any similar stories extensive metastatic prostate cancer

[Concerneddaughter123]

hello! I’ve been on here for a few weeks reading everyone’s posts, which have been helpful. My dad recently found out he has extensive Mets throughout his skeleton, although we have been battling this disease for almost 5 years now, things have taken a turn. He has been on ADT since January, and tolerating it well. He is active almost daily. I believe chemo is the next step according to his MO. Gleason 9, original diagnosis in 2019. Does anyone have similar diagnoses with some uplifting stories?

[j-o-h-n]

If you don't get any or just a few responses.... try posting again after the Memorial day weekend. Give my regards to you dear 70 year old Dad.

Good Luck, Good Health and Good Humor.

j-o-h-n

[chips1942]

Hi, Read about and ask your RO about the efficacy of Ra225 for extensive bone Mets. The treatment specifically targets bone metastasis and has few side effects.

[Concerneddaughter123 in reply to chips1942]

Thank you for the reply, have you been on Ra225 before? It seems like many say it’s tolerable like you mentioned.

[chips1942 in reply to Concerneddaughter123]

I managed my uncles PCa care in his 80’s and 90’s. He was treated with Ra225 at about 90 with few if any SEs. Died at 96 of other causes, A very good man!

[Concerneddaughter123 in reply to chips1942]

wow, at 90 he was getting treatment! To live to be 96! Sounds like he had good help from you!

[God_Loves_Me in reply to Concerneddaughter123]

if you are thinking to do Radium225 then also do with provenge. It will give you best results. Proveng do not have severe side effects

[God_Loves_Me]

I read your bio and understand that there is no pain. He is also very active. Understanding PSA doubling time is very important.

Have you thought about docetaxel chemo + ADT + AR, which is called triplet therapy, and the best results?

There are many target therapies, such as immunotherapy and clinical trials.

prostatecancer.news/2022/10...

Quick questions that I did not find in your bio.

How many active mets are from PSMA PET?

What's his last PSA?

Does he have any Germline Mutations or Genomic Mutations?

[Concerneddaughter123 in reply to God_Loves_Me]

thank you for the reply. He has extensive bone Mets… too many to count. His PSA has never been a good indicator of how the disease is, so they don’t follow it anymore, but his last PSA was around 6. No mutations were found.

I’ve read a lot about triplet therapy. I can imagine the side effects could be pretty bad with all three, but it seems to have good results for many.

[God_Loves_Me in reply to Concerneddaughter123]

Just search in the group for triplet therapy and read all the side effects

Target therapy:

Pluvicto

Radium 223

Here are top ADC therapies with minimal side effects

healthunlocked.com/advanced...

Top immunotherapy - Discuss with your dr

healthunlocked.com/advanced...

try to enroll in this clinical trials. Great announcement -

healthunlocked.com/advanced...

[Concerneddaughter123 in reply to God_Loves_Me]

Thank you so much!

[God_Loves_Me]

Great content from Tall_Allen

Pluvicto+Xtandi Delays Progression Better than Xtandi-alone in mCRPC

prostatecancer.news/2024/04...

[Concerneddaughter123 in reply to God_Loves_Me]

Very helpful, thank you.