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Dad with Stage 4 PCa - Need some words of wisdom...again please!
Hi everyone. Just got back from appointment with Dad's oncologist. To keep you up to speed - 3 months ago, his ADT injections stopped working and his PSA started to climb up slowly. Oncologist put Dad on Enzalutamide - been on it for 6 cycles - tolerated well but his PSA has gone from 76 to 87 in one
Hi everyone. Just got back from appointment with Dad's oncologist. To keep you up to speed - 3 months ago, his ADT injections stopped working and his PSA started to climb up slowly. Oncologist put Dad on Enzalutamide - been on it for 6 cycles - tolerated well but his PSA has gone from 76 to 87 in one
kikinini
in
Advanced Prostate Cancer
8 months ago
New meta-analysis shows docetaxel benefits those having high grade/low PSA prostate cancer
Reposting with more specific title - no one had replied to Maxone73's original post. Interesting results for those with a poor-prognosis cancer. https://www.miragenews.com/docetaxel-slashes-prostate-cancer-death-in-high-1115466/
Reposting with more specific title - no one had replied to Maxone73's original post. Interesting results for those with a poor-prognosis cancer. https://www.miragenews.com/docetaxel-slashes-prostate-cancer-death-in-high-1115466/
HikerWife
in
Advanced Prostate Cancer
9 months ago
Could I try BAT to restore sensitivity to previously used antiandrogen treatments.
I failed Abiraterone and SOC doesn't allow the switch to Enzalutamide. I was reading on the use of BAT to resensitize mCRPC. Would this be a therapy that could work or is it too late now that I have failed. I know its not SOC but I am running out of choices and looking for some clarity. Its basically
I failed Abiraterone and SOC doesn't allow the switch to Enzalutamide. I was reading on the use of BAT to resensitize mCRPC. Would this be a therapy that could work or is it too late now that I have failed. I know its not SOC but I am running out of choices and looking for some clarity. Its basically
Islandboy2021
in
Advanced Prostate Cancer
10 months ago
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Vitamin supplements after 12w
Do you carry on taking multivitamins like Pregnacare for pregnancy after 12w or do you pick and choose the vitamins you like? I am 17w today and my recent batch of Pregnacare ran out, I've been taking them for years... I know you don't have to but my midwife said it contains all the good stuff so if
Do you carry on taking multivitamins like Pregnacare for pregnancy after 12w or do you pick and choose the vitamins you like? I am 17w today and my recent batch of Pregnacare ran out, I've been taking them for years... I know you don't have to but my midwife said it contains all the good stuff so if
Midsummer_daydream
in
Fertility Network UK - Pregnancy Support
1 year ago
PSA rise from initial Pluvicto treatment
I am curious if most of you that have been through Pluvicto experienced a PSA rise initially? I just finished my first injection, and did see a bit of a jump in PSA level. I had a similar experience in the SPLASH trial last year. After the first Lu177 injection, my PSA shot up quite a lot. This got
I am curious if most of you that have been through Pluvicto experienced a PSA rise initially? I just finished my first injection, and did see a bit of a jump in PSA level. I had a similar experience in the SPLASH trial last year. After the first Lu177 injection, my PSA shot up quite a lot. This got
joeguy
in
Advanced Prostate Cancer
8 months ago
Enzalutamide any advice/tips for dealing with side effects
Stage 4 PCA for last 3 years. Had 6 cycles of Chemo and then Abiraterone for 18+ months (PSA dropped to 0.2 then more recently rose to 58 in June '23 ). Abiraterone eventually stopped working and I was able to join Radium 223 trial. Completed 5 of 6 cycles of Radium 223, then elected to stop since scans
Stage 4 PCA for last 3 years. Had 6 cycles of Chemo and then Abiraterone for 18+ months (PSA dropped to 0.2 then more recently rose to 58 in June '23 ). Abiraterone eventually stopped working and I was able to join Radium 223 trial. Completed 5 of 6 cycles of Radium 223, then elected to stop since scans
Ronnie7C
in
Advanced Prostate Cancer
10 months ago
Hello again.
Diagnosed in February 2021 with a PSA of 37and prescribed a 2 year course of
Prostap
by
3
monthly injections. this had the effect of immediately lowering PSA to negligible. This was very quickly followed by a course of Aberaterone {Zytiga} which I was able to tolerate for about 10 months.
Diagnosed in February 2021 with a PSA of 37and prescribed a 2 year course of
Prostap
by
3
monthly injections. this had the effect of immediately lowering PSA to negligible. This was very quickly followed by a course of Aberaterone {Zytiga} which I was able to tolerate for about 10 months.
Hidden
in
Advanced Prostate Cancer
1 year ago
some positive facts…
just woke up in this late Italian summer day and here we go: https://www.theguardian.com/society/2023/sep/30/radiotherapy-doses-for-prostate-cancer-could-be-cut-by-three-quarters-trial-finds https://www.cancernetwork.com/view/novel-drugs-may-introduce-new-era-of-metastatic-prostate-cancer-treatment
just woke up in this late Italian summer day and here we go: https://www.theguardian.com/society/2023/sep/30/radiotherapy-doses-for-prostate-cancer-could-be-cut-by-three-quarters-trial-finds https://www.cancernetwork.com/view/novel-drugs-may-introduce-new-era-of-metastatic-prostate-cancer-treatment
Maxone73
in
Advanced Prostate Cancer
10 months ago
Prostap
Anyone currently or previously been on Prostap? Finding it pretty rough. Been on Zoladex for 15 months then straight onto Prostap. 2nd jab due in couple of weeks. Does it get better?
