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Are Lymph nodes a filter?
Do lymph nodes simply act as a temporary filter to prevent cancer from spreading too far? I was curious about this because I have 4th stage prostate cancer, and my Lymph had swelled to the size of a golfball. When I took the ADT, my PSA went from 1000, down to 6, and all evidence of cancer disappeared
Do lymph nodes simply act as a temporary filter to prevent cancer from spreading too far? I was curious about this because I have 4th stage prostate cancer, and my Lymph had swelled to the size of a golfball. When I took the ADT, my PSA went from 1000, down to 6, and all evidence of cancer disappeared
Aldo62
in
Advanced Prostate Cancer
6 months ago
How long to Castrate Resistance: ADT+/- ARSI
Further discussion on details of EMBARK study on another HU forum bears restating here (IMO). For high risk BCR (and beyond) ADT combined with ARSI (in this case enzalutamide) is clearly superior to either monotherapy. However, development of castrate resistance between ADT + Enza vs. Enz monotherapy
Further discussion on details of EMBARK study on another HU forum bears restating here (IMO). For high risk BCR (and beyond) ADT combined with ARSI (in this case enzalutamide) is clearly superior to either monotherapy. However, development of castrate resistance between ADT + Enza vs. Enz monotherapy
MateoBeach
in
Advanced Prostate Cancer
8 months ago
bleeding after first prostap injection
I had my first prostap injection on Monday and started my tibolone along with it, I’ve been so exhausted all week, no energy, very emotional, I had some light bleeding but on Saturday (yesterday) I’ve started bleeding more and now it’s like I’m taking my period, has anyone else experienced this? I have
I had my first prostap injection on Monday and started my tibolone along with it, I’ve been so exhausted all week, no energy, very emotional, I had some light bleeding but on Saturday (yesterday) I’ve started bleeding more and now it’s like I’m taking my period, has anyone else experienced this? I have
Tootie2008
in
Endometriosis UK
2 years ago
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Any difference between 6 month lupron or 6 month elegard injection?
Hi, I’m currently on 3 month lupron injection and doing well with PSA of >0.01 and asked my doctor if there is a 6 month injection. I’ve asked twice and twice he sent a prescription for Elegard instead of Lupron. Should I stay on Lupron? Is there any difference between the two?
Hi, I’m currently on 3 month lupron injection and doing well with PSA of >0.01 and asked my doctor if there is a 6 month injection. I’ve asked twice and twice he sent a prescription for Elegard instead of Lupron. Should I stay on Lupron? Is there any difference between the two?
Lslal
in
Advanced Prostate Cancer
8 months ago
4.7 PSA
Had my levels tested a year ago which was 3.2 and just last week they were tested again which shows 4.7. Considering my age my consultant thinks it's just inflammation but has ordered a MRI to have it checked. Is 4.7 any reason to be concerned?
Had my levels tested a year ago which was 3.2 and just last week they were tested again which shows 4.7. Considering my age my consultant thinks it's just inflammation but has ordered a MRI to have it checked. Is 4.7 any reason to be concerned?
Dan9267
in
Prostate Cancer Network
8 months ago
Age and timing for Triplet therapy?
I am age 81, active and neither fit nor frail, radiated in 2021 without hormone therapy. Radiated again in 2023 for a pelvic node. In December the PSA rose to 3.78 and a PSMA-PET scan showed cancer growing in prostate, shrinking in pelvic node, and spread to one abdominal node. I started ADT with
I am age 81, active and neither fit nor frail, radiated in 2021 without hormone therapy. Radiated again in 2023 for a pelvic node. In December the PSA rose to 3.78 and a PSMA-PET scan showed cancer growing in prostate, shrinking in pelvic node, and spread to one abdominal node. I started ADT with
vintage42
in
Advanced Prostate Cancer
6 months ago
had 4 treatments of Pluvicto is not dropping PSA
My Husband has had 4 treatments of Pluvicto 6 weeks apart. The first treatment dropped my PSA by over 100 points; however, the 2nd, 3rd, and 4th PSA climbed rapidly. My question is, Should he continue the treatment if it is not working for him?? Thank you, Concerned wife.
My Husband has had 4 treatments of Pluvicto 6 weeks apart. The first treatment dropped my PSA by over 100 points; however, the 2nd, 3rd, and 4th PSA climbed rapidly. My question is, Should he continue the treatment if it is not working for him?? Thank you, Concerned wife.
