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Anti-Androgen Abiraterone Acetate Improves the Therapeutic Efficacy of Statins on Castration-Resistant Prostate Cancer Cells.
New cell study [1] below. I have used Simvastatin for many years to try to prevent the production of cholesterol in PCa cells, & to otherwise limit access to circulating cholesterol. There appears to be synergy between statins & Zytiga (Abiraterone): "We determined that androgen biosynthesis inhibitors
New cell study [1] below. I have used Simvastatin for many years to try to prevent the production of cholesterol in PCa cells, & to otherwise limit access to circulating cholesterol. There appears to be synergy between statins & Zytiga (Abiraterone): "We determined that androgen biosynthesis inhibitors
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Patient Requests for Tests and Treatments Impact Physician Management of Hypothyroidism
See, I keep telling you, it really [i]is[/i] ALL [u]YOUR [/u]FAULT!
[u]You [/u]
are a barrier. Not a concerned patient. Certainly not an informed patient. [i]Thyroid. 2019 Aug 22. doi: 10.1089/thy.2019.0383. [Epub ahead of print]
Patient Requests for Tests and Treatments Impact Physician
See, I keep telling you, it really [i]is[/i] ALL [u]YOUR [/u]FAULT!
[u]You [/u]
are a barrier. Not a concerned patient. Certainly not an informed patient. [i]Thyroid. 2019 Aug 22. doi: 10.1089/thy.2019.0383. [Epub ahead of print]
Patient Requests for Tests and Treatments Impact Physician
helvella
Thyroid UK
in
Thyroid UK
5 years ago
My Aortic Valve Replacement : The lead up to my operation and my decision on the type of valve (I chose the Edwards Inspiris Resilia).
I'm pretty new here and this is only my second post and it’s a long one , so please bear with me. I've done a couple more now which follow on from this, so I hope you find them helpful. I had my op in mid-June in Blackpool Victoria Hospital (BVH). What I have put below covers things up until my actual
I'm pretty new here and this is only my second post and it’s a long one , so please bear with me. I've done a couple more now which follow on from this, so I hope you find them helpful. I had my op in mid-June in Blackpool Victoria Hospital (BVH). What I have put below covers things up until my actual
Robinangel
in
British Heart Foundation
5 years ago
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Statins avoided .. for now
I had been advised to go on statins despite no other risks than high cholesterol Cholesterol reading Dec 18 Tot ... 8.2 HDL ..2.26 LDL ..5.52 Therefore ratio was 3.62 Atovastatin recommended but to go back April for re test Started Benecol first week Jan & together with switching to rapeseed oil(
I had been advised to go on statins despite no other risks than high cholesterol Cholesterol reading Dec 18 Tot ... 8.2 HDL ..2.26 LDL ..5.52 Therefore ratio was 3.62 Atovastatin recommended but to go back April for re test Started Benecol first week Jan & together with switching to rapeseed oil(
JB1959
in
British Heart Foundation
5 years ago
For those on statins: adding dipyridamole might be a good idea
the drug dipyridamole can be used to block statin-induced SREBP activation and augment apoptosis in statin-insensitive PCa cells. In this study fluvastatin was used, maybe not the best option against PCA. Dipyridamole can be taken instead/with aspirin, and there is a version with aspirin in it (Aggrenox
the drug dipyridamole can be used to block statin-induced SREBP activation and augment apoptosis in statin-insensitive PCa cells. In this study fluvastatin was used, maybe not the best option against PCA. Dipyridamole can be taken instead/with aspirin, and there is a version with aspirin in it (Aggrenox
Hidden
in
Advanced Prostate Cancer
5 years ago
Alcohol and meds
I’m on statins, aspirin , bisprolol and ramipril. Interested on peoples experience it’s alcohol. I drink rarelyvin the week but at weekends share a bottle of wine each night.
I’m on statins, aspirin , bisprolol and ramipril. Interested on peoples experience it’s alcohol. I drink rarelyvin the week but at weekends share a bottle of wine each night.
