastasis.
pjoshea13
in
Advanced Prostate Cancer
4 years ago
advice on weight loss
Just completed 6th treatment (6mnths) of Oxfigo 15 hits of radiation to for painful mets and on
Xtandi
Have lost 45 lbs and the smell and taste of food taste terrible and makes me sick. Is there any members that have dealt with this your suggestion will be appreciated.
Just completed 6th treatment (6mnths) of Oxfigo 15 hits of radiation to for painful mets and on
Xtandi
Have lost 45 lbs and the smell and taste of food taste terrible and makes me sick. Is there any members that have dealt with this your suggestion will be appreciated.
Racer26
in
Advanced Prostate Cancer
4 years ago
Alternative therapies I've had success with, (new here)
The rib lesion continued to live on, in spite of my high-lycopene diet and heat, and my psa got up into the 30's after four years, and I had a fourth hormone therapy just recently (Lupron with
Xtandi
).
The rib lesion continued to live on, in spite of my high-lycopene diet and heat, and my psa got up into the 30's after four years, and I had a fourth hormone therapy just recently (Lupron with
Xtandi
).
NecessarilySo
in
Advanced Prostate Cancer
4 years ago
When do Xtandi side effects show up?
I started
Xtandi
about 10 days ago. So far so good. I am not noticing any significant side effects as of yet... maybe a little more tired in the afternoons, maybe a slightly different pattern to my hot flashes (still on Lupron.)
I started
Xtandi
about 10 days ago. So far so good. I am not noticing any significant side effects as of yet... maybe a little more tired in the afternoons, maybe a slightly different pattern to my hot flashes (still on Lupron.)
Tak-Druk
in
Advanced Prostate Cancer
4 years ago
Take a break?
Solid
Xtandi
and Lupron for over three years now. Undetectable PSA and clean scans every three months. I think they call it progression free survival. However, I feel like shit.
Solid
Xtandi
and Lupron for over three years now. Undetectable PSA and clean scans every three months. I think they call it progression free survival. However, I feel like shit.
Survivor1965
in
Advanced Prostate Cancer
4 years ago
I realize its hopefully a marathon but when should you sprint.
Several weeks ago after zytiga failed some months back it appears that
xtandi
is the next to fail. My PSA is increasing, from 0.08 to 0.4 and now, three weeks later who knows, my next m.o appt is April 17th, labs and lupron and zometa, at the same time.
Several weeks ago after zytiga failed some months back it appears that
xtandi
is the next to fail. My PSA is increasing, from 0.08 to 0.4 and now, three weeks later who knows, my next m.o appt is April 17th, labs and lupron and zometa, at the same time.
Costarica1961
in
Advanced Prostate Cancer
4 years ago
Xtandi and significant back pain
Hello, Looking for feedback from others who have experienced increased back pain while taking
Xtandi
. My dad recently finished BAT at Hopkins and Dr Antonarakis recommended trying
Xtandi
again which did not work very long the first time he was on it.
Hello, Looking for feedback from others who have experienced increased back pain while taking
Xtandi
. My dad recently finished BAT at Hopkins and Dr Antonarakis recommended trying
Xtandi
again which did not work very long the first time he was on it.
Amandaslp78
in
Advanced Prostate Cancer
4 years ago
Borders and Chemotherapy
Been on Erleada, Zolodex,
Xtandi
, Casodex, and Zytiga recently. All failed eventually. Doctor said Docetaxal is all that is left in the bag. I started last week. Now the problem. My wife is Canadian, I am a USA citizen. We had planned to move to Canada soon.
Been on Erleada, Zolodex,
Xtandi
, Casodex, and Zytiga recently. All failed eventually. Doctor said Docetaxal is all that is left in the bag. I started last week. Now the problem. My wife is Canadian, I am a USA citizen. We had planned to move to Canada soon.
dpowellnt
in
Advanced Prostate Cancer
4 years ago
Anyone taking only 1-40 mg. of Xdandi ?
and then take a vacation from
Xtandi
again.
and then take a vacation from
Xtandi
again.
IBstan
in
Advanced Prostate Cancer
4 years ago
Comparing the Clinical Efficacy and Safety of Abiraterone and Enzalutamide in Metastatic CRPC.
New meta-analysis below [1], comparing Abiraterone [Zytiga] and Enzalutamide [
Xtandi
]. "Fourteen cohort studies involving 3469 participants were included." PSA "response was higher for patients receiving enzalutamide than abiraterone (790 patients, odds ratio (OR) 0.47 ..."
