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Skull met has spread
My appointment with my oncologist yesterday made me aware after reviewing the MRI from last week, that the met that was on my skull is now spread into soft matter in my head. I was set to start a double Chemo treatment yesterday , but it was decided the treatment would do no good, and that quality
My appointment with my oncologist yesterday made me aware after reviewing the MRI from last week, that the met that was on my skull is now spread into soft matter in my head. I was set to start a double Chemo treatment yesterday , but it was decided the treatment would do no good, and that quality
docbulldog
in
Advanced Prostate Cancer
1 month ago
Does ADT work for Gleason 9?
About to start ADT for Gleason 9 (5+4) for locally advanced prostate cancer, followed by IMRT in 1-2 months. (Plan to ask about HDR boost). PSMA Pet negative for spread but MO had another radiologist look at initial prostate MRI suggests extracapsular extension along neurovascular bundle with possible
About to start ADT for Gleason 9 (5+4) for locally advanced prostate cancer, followed by IMRT in 1-2 months. (Plan to ask about HDR boost). PSMA Pet negative for spread but MO had another radiologist look at initial prostate MRI suggests extracapsular extension along neurovascular bundle with possible
Hope49823
in
Advanced Prostate Cancer
4 months ago
Meta analysis of Eastern Cooperative Oncology Group(ECOG) PS predicts OS regardless of category, previous chemotherapy, and mPC population
”Overall, 75 studies, comprising 32,298 patients, were included. Most studies (72/75) included patients with mCRPC. Higher ECOG PS was associated with a significant increase in mortality risk, with the highest estimate observed among patients with mCRPC with an ECOG PS of ≥2 versus <2 (hazard ratio [
”Overall, 75 studies, comprising 32,298 patients, were included. Most studies (72/75) included patients with mCRPC. Higher ECOG PS was associated with a significant increase in mortality risk, with the highest estimate observed among patients with mCRPC with an ECOG PS of ≥2 versus <2 (hazard ratio [
Graham49
in
Advanced Prostate Cancer
1 month ago
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Lutetium at earlier stage, clinical trial is enrolling
The second trial provides men with metastatic prostate cancer access to prostate-specific membrane antigen (PSMA)-targeted therapy prior to chemotherapy. Currently, PSMA-targeted therapy is only available after chemotherapy. However, phase III clinical trials have shown that PSMA-targeted therapies are
The second trial provides men with metastatic prostate cancer access to prostate-specific membrane antigen (PSMA)-targeted therapy prior to chemotherapy. Currently, PSMA-targeted therapy is only available after chemotherapy. However, phase III clinical trials have shown that PSMA-targeted therapies are
Maxone73
in
Advanced Prostate Cancer
1 month ago
Carnosine as potential initial PCa treatment
Researchers have discovered that a naturally-occurring molecule could potentially be an effective first line of treatment against prostate cancer. Nottingham Trent University (NTU) scientists investigated the anti-cancer properties of carnosine, which can be produced in the body and is also found
Researchers have discovered that a naturally-occurring molecule could potentially be an effective first line of treatment against prostate cancer. Nottingham Trent University (NTU) scientists investigated the anti-cancer properties of carnosine, which can be produced in the body and is also found
Derf4223
in
Advanced Prostate Cancer
4 months ago
Rising PSA 1 year after RALP
I've been getting ultra sensitive PSA tests every three months. These are the last three scores: 0.015 0.017 0.026 (First PSA test after surgery was <0.1) I am worried. Frightened, actually. Margins were not clear on my surgical biopsy, though gleason was only 3+3. Two biopsies prior
I've been getting ultra sensitive PSA tests every three months. These are the last three scores: 0.015 0.017 0.026 (First PSA test after surgery was <0.1) I am worried. Frightened, actually. Margins were not clear on my surgical biopsy, though gleason was only 3+3. Two biopsies prior
SmasherOfAjumma
in
Prostate Cancer Network
5 months ago
Teva - short supply
Happy New Year everyone , Is anyone else finding it difficult to get 100mcg and 50 mcg Teva Levothyroxine ? I had a thyroidectomy 6 years ago and have been really well on this medication. I changed to Accent because independent pharmacist unable to source Teva . I was really unwell for 7 days on Accent
Happy New Year everyone , Is anyone else finding it difficult to get 100mcg and 50 mcg Teva Levothyroxine ? I had a thyroidectomy 6 years ago and have been really well on this medication. I changed to Accent because independent pharmacist unable to source Teva . I was really unwell for 7 days on Accent
CheerfulCharlie
in
Thyroid UK
5 months ago
metastatic prostate cancer
my dad has castrate resistant metastatic pc in bones- currently his psa is going up but his scans have been stable- he gets them Every three months- after Zytiga and xtandi are there still many treatments available- the scans were stable for over a year and he gets them Every three Months-
my dad has castrate resistant metastatic pc in bones- currently his psa is going up but his scans have been stable- he gets them Every three months- after Zytiga and xtandi are there still many treatments available- the scans were stable for over a year and he gets them Every three Months-
Chris52981
in
Advanced Prostate Cancer
5 months ago
Benefits of knowing your illness/condition/disease to help others as well as yourself
It’s about time I posted that a couple of months ago my husband was diagnosed with Giant Cell Arteritis. I was somewhat overwhelmed by the diagnosis having had PMR, GCA/LVV myself over the past 5 and a half years and haven’t, until now, felt ready to share his story on the forum.
