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Does this mark the beginning of castration resistance?
Hi all, I have been quietly reading all of your posts and comments in the background since my dad's diagnosis with Stage IV adenocarcinoma (Gleason 9 (4+5)) with distal bone metastases in September 2022. My dad's PSA at diagnosis was 150. He is 64. Since May 2023, dad has been on monthly Degarelix
Hi all, I have been quietly reading all of your posts and comments in the background since my dad's diagnosis with Stage IV adenocarcinoma (Gleason 9 (4+5)) with distal bone metastases in September 2022. My dad's PSA at diagnosis was 150. He is 64. Since May 2023, dad has been on monthly Degarelix
Agh-2022
in
Advanced Prostate Cancer
5 months ago
I love this sci-fi: Swimming Microrobots Deliver Cancer-fighting Drugs to Metastatic Lung Tumors in Mice
we are getting better and better… “The nanoparticles are made of tiny biodegradable polymer spheres, which are loaded with the chemotherapeutic drug doxorubicin and coated with red blood cell membranes.” https://today.ucsd.edu/story/swimming-microrobots-deliver-cancer-fighting-drugs-to-metastatic-lung-tumors-in-mice
we are getting better and better… “The nanoparticles are made of tiny biodegradable polymer spheres, which are loaded with the chemotherapeutic drug doxorubicin and coated with red blood cell membranes.” https://today.ucsd.edu/story/swimming-microrobots-deliver-cancer-fighting-drugs-to-metastatic-lung-tumors-in-mice
Maxone73
in
Fight Prostate Cancer
3 months ago
Diet for ADT
(Duplicate post from Advanced Prostate Cancer). What diet should I be following while on ADT for the next two years? Guidelines from handout sheets are contradictary and unclear. I have been on Orgovyx for almost three months, starting on February 27, 2024. My PSA has dropped from 9.2 to 1.2 to 0.9
(Duplicate post from Advanced Prostate Cancer). What diet should I be following while on ADT for the next two years? Guidelines from handout sheets are contradictary and unclear. I have been on Orgovyx for almost three months, starting on February 27, 2024. My PSA has dropped from 9.2 to 1.2 to 0.9
Worked_the_World
in
Prostate Cancer Network
5 months ago
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Please advice
My latest PSA on 6/11/24 was 1.06 up from 0.65 on 4/2/24. I have a meeting with my MO on 4/26 to discuss the next step. I was taking Opdivo immunotherapy from 2/2023 to 2/2024 for bladder cancer. so far my bladder cancer is in check so now I can focus on my PCA. Should I get a PSMA pet? is it time to
My latest PSA on 6/11/24 was 1.06 up from 0.65 on 4/2/24. I have a meeting with my MO on 4/26 to discuss the next step. I was taking Opdivo immunotherapy from 2/2023 to 2/2024 for bladder cancer. so far my bladder cancer is in check so now I can focus on my PCA. Should I get a PSMA pet? is it time to
old64horn
in
Advanced Prostate Cancer
3 months ago
Diet for duration of ADT?
What diet should I be following while on ADT for the next two years? Guidelines from handout sheets are contradictary and unclear. I have been on Orgovyx for almost three months, starting on February 27, 2024. My PSA has dropped from 9.2 to 1.2 to 0.9. My Gleason Score is 9 in six cores and 6 in one
What diet should I be following while on ADT for the next two years? Guidelines from handout sheets are contradictary and unclear. I have been on Orgovyx for almost three months, starting on February 27, 2024. My PSA has dropped from 9.2 to 1.2 to 0.9. My Gleason Score is 9 in six cores and 6 in one
Worked_the_World
in
Advanced Prostate Cancer
5 months ago
Exemestane and Afinitor
Hi everyone I just completed 1 month of Truqap. I had to stop treatment due to a cough and a horrible rash. I had to stay in the ER for 24 hours due to the rash. I am now moving on to Exemestane and Afinitor. I would so appreciate any experience that anyone has had on these 2 meds. I’m mostly interested
Hi everyone I just completed 1 month of Truqap. I had to stop treatment due to a cough and a horrible rash. I had to stay in the ER for 24 hours due to the rash. I am now moving on to Exemestane and Afinitor. I would so appreciate any experience that anyone has had on these 2 meds. I’m mostly interested
Jhshl512
in
SHARE Metastatic Breast Cancer
5 months ago
Why is oncologist not concerned about liver lesion?