Tess4
in
Arrhythmia Alliance
5 years ago
New to site - diagnosed hypothyroidism with high cholesterol
Hello all, I am 62 year old woman and was diagnosed some years ago with hypothyroidism and have taken Levothyroxine at 50 to 100 gms (varying according to annual testing) with no particular noticeable problems. I have, for a long time, had higher than normal cholesterol levels but dr has always said
Hello all, I am 62 year old woman and was diagnosed some years ago with hypothyroidism and have taken Levothyroxine at 50 to 100 gms (varying according to annual testing) with no particular noticeable problems. I have, for a long time, had higher than normal cholesterol levels but dr has always said
JackyGT
in
Thyroid UK
5 years ago
Big Pharma
The term “Big Pharma” crops up regularly. It is very much a conspiracy theory much like “The moon landing was filmed in the Nevada desert” or “Prince Philip planned the death of Princess Diana”. For some reason many believe that pharmaceutical companies in league with the medical profession operate in
The term “Big Pharma” crops up regularly. It is very much a conspiracy theory much like “The moon landing was filmed in the Nevada desert” or “Prince Philip planned the death of Princess Diana”. For some reason many believe that pharmaceutical companies in league with the medical profession operate in
MichaelJH
Heart Star
in
British Heart Foundation
5 years ago
Do statins work or not?
Recent very interesting report by a reputable hospital: https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/113691-prostate-cancer-development-is-not-affected-by-statin-use-in-patients-with-elevated-psa-levels.html
Recent very interesting report by a reputable hospital: https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/113691-prostate-cancer-development-is-not-affected-by-statin-use-in-patients-with-elevated-psa-levels.html
kryciakrycia
in
Advanced Prostate Cancer
5 years ago
What is causing my itchy throat and mouth?
I am now in my fouth week of having an irritated mouth and throat, I am so frustrated and tired, I dont know what to do. It started off with having an itchy back of mouth which got worse over a week, it got to the point where it was keeping me awake so went to the doctors and the nurse thought it was
I am now in my fouth week of having an irritated mouth and throat, I am so frustrated and tired, I dont know what to do. It started off with having an itchy back of mouth which got worse over a week, it got to the point where it was keeping me awake so went to the doctors and the nurse thought it was
cloverfiat
in
Oesophageal & Gastric Cancer
5 years ago
Simvastatin-induced erythromelalgia: less is more.
A[i]cta Clin Belg. 2019 Jul 10:1-2. doi: 10.1080/17843286.2019.1640929. [Epub ahead of print]
Simvastatin-induced erythromelalgia: less is more.
Vanwonterghem Y1, Shadid S1. Author information 1 a University Hospital Ghent , Department of Endocrinology , Belgium. Abstract We describe a case
A[i]cta Clin Belg. 2019 Jul 10:1-2. doi: 10.1080/17843286.2019.1640929. [Epub ahead of print]
Simvastatin-induced erythromelalgia: less is more.
Vanwonterghem Y1, Shadid S1. Author information 1 a University Hospital Ghent , Department of Endocrinology , Belgium. Abstract We describe a case
helvella
in
The Erythromelalgia Association
5 years ago
Simvastatin-induced erythromelalgia: less is more
This forum, Thyroid UK, is particularly aware of statins and their contra-indications. Furthermore, the whole cholesterol orthodoxy is questioned regularly. This case report is (rightly) explicitly critical of the handling of the woman and her diagnosis of erythromelalgia - rather, failure to diagnose
This forum, Thyroid UK, is particularly aware of statins and their contra-indications. Furthermore, the whole cholesterol orthodoxy is questioned regularly. This case report is (rightly) explicitly critical of the handling of the woman and her diagnosis of erythromelalgia - rather, failure to diagnose
helvella
Thyroid UK
in
Thyroid UK
5 years ago
Recent "research"
I read about a recent study that tries to blame vitamins for the presence of CVD, yes it is another observational study. It does not look at what conventional medicines people are on, and in my opinion is utter tosh. People who take vitamins are normally people who are conscious of their general state
I read about a recent study that tries to blame vitamins for the presence of CVD, yes it is another observational study. It does not look at what conventional medicines people are on, and in my opinion is utter tosh. People who take vitamins are normally people who are conscious of their general state
kasibarndoor
in
Cholesterol Support
5 years ago
Doctors app and request for T3 test
Hi can anyone advise on the following. I had doctors appointment today and asked her for the FT3 test. She said that they only carry out this test if TSH level is normal and because mine is raised at the moment [9.2] the correct treatment is levothyroxine only!! I Also as my cholesterol is 19.4 with
Hi can anyone advise on the following. I had doctors appointment today and asked her for the FT3 test. She said that they only carry out this test if TSH level is normal and because mine is raised at the moment [9.2] the correct treatment is levothyroxine only!! I Also as my cholesterol is 19.4 with
Mazmilly
in
Thyroid UK
5 years ago
Cholesterol
Following blood tests my GP has advised that I start statins. However, I have reviewed my diet and reduced the consumption of a number of fatty foods (50%). So I plan to not start the statins until I have another blood test. How long should I leave it before requesting another blood test?
