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Experiences with
Prostate-specific antigen (PSA)
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Ct scan of abdomen and pelvis and full body bone scan?
My question is this necessary since my
PSA
has been undetectable since the radiation treatment? Urologist says this is standard of care.... Thank you for any input. I appreciate it. John
My question is this necessary since my
PSA
has been undetectable since the radiation treatment? Urologist says this is standard of care.... Thank you for any input. I appreciate it. John
realtorjohn42
in
Advanced Prostate Cancer
3 months ago
PMR or PsA or both
My Rheumatologist thinks it could be PMR or
PsA
or both. Can't get a definite answer. It started overnight after a fall I had. Now I wake up really achy all over and after about an hour feel fine for 75, ha, ha. I'm only on prednisone 10mg. Any opinions would be a appreciated. Thx
My Rheumatologist thinks it could be PMR or
PsA
or both. Can't get a definite answer. It started overnight after a fall I had. Now I wake up really achy all over and after about an hour feel fine for 75, ha, ha. I'm only on prednisone 10mg. Any opinions would be a appreciated. Thx
Seal49
in
PMRGCAuk
2 months ago
PSA vs Testosterone Nadir for CRPC and Non-CRPC
This plot from Safriadi (2022) compares the mean values of
PSA
nadir versus Testosterone Nadir comparing Non-Castrate Resistant PC (Non-CRPC) to Castrate-Resistant PC (CRPC) men. For Non-CRPC men, the range of T-nadir was 2.5-49 ng/dL (mean = 21) and range for
PSA
nadir was 0.02-9 ng/mL (mean=2).
This plot from Safriadi (2022) compares the mean values of
PSA
nadir versus Testosterone Nadir comparing Non-Castrate Resistant PC (Non-CRPC) to Castrate-Resistant PC (CRPC) men. For Non-CRPC men, the range of T-nadir was 2.5-49 ng/dL (mean = 21) and range for
PSA
nadir was 0.02-9 ng/mL (mean=2).
janebob99
in
Advanced Prostate Cancer
6 months ago
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UPDATE
As you can see on my
PSA
curve my
psa
is now rising at a rate of approx 6months doubling time - and if it keeps this up my
PSA
will reach 2.0 sometime in the spring of next year. Then I expect to go onto some new chemo treatment.
As you can see on my
PSA
curve my
psa
is now rising at a rate of approx 6months doubling time - and if it keeps this up my
PSA
will reach 2.0 sometime in the spring of next year. Then I expect to go onto some new chemo treatment.
Stoneartist
in
Advanced Prostate Cancer
5 months ago
drug vacation
Who had
PSA
level come back all the way down after a drug vacation? I want to do a holiday when my Lupron wears off in a couple months.
PSA
now is .053. Been on Lupron and abi for six years.
Who had
PSA
level come back all the way down after a drug vacation? I want to do a holiday when my Lupron wears off in a couple months.
PSA
now is .053. Been on Lupron and abi for six years.
gsun
in
Advanced Prostate Cancer
6 months ago
prostate met to esophagus
PSA
was like .15 c11 neg. Higher each
PSA
. Nov to .35. I let them know each time. They wanted to wait till May. I told them about dry cough etc… they moved appointment up.
PSA
.25 there. PSMA showed spot on esophagus and one on sternum. Any info, from here, on esophagus.
PSA
was like .15 c11 neg. Higher each
PSA
. Nov to .35. I let them know each time. They wanted to wait till May. I told them about dry cough etc… they moved appointment up.
PSA
.25 there. PSMA showed spot on esophagus and one on sternum. Any info, from here, on esophagus.
Kittenlover50
in
Advanced Prostate Cancer
6 months ago
Dad's PSA now 1800..nothing works..Is this the end??
I pleaded with the Onc if we could 'think outside the box' , can we try something, anything. 2 cycles of Carboplatin brought his
PSA
down from 1500 to 1300; we were hopeful; yet after the 3rd cycle,
PSA
shot up.
I pleaded with the Onc if we could 'think outside the box' , can we try something, anything. 2 cycles of Carboplatin brought his
PSA
down from 1500 to 1300; we were hopeful; yet after the 3rd cycle,
PSA
shot up.
kikinini
in
Advanced Prostate Cancer
2 months ago
Low-T is associated with worse Prostate Cancer Specific Mortality probability after 6 months of ADT: Part III
These plots show that the probability of dying from prostate cancer (after
PSA
failure) is significantly worse for men with Low-T. Since this data is
[i]
after
failure[/i]
,
we can assume that the men in this cohort are
castrate-resistant.
These plots show that the probability of dying from prostate cancer (after
PSA
failure) is significantly worse for men with Low-T. Since this data is
[i]
after
failure[/i]
,
we can assume that the men in this cohort are
castrate-resistant.
janebob99
in
Prostate Cancer Network
5 months ago
Docetaxal chemotherapy
When my
PSA
started to rise I took abiraterone and Lupron for 3 more years and was undetectable. It started to rise again to 1.78. Then I was put on Xtandi but after a week I developed a full body rash. When that cleared they gave me Nubeqa which gave me some unpleasant side effects.
When my
PSA
started to rise I took abiraterone and Lupron for 3 more years and was undetectable. It started to rise again to 1.78. Then I was put on Xtandi but after a week I developed a full body rash. When that cleared they gave me Nubeqa which gave me some unpleasant side effects.
Gern
in
Advanced Prostate Cancer
2 months ago
Appointment with Provenge doctor
My
PSA
has been rising after six years on Lupron only. 1.92 in June, all-time lows .5 3/2021.