So my husband has prostate cancer with mets to the bone, diagnosed 2 years ago, and he just had a CT scan done. They detected a lesion in his liver that was not there before. But the oncologist didn't even mention it? Can they tell it's not from the prostate cancer just from a CT scan?
So my husband has prostate cancer with mets to the bone, diagnosed 2 years ago, and he just had a CT scan done. They detected a lesion in his liver that was not there before. But the oncologist didn't even mention it? Can they tell it's not from the prostate cancer just from a CT scan?
Anatalya
in
Advanced Prostate Cancer
3 months ago
Are endocrinologists of any help after ADT?
After ADT, my MO told me that handling things like Prolia management won't be in her bailiwick. I didn't ask about post-ADT SE's and recovery from same. Hot flashes, low T, BMD loss, and last not least sarcopenia. What is the community's experience with how post-treatment SE's are best handled? Are
After ADT, my MO told me that handling things like Prolia management won't be in her bailiwick. I didn't ask about post-ADT SE's and recovery from same. Hot flashes, low T, BMD loss, and last not least sarcopenia. What is the community's experience with how post-treatment SE's are best handled? Are
Derf4223
in
Advanced Prostate Cancer
5 months ago
Podcast Episode with Abraham Morgentaler, MD about Testosterone and Prostate Cancer
This great podcast, "You are not broken," is by a female urologist, Dr. Kelly Casperson. She often explores misconceptions about hormones. This episode with Dr. Morgentaler takes a fascinating look at the theories about castration and prostate cancer. Spoiler alert: it may shake your confidence in the
This great podcast, "You are not broken," is by a female urologist, Dr. Kelly Casperson. She often explores misconceptions about hormones. This episode with Dr. Morgentaler takes a fascinating look at the theories about castration and prostate cancer. Spoiler alert: it may shake your confidence in the
Chris_Ali
in
Advanced Prostate Cancer
5 months ago
LaRue44
My husband has metastatic prostate cancer. We went through all the treatments including 5 pluvicto treatments. Even though his scan shows improvement in some areas it continues to spread. Maybe this is due to no meds such as Xtandi to stop the spread. I'm trying to get more information by reading people's
My husband has metastatic prostate cancer. We went through all the treatments including 5 pluvicto treatments. Even though his scan shows improvement in some areas it continues to spread. Maybe this is due to no meds such as Xtandi to stop the spread. I'm trying to get more information by reading people's
LaRue44
in
Advanced Prostate Cancer
5 months ago
Travel and Ibrance
I was diagnosed with MBC in June, 2023. I am on Ibrance and letrozole. My medical history is complicated by having had a donor stem cell transplant in 2018 for T cell lymphoma. My immune system was compromised from that but now with Ibrance I'm not sure what to expect in terms of traveling and
I was diagnosed with MBC in June, 2023. I am on Ibrance and letrozole. My medical history is complicated by having had a donor stem cell transplant in 2018 for T cell lymphoma. My immune system was compromised from that but now with Ibrance I'm not sure what to expect in terms of traveling and
Artesa
in
SHARE Metastatic Breast Cancer
6 months ago
stem cell for et?
Would stem cell transplant be an option for ET? I cannot take the Hydrea or Anagralide. Thanks for your feed back
Would stem cell transplant be an option for ET? I cannot take the Hydrea or Anagralide. Thanks for your feed back
Preacherswife
in
MPN Voice
6 months ago
Breast dimpling post Lumpectomy?
Hi there! Anyone notice breast dimpling after lumpectomy? It has been 6 months after my surgery and I’m seeing 2 distinct dimples showing in the surgery area. I’m thinking it could be from the scar tissue?
Hi there! Anyone notice breast dimpling after lumpectomy? It has been 6 months after my surgery and I’m seeing 2 distinct dimples showing in the surgery area. I’m thinking it could be from the scar tissue?
