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Transurethral resection of the prostate (TURP)
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IMRT WITHOUT THE JELL
I'm scheduled for IMRT Radistion without the jell. Doc says the jell may push cancer microscopic cells away from the prostate. He said the cancer is about to protrude through the capsule and microsopic cancer cells could be out of the capsule and did not want to take a chance of putting the jell in and
I'm scheduled for IMRT Radistion without the jell. Doc says the jell may push cancer microscopic cells away from the prostate. He said the cancer is about to protrude through the capsule and microsopic cancer cells could be out of the capsule and did not want to take a chance of putting the jell in and
woppaginny
in
Advanced Prostate Cancer
2 months ago
Cabazitaxel Questions
I have switched from Docetaxel to Cabazitaxel. Should I still take the Grastofil injections?
I have switched from Docetaxel to Cabazitaxel. Should I still take the Grastofil injections?
Islandboy2021
in
Advanced Prostate Cancer
2 months ago
Curious about Prednisone dosage.
Warriors If you do not mind telling me, I am curious about how many of you on Zytiga/Abiraterone take a 5 mg dosage of Prednisone , and how many take some other dosage level. I know most of your also getting Lupron injections and some are taking other medications along with the Zytiga/Abiraterone
Warriors If you do not mind telling me, I am curious about how many of you on Zytiga/Abiraterone take a 5 mg dosage of Prednisone , and how many take some other dosage level. I know most of your also getting Lupron injections and some are taking other medications along with the Zytiga/Abiraterone
85236442968
in
Advanced Prostate Cancer
2 months ago
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Caffeic acid phenethyl ester (CAPE) is an ingredient in bee propolis. See below for invitro and mice evidence for inhibition AR-V7 by CAPE
Human studies needed. Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer Gene Therapy (2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant
Human studies needed. Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer Gene Therapy (2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant
Graham49
in
Advanced Prostate Cancer
2 months ago
Eligard injection site
I’m changing from 3 month Lupron to 6 month Eligard. Lupron has always been injected in my hip and I’m wondering if Eligard can also use the same site. Thanks in advance for your comments.
I’m changing from 3 month Lupron to 6 month Eligard. Lupron has always been injected in my hip and I’m wondering if Eligard can also use the same site. Thanks in advance for your comments.
Lslal
in
Advanced Prostate Cancer
2 months ago
Nubeqa Commercial
Anybody else out there getting the Nubeqa commercial on every commercial break? It's pissing me off. I feel targeted and getting reminded that I have metastatic prostate cancer on every commercial break sucks!! I can't get to the mute button fast enough. If I am targeted by use of my searchs somehow
Anybody else out there getting the Nubeqa commercial on every commercial break? It's pissing me off. I feel targeted and getting reminded that I have metastatic prostate cancer on every commercial break sucks!! I can't get to the mute button fast enough. If I am targeted by use of my searchs somehow
treedown
in
Advanced Prostate Cancer
2 months ago
Using Enzalutamide, Darolutamide, Apalutamide only.
I've seen a number of posters here and there who say they use one of the "mides" listed above with no ADT like Lupron, Eligard, Firmagan, or Orgovyx, etc. If so, did you begin that regimen after being on first level ADT for a while along with the 'mide," or did you start on the "mide" alone at the start
I've seen a number of posters here and there who say they use one of the "mides" listed above with no ADT like Lupron, Eligard, Firmagan, or Orgovyx, etc. If so, did you begin that regimen after being on first level ADT for a while along with the 'mide," or did you start on the "mide" alone at the start
dhccpa
in
Prostate Cancer Network
2 months ago
Dutasteride Black Box Warning Label is Inappropriate.
This plot that I made goes back to the original paper by Thompson et al. (2003), that was the basis for slapping the Black Box Warning Label on Dutasteride prescriptions. https://pubmed.ncbi.nlm.nih.gov/12824459/ There are some important points that should be considered: (1) Thompson only studied
This plot that I made goes back to the original paper by Thompson et al. (2003), that was the basis for slapping the Black Box Warning Label on Dutasteride prescriptions. https://pubmed.ncbi.nlm.nih.gov/12824459/ There are some important points that should be considered: (1) Thompson only studied
janebob99
in
Prostate Cancer Network
2 months ago
Length of Treatment for Orgovyx (Relugolix) versus Lupron and other Longer Acting ADT drugs as Adjuvant to RT or Used for IADT?