Following blood tests my GP has advised that I start statins. However, I have reviewed my diet and reduced the consumption of a number of fatty foods (50%). So I plan to not start the statins until I have another blood test. How long should I leave it before requesting another blood test?
RobertCLL
in
CLL Support
5 years ago
Thyroid patent requiring cholesterol readings
I haveunder active thyroid on 50mg Levo 5 days and 75 2 days .had decided to stop statins and just received results but does anyone know if these are good or bad please Serum HDL 1.82 (0.9-3). Serum cholesterol HDL (xauq) 2.6 Non HDL cholesterol 2.98mml. Serum cholesterol Xe2ED 4.8mm now strangely
I haveunder active thyroid on 50mg Levo 5 days and 75 2 days .had decided to stop statins and just received results but does anyone know if these are good or bad please Serum HDL 1.82 (0.9-3). Serum cholesterol HDL (xauq) 2.6 Non HDL cholesterol 2.98mml. Serum cholesterol Xe2ED 4.8mm now strangely
Gettingoldnow
in
Thyroid UK
5 years ago
How to starve cancer by jane Mclelland
In the book Jane lists various cocktails as supplements to conventional treatments.... I would like to know what are the cocktails adapted to Prostate cancer cells.... Beside fat free diet and Green tee she talks of supplements.... Berberine Dipyridamole Metformin aspirin...some type of statins ursolic
In the book Jane lists various cocktails as supplements to conventional treatments.... I would like to know what are the cocktails adapted to Prostate cancer cells.... Beside fat free diet and Green tee she talks of supplements.... Berberine Dipyridamole Metformin aspirin...some type of statins ursolic
Karmaji
in
Advanced Prostate Cancer
5 years ago
statins
im just curious on the level of statins people have prescribed. i had ha and one stent and prescribed 20mg of atorvastatin among the other meds but i see similar people yet on up to 80 mg.my cholesterol came down from 7.8 to around 4. why do some need such a large dose or is mine a low dose
im just curious on the level of statins people have prescribed. i had ha and one stent and prescribed 20mg of atorvastatin among the other meds but i see similar people yet on up to 80 mg.my cholesterol came down from 7.8 to around 4. why do some need such a large dose or is mine a low dose
jon2018
in
British Heart Foundation
5 years ago
HEART ATTACK RISK ASSOCIATED WITH ADT...
Anyone have real data re: true risk of heart attack as a result of ADT....All my life I have had high cholesterol....diet makes little difference...refused Statins. My Calcium Score is presently Zero ( or WAS 2 years ago).... Will probably consider a statin as part of pca protocol.... Will be starting
Anyone have real data re: true risk of heart attack as a result of ADT....All my life I have had high cholesterol....diet makes little difference...refused Statins. My Calcium Score is presently Zero ( or WAS 2 years ago).... Will probably consider a statin as part of pca protocol.... Will be starting
Tommyj2
in
Advanced Prostate Cancer
5 years ago
Statins and Nerve Damage (Peripheral Neuropathy): An Overlooked Side Effect!
https://www.peoplespharmacy.com/articles/statins-and-nerve-damage-peripheral-neuropathy-an-overlooked-side-effect/?utm_source=The+People%27s+Pharmacy+Newsletter&utm_campaign=41725b5b18-MC_D_2019-07-09%26subscriber%3D1&utm_medium=email&utm_term=0_7300006d3c-41725b5b18-220959569&goal=0_7300006d3c-41725b5b18
https://www.peoplespharmacy.com/articles/statins-and-nerve-damage-peripheral-neuropathy-an-overlooked-side-effect/?utm_source=The+People%27s+Pharmacy+Newsletter&utm_campaign=41725b5b18-MC_D_2019-07-09%26subscriber%3D1&utm_medium=email&utm_term=0_7300006d3c-41725b5b18-220959569&goal=0_7300006d3c-41725b5b18
Dmactds
in
Lung Conditions Community Forum
5 years ago
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