It’s about time I posted that a couple of months ago my husband was diagnosed with Giant Cell Arteritis. I was somewhat overwhelmed by the diagnosis having had PMR, GCA/LVV myself over the past 5 and a half years and haven’t, until now, felt ready to share his story on the forum.
123-go
in
PMRGCAuk
7 months ago
Some good advancements today too: Advances in Engineered Macrophages - A New Frontier in Cancer Immunotherapy
"These cells act synergistically in tumour progression, invasion, metastasis, and response to immunotherapies. Consequently, cancer treatment has transitioned from a model centred solely on the cancer itself to one focused on the
tumour microenvironment
, and cancer immunotherapy has consequently
"These cells act synergistically in tumour progression, invasion, metastasis, and response to immunotherapies. Consequently, cancer treatment has transitioned from a model centred solely on the cancer itself to one focused on the
tumour microenvironment
, and cancer immunotherapy has consequently
Maxone73
in
Advanced Prostate Cancer
1 month ago
Improved Posts and Replies
Responding to ChatGPT charging $20 per month to use the advanced versions of Cancer Copilot and Clinical Trial Navigator: We found a way where you won't have to pay. Starting this month, "Advanced Prostate Cancer" will be power-charged by our AI engine…for free. We know many people have been shy about
Responding to ChatGPT charging $20 per month to use the advanced versions of Cancer Copilot and Clinical Trial Navigator: We found a way where you won't have to pay. Starting this month, "Advanced Prostate Cancer" will be power-charged by our AI engine…for free. We know many people have been shy about
Darryl
Partner
in
Advanced Prostate Cancer
1 month ago
PSMA and bladder Cancer?
I have been having various difficulties with urination and know that my bladder is messed up. I have radiation cystitis and who knows what else. I saw my urologist recently and he had little to offer, sort of said yes you are a mess and pretty much left it at that. I have had PSMA pet scans and SPECT
I have been having various difficulties with urination and know that my bladder is messed up. I have radiation cystitis and who knows what else. I saw my urologist recently and he had little to offer, sort of said yes you are a mess and pretty much left it at that. I have had PSMA pet scans and SPECT
spencoid2
in
Advanced Prostate Cancer
1 month ago
IMRT WITHOUT THE JELL
I'm scheduled for IMRT Radistion without the jell. Doc says the jell may push cancer microscopic cells away from the prostate. He said the cancer is about to protrude through the capsule and microsopic cancer cells could be out of the capsule and did not want to take a chance of putting the jell in and
I'm scheduled for IMRT Radistion without the jell. Doc says the jell may push cancer microscopic cells away from the prostate. He said the cancer is about to protrude through the capsule and microsopic cancer cells could be out of the capsule and did not want to take a chance of putting the jell in and
woppaginny
in
Advanced Prostate Cancer
2 months ago
Drugs interactions
I am on Lupron as the only current PC treatment. Testosterone is <>1% as of Dec/18. PCP is looking to get me on (very expensive , hard to get) Serostim to help me with HIV/PC wasting SE's Thoughts, please be kind as ADT makes me get upset for nothing. Thank you.
