Diet for duration of ADT?: What diet... - Advanced Prostate...

Advanced Prostate Cancer

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Diet for duration of ADT?

Worked_the_World profile image
20 Replies

What diet should I be following while on ADT for the next two years? Guidelines from handout sheets are contradictary and unclear.

I have been on Orgovyx for almost three months, starting on February 27, 2024. My PSA has dropped from 9.2 to 1.2 to 0.9. My Gleason Score is 9 in six cores and 6 in one more. I will receive implanted gold fiducials on April 12, and will start five sessions of SBRT on April 29, 2024. I am 85 years old. My cancer according to a CT and and MRI scan is contained within the prostate.

I am in excellent health, hit the gym several times a week, and exercise my mind with writing adventure novels and playing the piano.

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Worked_the_World profile image
Worked_the_World
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20 Replies
Tall_Allen profile image
Tall_Allen

It's a good idea to reduce the number of calories because ADT reduces your metabolic rate. There are no other changes in diet that have been shown to have any effect. Lots of useless retrospective and observational studies explain why you've seen conflicting advice.

Worked_the_World profile image
Worked_the_World in reply toTall_Allen

That is my instinct as well. Weight gain is a non-issue, thanks to my good metabolism. Our bodies are well equipped to adapt, given a chance.

I pay very close attention to my body and make immediate changes when something seems off.

Still_in_shock profile image
Still_in_shock in reply toWorked_the_World

Your metabolism will go down the ADT toilet!! Your body no longer has testosterone to adapt.

Start exercising to counter it.

KocoPr profile image
KocoPr

There are so many good diet options out there. Don’t use the Standard American Diet! The food pyramid is upside down.

Start by eating high quality foods like grass fed beef or butter, organic veggies, wild caught fish etc. stay out of the middle isles in grocery stores that’s where the really bad junk is. Ease up on the supplements some.

Your 85 and still healthy so I suspect you already do the things I mentioned.

Myself, the only real diet that i have tried was keto for 6 months during EBRT radiation therapy and it was amazing but difficult to maintain as i went from 185 to 140 and was losing a pound a day and couldn’t gain weight back. You just feel so energetic and satiated but you must drink electrolytes everyday or you’ll get cramps.

while i was on ADT for a year solid i took SARMs Osterine and cardarine 5mg each per day. Not standard of care.

I am still hormone sensitive and do a non SOC BAT regiment where i am presently experimenting with 1 month of testosterone propianate and one month of ADT (orgo and darolutamide) when I am doing ADT i go back on SARMS. All the best in your battle.

Nusch profile image
Nusch

There is enough evidence that a plant based diet plus fish is contributing to overall health. And your body needs to be in good condition to fight PC and all side effects.

dhccpa profile image
dhccpa

I've done the whole food plant based (WFPB) diet for almost five years, starting 7 months after beginning ADT in November 2018.

Lost 50 lbs. slowly, got off blood pressure med, cholesterol and triglycerides improved, as did glucose levels.

Mgtd profile image
Mgtd

Continue what you are doing. Sounds like it is working. As mentioned you may need to be more careful since your metabolism will take a hit.

No diet at this point is going to cure or stop the cancer. Most of the diet issues you read about are for pre cancer and to maintain your QOL.

Good luck.

Worked_the_World profile image
Worked_the_World in reply toMgtd

Delighted to hear. QOL, here I come back.

I am going on a bland diet for my upcoming SBRT to control gas and large bowel movements, and irritating urine I must cut out all the foods I enjoy, including sharp cheese, hot sauce, Mexican cuisine, and anything with flavor.

Once I have completed my five radiation treatments, I can return.

Hailwood profile image
Hailwood

I have been heavily involved with the Gym since my diagnosis 4 years ago...Jims pizzas, Jims Bakery, Jims Ice cream and Jims Bar....everything in moderation with lots of fluids, and remember beer is a fluid, and good coffee should never be refused.😃😃😃😃😃😃

j-o-h-n profile image
j-o-h-n in reply toHailwood

By Jiminy Cricket I'll buy that.................Hey Ana, do we have any of those Jimmy Dean sausages left over from this morning? (me<--- whispering to myself......"I bet she ate 'em")...............

Good Luck, Good Health and Good Humor.

j-o-h-n

Worked_the_World profile image
Worked_the_World in reply toj-o-h-n

Damn Man, I am hungry already. I smoked a pork tenderloin on my charcoal smoker yesterday. The rub Pit Happens made it incredibly delicious. Time for our friend, Jimmy.

Got to fight my wife and dog to eat them.

j-o-h-n profile image
j-o-h-n in reply toWorked_the_World

And the winner is............. tune in tomorrow folks and find out...........(sounds delicious BTW)

Good Luck, Good Health and Good Humor.

j-o-h-n

Worked_the_World profile image
Worked_the_World

Touché.

j-o-h-n profile image
j-o-h-n

85 years old............Eat what they put on your plate........ and like me, wear a bib........

Good Luck, Good Health and Good Humor.

j-o-h-n

Worked_the_World profile image
Worked_the_World in reply toj-o-h-n

I wish I could get away with a bib. However, . . ., I stumbled over my sleeping German Shepherd Dog several years ago and broke both bones in my right forearm. The Doc mended them with metal plates. My wrist does not rotate too well and I have to hover over my food to catch the droppings. My dog cleans the floor.