New meta-analysis below [1], comparing Abiraterone [Zytiga] and Enzalutamide [
Xtandi
]. "Fourteen cohort studies involving 3469 participants were included." PSA "response was higher for patients receiving enzalutamide than abiraterone (790 patients, odds ratio (OR) 0.47 ..."
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Docetaxel forever?
Chemo Doc says stop
Xtandi
- its not working - (note it was on the Rx list I provided during intake.) My memory is many on this site have continued with the oral along with infusion chemo - correct? He also said that I would be on Docetaxel for years, not months.
Chemo Doc says stop
Xtandi
- its not working - (note it was on the Rx list I provided during intake.) My memory is many on this site have continued with the oral along with infusion chemo - correct? He also said that I would be on Docetaxel for years, not months.
Shepard
in
Advanced Prostate Cancer
4 years ago
Zytiga failed now xtandi. PSA rise after only a few short months from 1.5 to 0.08 now 0.4. Moving on up
I just got the call from my oncologist about a hour ago, she said I'm sorry to inform you your PSA has risen to 0.4 from 0.08 6 weeks ago while currently on
xtandi
, after zytiga has failed.
I just got the call from my oncologist about a hour ago, she said I'm sorry to inform you your PSA has risen to 0.4 from 0.08 6 weeks ago while currently on
xtandi
, after zytiga has failed.
Costarica1961
in
Advanced Prostate Cancer
4 years ago
Who has been on Xofigo? What were side effects and outcome?
I'm currently taking
Xtandi
and I've had an Orchiectomy so no other drugs. When my PSA reached 123 I went on
Xtandi
which knocked it down to 6 but then 3 mos later it was 12 then 22 and now is 25. I should also mention I'm BRCA2.
I'm currently taking
Xtandi
and I've had an Orchiectomy so no other drugs. When my PSA reached 123 I went on
Xtandi
which knocked it down to 6 but then 3 mos later it was 12 then 22 and now is 25. I should also mention I'm BRCA2.
sjpoli46
in
Advanced Prostate Cancer
4 years ago
In these uncertain times I know, I am not the lone ranger. But ?
I have been on
xtandi
for several months, PSA is creeping up from 0.08 to 0.4 as of 3 weeks ago. Zytiga previously failed after 16 mos, rad prostectomy 2016 and radiation 37 sessions. Currently on zometa infusions every 3 months and lupron on same day. Next round April 13th.
I have been on
xtandi
for several months, PSA is creeping up from 0.08 to 0.4 as of 3 weeks ago. Zytiga previously failed after 16 mos, rad prostectomy 2016 and radiation 37 sessions. Currently on zometa infusions every 3 months and lupron on same day. Next round April 13th.
Costarica1961
in
Advanced Prostate Cancer
4 years ago
Poems and Prayers and Promises. Radiation to two lymph nodes in abdomen and to a bone met on left Pelvic bone.... 18 session done out of 25.
A bit MORE fatigue and weakness than with just Lupron and Xgeva and
Xtandi
~~BUT, luckily NO BLOOD in my urine yet or any major G.I. issues(but I really have to watch eating any fiber or fried things).... AND this Coronavirus is making every day going to the hospital another adventure.
A bit MORE fatigue and weakness than with just Lupron and Xgeva and
Xtandi
~~BUT, luckily NO BLOOD in my urine yet or any major G.I. issues(but I really have to watch eating any fiber or fried things).... AND this Coronavirus is making every day going to the hospital another adventure.
greatjohn
in
Advanced Prostate Cancer
4 years ago
Free Xtandi about 80 days of pills
A friend of mine who also has aPC has been taken off of
Xtandi
. His wife wishes to do something positive with the remaining pills. She will send them to someone who is having a difficult time paying for
Xtandi
. I told her I could find some one on Healthunlocked who could use them.
A friend of mine who also has aPC has been taken off of
Xtandi
. His wife wishes to do something positive with the remaining pills. She will send them to someone who is having a difficult time paying for
Xtandi
. I told her I could find some one on Healthunlocked who could use them.
garyg0616
in
Advanced Prostate Cancer
4 years ago
Falling platelets
Gleason 9, stage 4 in 2011 Seeding, radiation, lupron, patch, trelstar, exteva,
xtandi
, more radiation, still on
xtandi
but over last 6 months PSA has been rapidly increasing, then provenge treatment but PSA doubled to 247.
Gleason 9, stage 4 in 2011 Seeding, radiation, lupron, patch, trelstar, exteva,
xtandi
, more radiation, still on
xtandi
but over last 6 months PSA has been rapidly increasing, then provenge treatment but PSA doubled to 247.
Baddawg
in
Advanced Prostate Cancer
4 years ago
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