I'm curious if anyone has had any discussion with their MO or Radiation Oncologist about having to take a longer course of Orgovyx compared to Lupron or other longer acting ADT drugs because Testosterone comes back so much quicker on Orgovyx? It would seem to me, 6 months of Orgovyx is like the equivalent
I'm curious if anyone has had any discussion with their MO or Radiation Oncologist about having to take a longer course of Orgovyx compared to Lupron or other longer acting ADT drugs because Testosterone comes back so much quicker on Orgovyx? It would seem to me, 6 months of Orgovyx is like the equivalent
jazj
in
Advanced Prostate Cancer
2 months ago
promising delivery technique for cancer drugs
we will attack you in any possible way from every direction you bastard (ok, I talk to my cancer, don’t call me crazy…I would be crazy if I heard him reply!) https://pubs.acs.org/doi/10.1021/acsbiomaterials.3c01540# from your one reference in the paper: Chondroitin sulfate-hybridized zein nanoparticles
we will attack you in any possible way from every direction you bastard (ok, I talk to my cancer, don’t call me crazy…I would be crazy if I heard him reply!) https://pubs.acs.org/doi/10.1021/acsbiomaterials.3c01540# from your one reference in the paper: Chondroitin sulfate-hybridized zein nanoparticles
Maxone73
in
Advanced Prostate Cancer
2 months ago
Maybe an alternative to Nattokinase et al, though not yet
Free link to WSJ article https://www.wsj.com/health/pharma/blood-thinners-prevent-clots-bleeding-abd9fdae?st=ofx7h2a2im27x9c&reflink=desktopwebshare_permalink I will study later, but the chemistry is probably beyond me and, anyway, it is not yet available. Factor XI, it turns out, is crucial for
Free link to WSJ article https://www.wsj.com/health/pharma/blood-thinners-prevent-clots-bleeding-abd9fdae?st=ofx7h2a2im27x9c&reflink=desktopwebshare_permalink I will study later, but the chemistry is probably beyond me and, anyway, it is not yet available. Factor XI, it turns out, is crucial for
cigafred
in
Fight Prostate Cancer
2 months ago
Update: Carbo/Etoposide for Dad’s Liver Mets
My dad has his 6th round of Carbo/Etoposide next week. The last 2 rounds have been very difficult on my dad. We thought he was lucky in the beginning as the side effects were manageable and attributed it to my dad being young and previously very active. It’s definitely true that chemo is cumulative.
My dad has his 6th round of Carbo/Etoposide next week. The last 2 rounds have been very difficult on my dad. We thought he was lucky in the beginning as the side effects were manageable and attributed it to my dad being young and previously very active. It’s definitely true that chemo is cumulative.
antisocialsocialwrkr
in
Advanced Prostate Cancer
9 months ago
Was there ever really a chance for a cure?
When I began the Stampede protocol 1 1/2 yrs ago, it was my understanding that two years of Zytiga/Prednisone and three years of Lupon with radiation to the pelvic area at the 7 mo - 1 yr mark gave a chance for a "cure" under my conditions (3+4 gleason, etc). Now, my non-medical view of things is convincing
When I began the Stampede protocol 1 1/2 yrs ago, it was my understanding that two years of Zytiga/Prednisone and three years of Lupon with radiation to the pelvic area at the 7 mo - 1 yr mark gave a chance for a "cure" under my conditions (3+4 gleason, etc). Now, my non-medical view of things is convincing
duxlubber
in
Advanced Prostate Cancer
2 months ago
Big company buys a clinical research company focused on Actinium 225 (and others) FPI-2265
astra-something buys a Canadian company because they hate Canadians...no, sorry...ok, I will sound like a financial advisor, but here it is: Astra-something has been working on other approaches to develop more targeted cancer treatments, including antibody-drug conjugates and RCs. "The deal has solid
astra-something buys a Canadian company because they hate Canadians...no, sorry...ok, I will sound like a financial advisor, but here it is: Astra-something has been working on other approaches to develop more targeted cancer treatments, including antibody-drug conjugates and RCs. "The deal has solid
Maxone73
in
Advanced Prostate Cancer
2 months ago
Brain Fog or Dimentia?