It is reassuring to realize that age brings privileges. So food drips a bit, well, so be it. I will lick my shirt off later. I eat the plate the first time around. Life is good.

Check back tomorrow, April 12, after the Doc punches gold markers into my prostate. It will be through the rectum so I will not have external scars. Don't tell anyone that I have 24k gold inserts.

They might get ideas and I don't want them investigating down there.

j-o-h-n profile image
j-o-h-n in reply toWorked_the_World

So that means if I want to steal the gold it won't be called a hold up... it will be a Hole up.....

So you eat the way I used to when I was in the joint............. with metal plates eh.....

p.s. My wife and I fight over dibs on licking my shirt...........

Good Luck, Good Health and Good Humor.

j-o-h-n

Sagewiz profile image
Sagewiz

Most of the reading I have done recommend the Mediterranean diet. Low animal fats, almost no red meat. high protein form chicken, fish and vegetable sources. No processed foods (sausage, ham, bacon, Fast-foods, anything that comes ready to eat from a wrapper, box or bag). High intake of fresh vegetables. "Eat the rainbow" - lots of different colors and intensely colored foods (berries, purple yams, carrots of all colors, etc.) No Alcohol or added or processed sugars. Dairy is questionable, as is soy. Probiotics in many forms, is advised. (pickled vegetables, Yogurt, Kefir, Kombucha, etc.) I am also taking Pectosol modified fruit pectin, medicinal mushroom powders, chlorophyll caps, and a few other supplements recommended by a couple of naturopaths. Pumpkin seeds and pumpkin seed oil are supposed to be great for prostate health.

This is what I have learned and am implementing as best I can.

cancerfox profile image
cancerfox

T_A is right. You probably will want to cut back on caloric intake somewhat while also monitoring your weight. I continued to exercise regularly during ADT but ate the same as before and I put on 20 pounds over the course of a year before I realized what was happening. You don't need drastic diet changes, but maybe do things like skipping bread or rolls with your meals, eating a lighter lunch, reduce portions a little, etc. A quick calculation for my case would indicate that I should have cut back by about 200 calories a day to compensate for the metabolism drop caused by ADT, or increased my exercise routine to burn this amount of calories. 🦊

OCKent profile image
OCKent

I’ve been following the link below. Healthy eating is never bad. Whether it makes a difference or not I don’t know but it helps my wife have something she feels like she can control. We still find plenty of ways to treat ourselves but generally try to stick to the following

urology.ucsf.edu/sites/urol...

Graham49 profile image
Graham49

Here are some of the latest research studies:

Plant-based diet associated with better quality of life in prostate cancer survivors

Stacy Loeb MD, MSc, PhD (Hon), Qi Hua MSc, Scott R. Bauer MD, ScM, Stacey A. Kenfield ScM ScD, Alicia K. Morgans MD, MPH, June M. Chan ScD, Erin L. Van Blarigan ScM, ScD … See all authors

First published: 13 February 2024

doi.org/10.1002/cncr.

“Conclusion

This prospective study provides supportive evidence that greater consumption of healthful plant-based foods is associated with modestly higher scores in quality-of-life domains among patients with prostate cancer.”

————————————

High-fat diet (HFD) promotes prostate cancer metastasis via RPS27

doi.org/10.1186/s40170-024-...

Published: 16 February 2024

“Conclusion

Our findings indicate that HFD increases the risk of PCa metastasis by elevating RPS27 expression and, subsequently, the expression of genes involved in PRAD progression. Therefore, RPS27 may serve as a novel target for the diagnosis and treatment of metastatic PCa.”

————————————

Biological role of fructose in the male reproductive system: Potential implications for prostate cancer

Carolina E. Echeverría PhD, Vanessa I. Oyarzún BS, Andrés López-Cortés PhD, Jorge Cancino PhD, Paula C. Sotomayor PhD, Marcus D. Goncalves MD, PhD, Alejandro S. Godoy PhD

First published: 27 October 2023

doi.org/10.1002/pros.24631

“Conclusion:

The existing data suggest that restriction of fructose from the diet could be a useful therapeutic strategy for patients with PCa.”

———————————-

The effect of dietary interventions or patterns on the cardiometabolic health of individuals treated with androgen deprivation therapy for prostate cancer: A systematic review

Hattie Hester Wright a n, Meegan Anne Walker b, Suzanne Broadbent b, Corey Linton c, Jacob Joseph Keech d, Karina Tirsvad Rune e, Cindy Lynne Davis f, Michelle Morris g, Anao Zhang h, Robert Usher Newton i j, Skye Marshall k l m

doi.org/10.1016/j.maturitas...

“Highlights

This systematic review found that the effect of diet on cardiometabolic outcomes was inconsistent in individuals treated with androgen deprivation therapy for prostate cancer.

A healthy Western-style diet and exercise intervention improved blood pressure.

Diet with or without exercise may moderate the risk of cardiovascular disease in people treated with androgen deprivation therapy.

Well-designed dietary interventions targeting cardiometabolic outcomes are needed.”

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