I am on Lupron as the only current PC treatment. Testosterone is <>1% as of Dec/18. PCP is looking to get me on (very expensive , hard to get) Serostim to help me with HIV/PC wasting SE's Thoughts, please be kind as ADT makes me get upset for nothing. Thank you.
Blueribbon63
in
Advanced Prostate Cancer
5 months ago
PSA after radiation and Hormone therapy prognosis
https://meetings.asco.org/abstracts-presentations/218387 I have be searching for some data on the impact of radiation and short term hormone therapy on Intermediate cancer. If anyone else has some additional data or experiences please post Background. I finishing up 25 doses of radiation to the
https://meetings.asco.org/abstracts-presentations/218387 I have be searching for some data on the impact of radiation and short term hormone therapy on Intermediate cancer. If anyone else has some additional data or experiences please post Background. I finishing up 25 doses of radiation to the
Mgtd
in
Prostate Cancer Network
5 months ago
Dutasteride and PSA dropping
I started taking dustasteride about 1 month ago because of high DHT and my PSA dropped from 10 to 5.5. I've read that you are supposed to double the PSA to get an "equivalent" non-dutasteride level of 11. Does anyone understand why we are supposed to double the PSA value when taking dutasteride?
I started taking dustasteride about 1 month ago because of high DHT and my PSA dropped from 10 to 5.5. I've read that you are supposed to double the PSA to get an "equivalent" non-dutasteride level of 11. Does anyone understand why we are supposed to double the PSA value when taking dutasteride?
janebob99
in
Prostate Cancer Network
5 months ago
CGA and urogram
Hi All good advisers. Have been on pred for CGA since July 2023, starting at 60mg. now at 12 mg with very slow taper. I am having a kidney urogram this April. I am also on metformin 3 x daily 500 mg. I have read that I should stop taking metformin before this procedure. How many days before should
Hi All good advisers. Have been on pred for CGA since July 2023, starting at 60mg. now at 12 mg with very slow taper. I am having a kidney urogram this April. I am also on metformin 3 x daily 500 mg. I have read that I should stop taking metformin before this procedure. How many days before should
Groda
in
PMRGCAuk
2 months ago
Darolutamide failing after 2 years. Any success if I switch to Xandi or Zytiga or do I need to move to Pluvicto.
Dx 2018. PSA 16. Been on Orgovyx. Started Second line (Darolutamide) two years ago when PSA started to rise. PSA rose over the [u]last 5 months[/u] from 0.021 (August) to 0.48 I had a few bone mets and several lymph nodes when dx. Trying to find other treatments since I'm running out of Standard
Dx 2018. PSA 16. Been on Orgovyx. Started Second line (Darolutamide) two years ago when PSA started to rise. PSA rose over the [u]last 5 months[/u] from 0.021 (August) to 0.48 I had a few bone mets and several lymph nodes when dx. Trying to find other treatments since I'm running out of Standard
Longterm101
in
Advanced Prostate Cancer
5 months ago
Abiraterone vs Nubeqa
I've been on Lupron only for 5 years, metastatic to bones. Generic AA would be the next cheapest step, but I notice my new Medicare drug plan shows $2,800 for a year's worth of Nubeqa. Any advantage to going with Nubeqa other than possible difference in side effects?
I've been on Lupron only for 5 years, metastatic to bones. Generic AA would be the next cheapest step, but I notice my new Medicare drug plan shows $2,800 for a year's worth of Nubeqa. Any advantage to going with Nubeqa other than possible difference in side effects?
dhccpa
in
Advanced Prostate Cancer
5 months ago
Overall Survival With [177]Lu-PSMA-617 vs Cabazitaxel in Metastatic Castration-Resistant Prostate Cancer
The Lancet Oncology TAKE-HOME MESSAGE TheraP was a phase II trial that compared the efficacy of radioligand therapy with 177Lu-PSMA-617 with that of cabazitaxel in patients with metastatic castration-resistant prostate cancer who had previously received docetaxel. After a median follow-up of 35.7 months
The Lancet Oncology TAKE-HOME MESSAGE TheraP was a phase II trial that compared the efficacy of radioligand therapy with 177Lu-PSMA-617 with that of cabazitaxel in patients with metastatic castration-resistant prostate cancer who had previously received docetaxel. After a median follow-up of 35.7 months
Magnus1964
in
Advanced Prostate Cancer
5 months ago
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