Areyoukiddingme
in
Advanced Prostate Cancer
8 months ago
Has Anyone Heard that it’s More Common that Patients on Abiraterone (Zytiga) are more prone to their PC morphing into Neuroendocrine ?
I read a post today that it’s more common that patients on Abiraterone (Zytiga) are more prone to their Prostate Cancer morphing into Neuroendocrine Carcinoma? Is this true? Any other Medications that are prone to have it Morp into Neuroendocrine Carcinoma ?
I read a post today that it’s more common that patients on Abiraterone (Zytiga) are more prone to their Prostate Cancer morphing into Neuroendocrine Carcinoma? Is this true? Any other Medications that are prone to have it Morp into Neuroendocrine Carcinoma ?
Shorehousejam
in
Advanced Prostate Cancer
10 months ago
Too many vitamins ?
i was diagnosed 8 years ago with prostate cancer. I chose not to do anything until 4 months ago , when i felt in pain everywhere and went for treatment . I am now on Erleada and degarelix feeling much better and with the regular side effect of hot flashes and tireness. I took for 8 years and still
i was diagnosed 8 years ago with prostate cancer. I chose not to do anything until 4 months ago , when i felt in pain everywhere and went for treatment . I am now on Erleada and degarelix feeling much better and with the regular side effect of hot flashes and tireness. I took for 8 years and still
Raminagrobis
in
Advanced Prostate Cancer
9 months ago
Do low PSA-producing cells still rely on testosterone to grow?
Am curious to know what the folks here know about this question. If higher PSA cells are driven to near extinction by ADT, and if only low-PSA producing cells survive, are the latter still dependent on testosterone for survival? If not, what do they depend on to grow?
Am curious to know what the folks here know about this question. If higher PSA cells are driven to near extinction by ADT, and if only low-PSA producing cells survive, are the latter still dependent on testosterone for survival? If not, what do they depend on to grow?
novatimo
in
Advanced Prostate Cancer
8 months ago
After bicalutimide and a high testosterone level is pre treatment T just guess work?
Just turning to fellow travellers on our various journeys for some input/advice/ thoughts as I make a decision on how far to push to the SOC for my high risk G9, given my oncologist is saying 15 months adjuvant (I am nervous of anything less than 18 months) is enough given my co morbidities, age at 73
Just turning to fellow travellers on our various journeys for some input/advice/ thoughts as I make a decision on how far to push to the SOC for my high risk G9, given my oncologist is saying 15 months adjuvant (I am nervous of anything less than 18 months) is enough given my co morbidities, age at 73
SimMartin
in
Prostate Cancer Network
6 months ago
Any Curative Treatments after RT as Sole Primary Treatment?
I see stories about RT as a treatment after RP with BCR, but don't see much when RT has been sole treatment. (See Bio-not even any ADT). PSMA-PET is clear currently, so no target for radiation. PSA has been rising, but not officially nadir plus 2, but the old 3 rises in a row has been reached. If there
I see stories about RT as a treatment after RP with BCR, but don't see much when RT has been sole treatment. (See Bio-not even any ADT). PSMA-PET is clear currently, so no target for radiation. PSA has been rising, but not officially nadir plus 2, but the old 3 rises in a row has been reached. If there
Researcher50
in
Advanced Prostate Cancer
6 months ago
EMBARK Study: ADT vs Enzalutamide +/- ADT
Results of the EMBARK study was published this week (10/19/23) in NEJM. It compared high risk BCR PCa treated in 3 groups: Lupron ADT alone. Enzalutamide plus ADT. And Enzalutamide monotherapy. 5 year follow up for metastasis free survival. Results below. Interesting that Enza monotherapy (No ADT) was
Results of the EMBARK study was published this week (10/19/23) in NEJM. It compared high risk BCR PCa treated in 3 groups: Lupron ADT alone. Enzalutamide plus ADT. And Enzalutamide monotherapy. 5 year follow up for metastasis free survival. Results below. Interesting that Enza monotherapy (No ADT) was
MateoBeach
in
Advanced Prostate Cancer
8 months ago
EMBARK Study: Enzalutamide +/- ADT
Results of the EMBARK study was published this week (10/19/23) in NEJM. It compared high risk BCR PCa treated in 3 groups: Lupron ADT alone. Enzalutamide plus ADT. And Enzalutamide monotherapy. 5 year follow up for metastasis free survival. Results below. Interesting that Enza monotherapy (No ADT) was
Results of the EMBARK study was published this week (10/19/23) in NEJM. It compared high risk BCR PCa treated in 3 groups: Lupron ADT alone. Enzalutamide plus ADT. And Enzalutamide monotherapy. 5 year follow up for metastasis free survival. Results below. Interesting that Enza monotherapy (No ADT) was
MateoBeach
in
Fight Prostate Cancer
8 months ago
PSA SCREEN VS SYMPTOMATIC
My current PSA test is called PROSTATE SPC AG, SCREEN. My previous PSA test from the same lab was called PROSTATE SPC AG, SYMPTOMATIC. Both labs were off the same order from my MO. Whats the difference?
