UPDATE

[Stoneartist]

UPDATE

Hi folks, I havnt been very active recently - mostly because things were going slowly, but well with my PCA. Ive just had my latest bloodwork which confirms a PCA increase with a doubling time of about 6 months. This is all very standard and to be expected - I am 4.3 years out from PSA of 1000 and start of SOC treatment. After the appearance of a castrate resistant tumour type I started on Xtandi which did a great job. As you can see on my PSA curve my psa is now rising at a rate of approx 6months doubling time - and if it keeps this up my PSA will reach 2.0 sometime in the spring of next year. Then I expect to go onto some new chemo treatment. I understand that I am still on a very standard PCa development with nothing to worry about (I am a born optimist)

But I feel lucky in that I still have no symptoms. The only change I am going to make is to increase my exercise regime.

Keep fighting folks!!

[Rolphs]

Really like this post. The graph illustrates your PC PSA journey so much better than a table or list. I’m following a similar trajectory, Gleason 4+5, DX 930 May 21, SOC ( palliative radiation Doxe, Xandão and Orgovix). I am Castrate Sensitive but being almost 3 years out I am dreading what comes next. I am at PSA nadir of .2. Don’t know if it will go lower but very grateful every day.

Thanks!

[Boywonder56]

good attitude....i kinda mirror your graph...closing in on dreaded 2.0

[CAMPSOUPS in reply to Boywonder56]

Hope you get on some good treatment when you need it. Or better yet hope you dont hit the 2.0.

[Neathuh1]

You’re on the right path, friend. Keep that great attitude!

[Maxone73]

I will send all you the positive energy and the prayers tonight. Fight on!

[anonymoose2]

Impressive 👍

Thanks for sharing with the group.

[wolverine11]

Fairly similar situation DX 962 PSA 3 yrs. ago Started Lupron few months later added abiraterone with Prednisone, changed to 0.5 dexa about 6 months ago when PSA began rising. Feb. 10th 2024 0.41 up from 0.21 in 3 months. Doubling time 3 months. Lowest nadir was 0.1. When I reach 2.0 PSA go for PSMA scan. Chemo probably .Dr. Kwon showed Docetaxel plus carboplatin showed PSA reduction of 50% or more in 63% of patients. 30 month survival with combo 70.7% Docetaxel alone was 38.9% for OS. I Good luck my friend

[mababa]

Jeez S-A, I'll rue the day when I need a logarithmic scale to plot my PSA. Mine has double since last May 8 to 16, when PCa was first suspected. I'm also non-symptomatic, but a biopsy and scans in October put me at 4a with lesions in nearby lymph node. I've started Orgovyx (Feb) and am awaiting an appointment to install a Barrigel shield before IMRT in May. Question: I may have missed it, but did you undergo any EBRT or are you relying strictly on chemical treatments (ADT)? Half of me is ready to cancel the IMRT and rely on intermittent ADT to slow the cancer growth. This is due primarily to SEs from RT burns to adjacent tissues (urethra and rectum), greatly degrading QOL. I'm recently retired at 72 and have many plans for travel/hiking etc. with my wife of 50 yrs. You didn't state your age, but I wonder if that makes a difference.

[Stoneartist in reply to mababa]

No radiation here - just a course of Docetaxel (chemo) accompanied by ADT (Zoladex), and xtandi to zap the outbreak of castrate resistant tumours. Seems to have done the job so far. I intend to stay on ADT and Xtandi until I have good reason to use something else 😊

[Derf4223 in reply to mababa]

I had 20 session = 60 Gy IMRT in mid 2021, and then ADT+Abi+Pred since, scheduled to end 2 years from starting, with minimal side effects to date. Have been doing 4-5-6 long woodsy walks/wk with the wife and dawg all along. Urinary inconvenience SE's have taken about a year to improve and I take Azo bladder control tabs 2x/day. I'll take IMRT SE's over RP SE risks anytime, but I know people who had RP and no issues. They worked hard to find the best urologist possible. My RO was a Mass General Brigham doctor working at the regional hospital I went to, since moved on to another state (I bet he got tired of winters here.)

[mababa in reply to Derf4223]

That sounds like a very acceptable outcome, Derf. Agree re RP. But, once the PCa is out of the “house” RP isn’t really recommended anyway, I’m told. My RO is planning on 28 hits for 70 Gy IMRT, similar order of magnitude to yours. Best wishes to you for continued success in this battle.

[j-o-h-n]

Recently I mentioned to my wife that lately you were not posting. She replied, "maybe he's stoned"....... Geez, stopped her Jello for a whole week...

p.s. Good to see ya.....

Good Luck, Good Health and Good Humor.

j-o-h-n

[Stoneartist in reply to j-o-h-n]

Ha Ha - I wish!!!