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Transurethral resection of the prostate (TURP)
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bicalutamide no longer as effective?
After more than two years of bicalutamide monotherapy and repeated PSA<0.1 I just received a 0.6. Before the bicalutamide my PSMA scan showed activity in only the seminal vesicle region. PSA was 2.5 at that time. Lupron had ceased being effective. Bicalutamide had a terrific response. I don’t think PSMA
After more than two years of bicalutamide monotherapy and repeated PSA<0.1 I just received a 0.6. Before the bicalutamide my PSMA scan showed activity in only the seminal vesicle region. PSA was 2.5 at that time. Lupron had ceased being effective. Bicalutamide had a terrific response. I don’t think PSMA
kreg001
in
Advanced Prostate Cancer
8 months ago
Elevated PSA 8 weeks after Robotic Prostatectomy
At the age of 70 my most recent treatment was a Robotic Prostatectomy after which pathology report was Gl 3+4 prostate cancer, pT3a (EPE and bladder neck invasion), N1 (1/15 nodes positive), multiple positive margins.( Prior to that I underwent Cryotherapy for prostate cancer in Mar 2012.) My PSA level
At the age of 70 my most recent treatment was a Robotic Prostatectomy after which pathology report was Gl 3+4 prostate cancer, pT3a (EPE and bladder neck invasion), N1 (1/15 nodes positive), multiple positive margins.( Prior to that I underwent Cryotherapy for prostate cancer in Mar 2012.) My PSA level
OLDSALTY2008
in
Advanced Prostate Cancer
8 months ago
How prostate cancer transforms into aggressive NEPC following treatment with anti-androgen therapy.
This could be a game changer as it could stop PCa from progressing. Science is going to save us. The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant
This could be a game changer as it could stop PCa from progressing. Science is going to save us. The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant
Scout4answers
in
Advanced Prostate Cancer
9 months ago
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Explain my PSMA PET SCAN Please..
PSMA PET/CT from the skull base to midthigh demonstrates: 1. Worsening of skeletal metastases. 2. Multiple sclerotic lesions without activity represent treated metastatic disease. 3. Status post orchiectomy. 4. No abnormal uptake of tracer within the prostatic bed. EXAM: PET CT PSMA CLINICAL
PSMA PET/CT from the skull base to midthigh demonstrates: 1. Worsening of skeletal metastases. 2. Multiple sclerotic lesions without activity represent treated metastatic disease. 3. Status post orchiectomy. 4. No abnormal uptake of tracer within the prostatic bed. EXAM: PET CT PSMA CLINICAL
God_Loves_Me
in
Advanced Prostate Cancer
3 months ago
Next steps after PBRT
Hi all - First and foremost, Happy Holidays. I had my prostate removed 8/22, with subsequent Proton Beam treatment ending 4/23 (after PSA did not drop to undetectable) brought upon after a mild uptake (during a Petscan) in an obturator lymph node. I’m on Orgovyx and Xtandi, with a plan to stay on them
Hi all - First and foremost, Happy Holidays. I had my prostate removed 8/22, with subsequent Proton Beam treatment ending 4/23 (after PSA did not drop to undetectable) brought upon after a mild uptake (during a Petscan) in an obturator lymph node. I’m on Orgovyx and Xtandi, with a plan to stay on them
Vp7174
in
Advanced Prostate Cancer
7 months ago
Moving on to Provenge/Sipuleucel-t
We met with my husband's onc yesterday to discuss the next move since the 3 years of Abiraraterone/prednisone has run its course. His psa numbers are now around 2.0 (up from a low of .04) and psma scan indicates that bone met volume is quite low. A recent lab biopsy didn't reveal much... The good doc
We met with my husband's onc yesterday to discuss the next move since the 3 years of Abiraraterone/prednisone has run its course. His psa numbers are now around 2.0 (up from a low of .04) and psma scan indicates that bone met volume is quite low. A recent lab biopsy didn't reveal much... The good doc
Lavender22
in
Advanced Prostate Cancer
3 months ago
Pancreas problems after RT for prostate
I was diagnosed with prostate cancer two years ago. Received radiotherapy and hormone therapy. My PSA levels have dropped and progress seems OK. I have also had M.E. and fibromyalgia for over 25 years and, as part of that, IBS. Since starting the hormone therapy and radiotherapy I became more and more
I was diagnosed with prostate cancer two years ago. Received radiotherapy and hormone therapy. My PSA levels have dropped and progress seems OK. I have also had M.E. and fibromyalgia for over 25 years and, as part of that, IBS. Since starting the hormone therapy and radiotherapy I became more and more
Nomojo56
in
Pelvic Radiation Disease Association
3 months ago
Wondering if anyone can relate to these symptoms
After an appointment with a dietician I was tested for suspected EPI and my level was very low - 53. I have been prescribed Creon 25000 and taking those for about 4 weeks.I have had M.E/CFS and fibromyalgia for over 25 years and two years ago was diagnosed with prostate cancer. I had radiotherapy and
After an appointment with a dietician I was tested for suspected EPI and my level was very low - 53. I have been prescribed Creon 25000 and taking those for about 4 weeks.I have had M.E/CFS and fibromyalgia for over 25 years and two years ago was diagnosed with prostate cancer. I had radiotherapy and
Nomojo56
in
Chronic Pancreatitis Support
3 months ago
Protocol for FET - Anyone had similar??