My
PSA
has been rising after six years on Lupron only. 1.92 in June, all-time lows .5 3/2021.
dhccpa
in
Advanced Prostate Cancer
1 month ago
Phase 1b: FOR46, a novel antibody-drug conjugate targeting a tumor-specific epitope of CD46, in combination with Enza in patients with mCRPC
"Preliminary anti-tumor activity was observed with
PSA
declines in 13/16 (81.3%) of evaluable pts, and a disease control rate (stable disease ≥ 6 months) of 41.2%" But side effects could be very hard on heavily pretreated patients https://ascopubs.org/doi/10.1200/JCO.2024.42.16_suppl.5066
"Preliminary anti-tumor activity was observed with
PSA
declines in 13/16 (81.3%) of evaluable pts, and a disease control rate (stable disease ≥ 6 months) of 41.2%" But side effects could be very hard on heavily pretreated patients https://ascopubs.org/doi/10.1200/JCO.2024.42.16_suppl.5066
Maxone73
in
Advanced Prostate Cancer
2 months ago
Treatment for low-PSA mHSPCa
The only study I can find on treatment for low-
PSA
: "Mortality Risk for Docetaxel-Treated, High-Grade Prostate Cancer With Low
PSA
Levels: A Meta-Analysis | Oncology | JAMA Network Open" | indicates that adding docetaxel to SOC for low-
PSA
patients had very good results, however this was for non-metastatic
The only study I can find on treatment for low-
PSA
: "Mortality Risk for Docetaxel-Treated, High-Grade Prostate Cancer With Low
PSA
Levels: A Meta-Analysis | Oncology | JAMA Network Open" | indicates that adding docetaxel to SOC for low-
PSA
patients had very good results, however this was for non-metastatic
Purple-Bike
in
Advanced Prostate Cancer
7 months ago
The paradigm has shifted - castrate resistance.
My T level recovered much more quickly during the last vacation than during previous vacations, and my
PSA
rose correspondingly. At 4 months my T level was 325 and my
PSA
was 4.
My T level recovered much more quickly during the last vacation than during previous vacations, and my
PSA
rose correspondingly. At 4 months my T level was 325 and my
PSA
was 4.
fireandice123
in
Advanced Prostate Cancer
6 months ago
Rising PCA - on ADT Holiday
Completed RT and 18 months on ADT (Nubeqa) paused the ADT in September after
PSA
non detectable and a fresh set of scans showed no “evidence of disease”. Continued to do bloodwork quarterly and
PSA
remained at 0. Until this week results came in at 1.2.
Completed RT and 18 months on ADT (Nubeqa) paused the ADT in September after
PSA
non detectable and a fresh set of scans showed no “evidence of disease”. Continued to do bloodwork quarterly and
PSA
remained at 0. Until this week results came in at 1.2.
Kkash
in
Advanced Prostate Cancer
5 months ago
Looking for any Info for Recent PC Diagnosis
My PC seems to be aggressive and my
PSA
is off the charts 885! I would love any positive info I can get.
My PC seems to be aggressive and my
PSA
is off the charts 885! I would love any positive info I can get.
Iber
in
Advanced Prostate Cancer
1 month ago
Is it PSA recurrence or not...
Since then his monthly
PSA
results were stable, at 0.006 3 months ago his
PSA
went from 0.006 to 0.012, then the next month to 0.029. His MO wanted to see the third month's results in order to consider salvage radiation therapy. Luckily, third month's result came in at 0.012.
Since then his monthly
PSA
results were stable, at 0.006 3 months ago his
PSA
went from 0.006 to 0.012, then the next month to 0.029. His MO wanted to see the third month's results in order to consider salvage radiation therapy. Luckily, third month's result came in at 0.012.
traveller64
in
Advanced Prostate Cancer
6 months ago
PSA Rising After PBRT
Underwent prostate bed radiation in 2022 with good results — about a year of
PSA
at .02 to .05 — past six months, .09 and now at .17 Will get a PSMA-PET, but am curious what’s next ??
Underwent prostate bed radiation in 2022 with good results — about a year of
PSA
at .02 to .05 — past six months, .09 and now at .17 Will get a PSMA-PET, but am curious what’s next ??
FLRichardson
in
Advanced Prostate Cancer
4 months ago
My Husband's update after Pluvicto.
After my husband finished the Pluvicto treatment the
psa
never went down to 0 the lowest it got was .13 from 10.88 First 3 months without treatment, his
psa
began to rise.
After my husband finished the Pluvicto treatment the
psa
never went down to 0 the lowest it got was .13 from 10.88 First 3 months without treatment, his
psa
began to rise.
Chiquis
in
Advanced Prostate Cancer
1 month ago
Testosterone and adrenal glands
My
PSA
was down to 2.8 Oct 5th. I had an orchiectomy Oct 15. My
PSA
started to rise. Nov 5th
PSA
5.15. Dec 6th
PSA
7.85. Jan 11
PSA
16.23 I have had CT and bone scan early October and another set of scans early January. The January scans do not show any significant changes.
My
PSA
was down to 2.8 Oct 5th. I had an orchiectomy Oct 15. My
PSA
started to rise. Nov 5th
PSA
5.15. Dec 6th
PSA
7.85. Jan 11
PSA
16.23 I have had CT and bone scan early October and another set of scans early January. The January scans do not show any significant changes.
Eugmn
in
Advanced Prostate Cancer
7 months ago
Manuka honey does it help
I have locally advanced prostate cancer, finished treatment rt/ht 2016,
psa
at the moment 0.04,regarding diet I know whats what, but regarding Manuka honey instead of white sugar would Manuka honey be ok.
I have locally advanced prostate cancer, finished treatment rt/ht 2016,
psa
at the moment 0.04,regarding diet I know whats what, but regarding Manuka honey instead of white sugar would Manuka honey be ok.
Radars
in
Prostate Cancer Network
3 months ago
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