NeenJah
in
SHARE Breast Cancer Support
5 months ago
Protein discovery could help solve prostate cancer drug resistance Date:January 22, 2024 Source:Washington State University
I found this information while researching my husband's PSA rising issues. Found it interesting and want to share. Click on link to read the entire article https://www.sciencedaily.com/ Protein discovery could help solve prostate cancer drug resistance Date: January 22, 2024 Source: Washington
I found this information while researching my husband's PSA rising issues. Found it interesting and want to share. Click on link to read the entire article https://www.sciencedaily.com/ Protein discovery could help solve prostate cancer drug resistance Date: January 22, 2024 Source: Washington
MsHope
in
Advanced Prostate Cancer
5 months ago
Any enzalutamide for chemo?
Tall Allen recently posted about a trial in which taking enzalutamide during docetaxel chemotherapy might help get the PSA down. Abiraterone failed for me recently and I’m re-challenging with docetaxel. I’m based in the UK, and NHS protocol doesn’t allow this. Should I go off -piste and take enzalutimde
Tall Allen recently posted about a trial in which taking enzalutamide during docetaxel chemotherapy might help get the PSA down. Abiraterone failed for me recently and I’m re-challenging with docetaxel. I’m based in the UK, and NHS protocol doesn’t allow this. Should I go off -piste and take enzalutimde
Tonyliv
in
Advanced Prostate Cancer
5 months ago
Oh guys, this one is good for mCRPC: Biologic Drug-Device Combination Immunotherapy Shows Promise for Patients with mCRPC
Just presented at 2024 AACR and used clinically on 15 patients "Of the 13 evaluable patients, 11 experienced an objective response, with five complete responses and six partial responses). The other two evaluable patients had stable disease at the time of data analysis. Six patients experienced mild
Just presented at 2024 AACR and used clinically on 15 patients "Of the 13 evaluable patients, 11 experienced an objective response, with five complete responses and six partial responses). The other two evaluable patients had stable disease at the time of data analysis. Six patients experienced mild
Maxone73
in
Advanced Prostate Cancer
5 months ago
Glowing dye helps surgeons eradicate prostate cancer
[i]"A glowing marker dye that sticks to prostate cancer cells could help surgeons to remove them in real-time, according to a study funded by Cancer Research UK. [/i] [i]Cancer Research UK-funded scientists, based at the Nuffield Department of Surgical Sciences and the Department of Oncology, University
[i]"A glowing marker dye that sticks to prostate cancer cells could help surgeons to remove them in real-time, according to a study funded by Cancer Research UK. [/i] [i]Cancer Research UK-funded scientists, based at the Nuffield Department of Surgical Sciences and the Department of Oncology, University
Justfor_
in
Fight Prostate Cancer
3 months ago
Mums recurrence
My mum found out on Friday her cancer has recurred after 11 months. She will start 2nd line treatment of Carboplatin and Caelyx soon, 6 sessions, 1 every four weeks. Does anyone have any positive stories they can share with me to offer some hope. We are devastated!
My mum found out on Friday her cancer has recurred after 11 months. She will start 2nd line treatment of Carboplatin and Caelyx soon, 6 sessions, 1 every four weeks. Does anyone have any positive stories they can share with me to offer some hope. We are devastated!
Shorty18
in
My Ovacome
5 months ago
Nocturia
Ever since my radiotherapy and brachytherapy 2 months ago I have been suffering nocturia, sometimes being forced awake 5 times a night by a painful call and having little or no product when staggering once again to the toilet for a little dribble. I am now trying to limit the liquid I drink during the
Ever since my radiotherapy and brachytherapy 2 months ago I have been suffering nocturia, sometimes being forced awake 5 times a night by a painful call and having little or no product when staggering once again to the toilet for a little dribble. I am now trying to limit the liquid I drink during the
tunybgur
in
Advanced Prostate Cancer
5 months ago
Robotic wedge lung resection
During my pet scan a lung shadow was reported. Biopsy failed to get tissue but Drs. do not think it is from the stage 2/3 prostate cancer. They recommend a wedge resection via a daVinci mechanism to remove it. I'd like to hear from someone who has had that surgery but since it may be tangential to this
During my pet scan a lung shadow was reported. Biopsy failed to get tissue but Drs. do not think it is from the stage 2/3 prostate cancer. They recommend a wedge resection via a daVinci mechanism to remove it. I'd like to hear from someone who has had that surgery but since it may be tangential to this
Eadgbe
in
Advanced Prostate Cancer
5 months ago
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