Hi everyone! Had egg collection & PGT and we have 1 suitable embryo. Call today with 2 proposed protocols, medicated & natural. We are leaning more towards medicated which entails Prostap, Progynova, Buserelin & Cycolgest. Curious if anyone else has experienced this and what to expect?? TIA ❣️
Hi everyone! Had egg collection & PGT and we have 1 suitable embryo. Call today with 2 proposed protocols, medicated & natural. We are leaning more towards medicated which entails Prostap, Progynova, Buserelin & Cycolgest. Curious if anyone else has experienced this and what to expect?? TIA ❣️
Pinklily2
in
Fertility Network UK
4 months ago
225Ac-PSMA-I&T works well even after Pluvicto in small trial
It's small number of heavily-treated mCRPC patients, but 42% of those who already had Pluvicto had a PSA reduction of ≥50% from 225Ac-PSMA-I&T. Surprisingly, no Grade 3 Xerostomia. Phase III trials will likely follow. https://www.prnewswire.com/news-releases/fusion-pharmaceuticals-announces-presentation-of-interim-data-from-the-phase
It's small number of heavily-treated mCRPC patients, but 42% of those who already had Pluvicto had a PSA reduction of ≥50% from 225Ac-PSMA-I&T. Surprisingly, no Grade 3 Xerostomia. Phase III trials will likely follow. https://www.prnewswire.com/news-releases/fusion-pharmaceuticals-announces-presentation-of-interim-data-from-the-phase
Tall_Allen
in
Advanced Prostate Cancer
3 months ago
Signatera tumor dna test
Has anyone heard of using the Signatera test from Natera to detect the presence of prostate cancer recurrence when PSA is rising but the PSMA PET scan is negative?
Has anyone heard of using the Signatera test from Natera to detect the presence of prostate cancer recurrence when PSA is rising but the PSMA PET scan is negative?
shihtzu124
in
Advanced Prostate Cancer
8 months ago
PSA Dropped after 22 days of Zytiga
On Nov 1, my cancer was diagnosed as castrate resistant. Abiraterone and Prednisone was added to Lupron. On November 3 I had a Lupron shot and started Abiraterone and Prednisone on November 10. Today I had a PSA test. My PSA dropped from 0.8 on November 1 to 0.44 today. I was not expecting such dramatic
On Nov 1, my cancer was diagnosed as castrate resistant. Abiraterone and Prednisone was added to Lupron. On November 3 I had a Lupron shot and started Abiraterone and Prednisone on November 10. Today I had a PSA test. My PSA dropped from 0.8 on November 1 to 0.44 today. I was not expecting such dramatic
dac500
in
Advanced Prostate Cancer
8 months ago
Suddenly Urinary Leakage just walking around, then I have to push / strain to urinate, PSA rising, prostatectomy leakage resolved
Can anyone give me an idea what is going on? No UTI, No Urinary Infections I was tested Suddenly having Urinary Leakage just walking around, then I have to push / strain, to urinate. I had a Radical Prostatectomy in 03/2023 leakage resolved. I didn’t have radiation as much as I was waiting
Can anyone give me an idea what is going on? No UTI, No Urinary Infections I was tested Suddenly having Urinary Leakage just walking around, then I have to push / strain, to urinate. I had a Radical Prostatectomy in 03/2023 leakage resolved. I didn’t have radiation as much as I was waiting
Shorehousejam
in
Advanced Prostate Cancer
3 months ago
What are my options?
