Ursodiol and Synthroid: Hello PBCers, Hope... - PBC Foundation

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Ursodiol and Synthroid

Liverette profile image
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Hello PBCers,

Hope everyone is doing relatively well. I’ve been diagnosed with PBC years ago but started taking Urso few months ago. My liver enzymes and ALP are normal, however my TSH (thyroid) level has been going up drastically after Urso and my Synthroid dosage is being altered accordingly.

Has anyone experienced TSH change after being in Urso?

Thank you for reading my post.

Taline from Los Angeles

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Liverette
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gwillistexas profile image
gwillistexas

good morning. I do not take URSO but took ocaliva 7 years and it was a struggle to keep my tsh in balance. One extreme to another. I am now on Livdelzi and the pharmacist explained how sensitive thyroid drugs are. So I feel I will face the same problems now. I have no thyroid gland which I feel makes it even more important to keep the levels in the normal range.

Liverette profile image
Liverette in reply togwillistexas

Thank you so much for your reply. I’m suspecting that’s what’s happening with my TSH level jumping up from the new meds Urso. Will have a conversation with my Pharmacist about that. All the best to you!

gwillistexas profile image
gwillistexas in reply toLiverette

Thank you. You as well.

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