Hey warriors! So how do you know if you have brain fog or the beginning of dementia? Is it possible to blame ADT and Zytiga? My husband has been on Ellegaard for five years and Zytiga for 2 1/2. Years, he seems to have a lot of memory issues lately, and I fear it’s only getting worse Any thoughts or
Hey warriors! So how do you know if you have brain fog or the beginning of dementia? Is it possible to blame ADT and Zytiga? My husband has been on Ellegaard for five years and Zytiga for 2 1/2. Years, he seems to have a lot of memory issues lately, and I fear it’s only getting worse Any thoughts or
Keeper70
in
Advanced Prostate Cancer
2 months ago
Seeking anyone familiar with aggressive small cell neuroendocrine prostate cancer and/or with lurbinectedin as 2nd line chemotherapy.
A needle biopsy Oct 15, 2023 revealed that at least some of my metastatic prostate cancer in a lymph node had mutated to an aggressive small cell neuroendocrine prostate cancer. (notable for CDK N1B, RB1, Tp53 mutations. MSS, TMB low) I had 4 cycles of carboplatin/etoposide chemotherapy, which ended
A needle biopsy Oct 15, 2023 revealed that at least some of my metastatic prostate cancer in a lymph node had mutated to an aggressive small cell neuroendocrine prostate cancer. (notable for CDK N1B, RB1, Tp53 mutations. MSS, TMB low) I had 4 cycles of carboplatin/etoposide chemotherapy, which ended
silver5
in
Advanced Prostate Cancer
2 months ago
Fatiqued and wiped out feeling
I started lupron injection 5 months ago and starting my second month on nubeqa. I am extremely fatiqued and feel wiped out all the time. No ambition to do anything. Climbing stairs is an efford have to force myself to get out of bed. Cannot sleep very well. When I get up it feels like I have not slept
I started lupron injection 5 months ago and starting my second month on nubeqa. I am extremely fatiqued and feel wiped out all the time. No ambition to do anything. Climbing stairs is an efford have to force myself to get out of bed. Cannot sleep very well. When I get up it feels like I have not slept
woppaginny
in
Advanced Prostate Cancer
2 months ago
NUV-1511 drug-drug conjugate (DDC) to enter the clinical stage: phase 1
"Dosing the first patient with NUV-1511 marks a significant milestone for our proprietary DDC platform, from which we are developing potent oncology-focused chimeric small molecules designed to selectively deliver anti-cancer therapeutics to cancer cells, while mitigating effects on healthy non-target
"Dosing the first patient with NUV-1511 marks a significant milestone for our proprietary DDC platform, from which we are developing potent oncology-focused chimeric small molecules designed to selectively deliver anti-cancer therapeutics to cancer cells, while mitigating effects on healthy non-target
Maxone73
in
Advanced Prostate Cancer
2 months ago
Tri modality conclusion end of ADT nervous
A long journey.. Lutron , bicalutamide .. from start last year in June .. brachytherapy.. in October… 15 booster LiNac in Dec/Jan .. doctor ..in Japan said can stop hormone treatment but he sort of front loaded the ADT before radiation 5 months.My second opinion initially said to embrace adjuvant ADT
A long journey.. Lutron , bicalutamide .. from start last year in June .. brachytherapy.. in October… 15 booster LiNac in Dec/Jan .. doctor ..in Japan said can stop hormone treatment but he sort of front loaded the ADT before radiation 5 months.My second opinion initially said to embrace adjuvant ADT
Yokohama2023
in
Advanced Prostate Cancer
2 months ago
xtandi
Medicare denied coverage of this. My dad needs it badly. Cancer in his spine growing. Starting to affect his ability to walk more and more everyday. We have spine pain management apt tmrw. Meet with radiology on Friday. Hopefully the can help him asap.
Medicare denied coverage of this. My dad needs it badly. Cancer in his spine growing. Starting to affect his ability to walk more and more everyday. We have spine pain management apt tmrw. Meet with radiology on Friday. Hopefully the can help him asap.
Hereformydad2022
in
Advanced Prostate Cancer
2 months ago
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