My bio is not necessarily up to date. I will update it but her is my most recent history and questions: I was getting Pluvicto treatments. Was supposed to get 6 but foe some reason that is not entirely clear at this point it was decided (i have three oncologist and do not know which one or combination
My bio is not necessarily up to date. I will update it but her is my most recent history and questions: I was getting Pluvicto treatments. Was supposed to get 6 but foe some reason that is not entirely clear at this point it was decided (i have three oncologist and do not know which one or combination
spencoid2
in
Advanced Prostate Cancer
3 months ago
What testosterone test should I get in my final blood test prior to HT starting?
Hi All, I intend on getting my own blood test that will form the baseline for how the future HT is working. When it comes to getting testosterone tests, I note there are a few to select from. Which one should I get from the following list? 1: Testosterone Free/Total + SHBG 2: Testosterone Total
Hi All, I intend on getting my own blood test that will form the baseline for how the future HT is working. When it comes to getting testosterone tests, I note there are a few to select from. Which one should I get from the following list? 1: Testosterone Free/Total + SHBG 2: Testosterone Total
CJ1958
in
Prostate Cancer Network
7 months ago
Just some good news
Just wanted to update you all on this in case anyone is thinking of surgery to fix something non-cancer related. My husband was looking into getting a hip replacement back in 2021 when he was diagnosed with PC. So the hip replacement was put on hold,. But the hip arthritis kept getting worse and he
Just wanted to update you all on this in case anyone is thinking of surgery to fix something non-cancer related. My husband was looking into getting a hip replacement back in 2021 when he was diagnosed with PC. So the hip replacement was put on hold,. But the hip arthritis kept getting worse and he
Bspouse
in
Advanced Prostate Cancer
3 months ago
ADT 's effect on body fat and muscle mass from Life on ADT blog by Richard Wassersug
ADT’s impact on Muscle and Fat October 23, 2023 Standard ADT with either LHRH agonist or antagonist drugs (like Lupron or Firmagon, respectively) cause a loss of lean muscle mass and weight gained as fat. Those are among the most common side effects of ADT. Patients experience this as fatigue for they
ADT’s impact on Muscle and Fat October 23, 2023 Standard ADT with either LHRH agonist or antagonist drugs (like Lupron or Firmagon, respectively) cause a loss of lean muscle mass and weight gained as fat. Those are among the most common side effects of ADT. Patients experience this as fatigue for they
Scout4answers
in
Advanced Prostate Cancer
9 months ago
Remission
In remission since May 2018. All PSA testing from oncologist has ranged from .04 to .05. Why not have my internist take my PSA yearly? Or is going to my oncologist for testing the better way to go?
In remission since May 2018. All PSA testing from oncologist has ranged from .04 to .05. Why not have my internist take my PSA yearly? Or is going to my oncologist for testing the better way to go?
Coupe31
in
Advanced Prostate Cancer
7 months ago
still here
Hi All I like to try and update my journey so you can see that there are some longer term survivors. I am still on 0 PSA with advanced cancer. My journey is on my bio. I was diagnosed at 47 and now I’m 54 with no progression. My primary treatment was Zytiga and it is still working. I take a concoction
Hi All I like to try and update my journey so you can see that there are some longer term survivors. I am still on 0 PSA with advanced cancer. My journey is on my bio. I was diagnosed at 47 and now I’m 54 with no progression. My primary treatment was Zytiga and it is still working. I take a concoction
Apollo123
in
Advanced Prostate Cancer
7 months ago
Pelvic pain on prostap
Hello, i am experiencing very bad pelvic and lower back pain. i am 35 with adenomyosis, i didn't know i had this until i had an MRI. They put me on prostap 3 and i have had none stop pelvic pain and on/off bleeding. I am nearly 9 weeks in to the 3 monthly injection. Please help, is this normal? i haven't
Hello, i am experiencing very bad pelvic and lower back pain. i am 35 with adenomyosis, i didn't know i had this until i had an MRI. They put me on prostap 3 and i have had none stop pelvic pain and on/off bleeding. I am nearly 9 weeks in to the 3 monthly injection. Please help, is this normal? i haven't
SallyK2589
in
Endometriosis UK
4 months ago
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