My current PSA test is called PROSTATE SPC AG, SCREEN. My previous PSA test from the same lab was called PROSTATE SPC AG, SYMPTOMATIC. Both labs were off the same order from my MO. Whats the difference?
6357axbz
in
Advanced Prostate Cancer
9 months ago
Questions about protocol changes regarding ADT from 2nd opinion.
I was diagnosed with PC about 2 months ago. I received a 2nd opinion from John's Hopkins today and all cores had a different (slightly lower) Gleason scores than my local testing gave. However I do have the evidence of adenocarcinoma in the prostate and am starting on this road through RT (with an OAR
I was diagnosed with PC about 2 months ago. I received a 2nd opinion from John's Hopkins today and all cores had a different (slightly lower) Gleason scores than my local testing gave. However I do have the evidence of adenocarcinoma in the prostate and am starting on this road through RT (with an OAR
Eadgbe
in
Prostate Cancer Network
10 months ago
How bad are these PSMA Pet Scan Results?
My second post. Just got my PSMA results back. 48 years old. PSA is 100. 12 Biopsies all show cancer. Mostly 4+3's two of them 4+4's.What do you think ? My appointment with MO is not till Wednesday. What do think he will offer as treatment method ? I'm just worried and concerned.
My second post. Just got my PSMA results back. 48 years old. PSA is 100. 12 Biopsies all show cancer. Mostly 4+3's two of them 4+4's.What do you think ? My appointment with MO is not till Wednesday. What do think he will offer as treatment method ? I'm just worried and concerned.
hiker75
in
Advanced Prostate Cancer
6 months ago
Would I be on thin ice if I tried adaptive ADT this soon?
After 6 weeks on Lupron and 9 days on abiraterone, my PSA was .1, and my testosterone was <1. This is within the criteria being used to start people on adaptive in this MCSPC Moffitt study with Jingsong Yang - (he says I can just follow the protocol without being in the study)https://pubmed.ncbi.nlm.nih.gov
After 6 weeks on Lupron and 9 days on abiraterone, my PSA was .1, and my testosterone was <1. This is within the criteria being used to start people on adaptive in this MCSPC Moffitt study with Jingsong Yang - (he says I can just follow the protocol without being in the study)https://pubmed.ncbi.nlm.nih.gov
jackwfrench
in
Advanced Prostate Cancer
8 months ago
Sleep while taking Xtandi and Adt
Hello everyone, I am sure that this has been discussed on here before, I was unable to find any post to answer my question . I am taking Xtandi ( aprox 16 months) Lupron, I had chemo. My latest PSA was less then <0.01. It has been there for over a year now. ( See my profile for my journey.) My
Hello everyone, I am sure that this has been discussed on here before, I was unable to find any post to answer my question . I am taking Xtandi ( aprox 16 months) Lupron, I had chemo. My latest PSA was less then <0.01. It has been there for over a year now. ( See my profile for my journey.) My
JD-guy
in
Advanced Prostate Cancer
8 months ago
Enhancing my urinating experience?
Guys, Several weeks ago I started experiencing slow and weak urine stream for first time since diagnosis almost 6 years ago. This, coupled with rise in PSA, triggered my oncologist to order both MRI and PSMA scan. Would appear things are progressing and got referrals to radiation oncologist and urologist
Guys, Several weeks ago I started experiencing slow and weak urine stream for first time since diagnosis almost 6 years ago. This, coupled with rise in PSA, triggered my oncologist to order both MRI and PSMA scan. Would appear things are progressing and got referrals to radiation oncologist and urologist
3putt
in
Advanced Prostate Cancer
7 months ago
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