Anyone currently or previously been on Prostap? Finding it pretty rough. Been on Zoladex for 15 months then straight onto Prostap. 2nd jab due in couple of weeks. Does it get better?
MrsPaddingtonBear
in
Endometriosis UK
1 year ago
Orchiectomy
I have metastatic cp to the bone. I have been on Lupron Xtandi and Hi dose Vitamin C for the last 19 months my current PSA is <0.1 and has been for the last 6 months. I am 83 years old and am in reasonable good health, other than pc. I have read that having an orchiectomy would yield longer life. Also
I have metastatic cp to the bone. I have been on Lupron Xtandi and Hi dose Vitamin C for the last 19 months my current PSA is <0.1 and has been for the last 6 months. I am 83 years old and am in reasonable good health, other than pc. I have read that having an orchiectomy would yield longer life. Also
Carplake
in
Advanced Prostate Cancer
8 months ago
ONCT-534 Earns FDA Fast Track Designation in R/R Metastatic CRPC
Looks like a number of Drug companies are creating drugs that interact with the AR’s N-terminal domain and ligand-binding domain, impeding cell growth and enabling AR degradation. ONCT-534 Earns FDA Fast Track Designation in R/R Metastatic CRPC October 27, 2023 Investigators will assess
Looks like a number of Drug companies are creating drugs that interact with the AR’s N-terminal domain and ligand-binding domain, impeding cell growth and enabling AR degradation. ONCT-534 Earns FDA Fast Track Designation in R/R Metastatic CRPC October 27, 2023 Investigators will assess
Scout4answers
in
Advanced Prostate Cancer
9 months ago
Treatment going forward
Boyfriend is 73 was on AS after TRUS bx with decipher score 3.0. Bx 3+4 after downgrade from JH. Now one year later Saturation Biopsy reports 3+5=8 one core and 4+5=9 two cores between 5 and 20% pattern 5. PSA remains about 3.4. Total of 9/30 positive mostly 3+4=7 20% pattern 4. PSMA PET/CT reports
Boyfriend is 73 was on AS after TRUS bx with decipher score 3.0. Bx 3+4 after downgrade from JH. Now one year later Saturation Biopsy reports 3+5=8 one core and 4+5=9 two cores between 5 and 20% pattern 5. PSA remains about 3.4. Total of 9/30 positive mostly 3+4=7 20% pattern 4. PSMA PET/CT reports
good2go
in
Advanced Prostate Cancer
5 months ago
Coagulation markers as independent predictors of prostate cancer aggressiveness.
New study below [1]. Altered coagulation factors are an early event in PCa. Indeed, the first sign of PCa in some men may be a deep vein thrombosis [DVT. The study authors wondered if there were coagulation factors associated with aggressive disease. Only fibrinogen & D-dimer were determined
New study below [1]. Altered coagulation factors are an early event in PCa. Indeed, the first sign of PCa in some men may be a deep vein thrombosis [DVT. The study authors wondered if there were coagulation factors associated with aggressive disease. Only fibrinogen & D-dimer were determined
pca2004
in
Fight Prostate Cancer
10 months ago
Aetna appeal for Firmagon denial
My husband was diagnosed with high risk aggressive prostate cancer, Gleason 9. Plus one para rectal node positive. The doctor prescribed 2 years of ADT plus 5 weeks of IMRT. Had first 240 mg dose of firmagon on September 14 with no major side effects so far. Doctor used firmagon to avoid testosterone
My husband was diagnosed with high risk aggressive prostate cancer, Gleason 9. Plus one para rectal node positive. The doctor prescribed 2 years of ADT plus 5 weeks of IMRT. Had first 240 mg dose of firmagon on September 14 with no major side effects so far. Doctor used firmagon to avoid testosterone
Oatmeal2
in
Prostate Cancer Network
10 months ago
TRT Causing Breast Enlargement
Has anyone on this site experienced breast enlargement while on TRT? Just curious as to how common this is. Am considering it because two years after ADT. (18 months Lupron and Bicalutamide) my T level is 66, PSA .28.
Has anyone on this site experienced breast enlargement while on TRT? Just curious as to how common this is. Am considering it because two years after ADT. (18 months Lupron and Bicalutamide) my T level is 66, PSA .28.
Jack54
in
Advanced Prostate Cancer
8 months ago
Changing clinic after 1st IVF failure
Hello I just want to hear your opinion about changing clinics after a failure from the previous IVF,is it a good idea? I will have to start everything afresh with this new clinic and new doctor. My previous IVF only 2 eggs collected and didn’t make it blastocyst,my doctor said could be the issue with
Hello I just want to hear your opinion about changing clinics after a failure from the previous IVF,is it a good idea? I will have to start everything afresh with this new clinic and new doctor. My previous IVF only 2 eggs collected and didn’t make it blastocyst,my doctor said could be the issue with
KHMSJ
in
Fertility Network UK
1 year ago
secondary cancer
Has anyone been diagnosed with bone marrow cancer as well as prostate cancer? My husband is getting ready to have a bone marrow biopsy to see if that is what is going on. I have read that chemo and radiation can lead to bone cancers😖
Has anyone been diagnosed with bone marrow cancer as well as prostate cancer? My husband is getting ready to have a bone marrow biopsy to see if that is what is going on. I have read that chemo and radiation can lead to bone cancers😖
Peloton
in
Advanced Prostate Cancer
10 months ago
PMR or PsA or both
My Rheumatologist left the practice and I meet with a new one last week. He says that he is not sure I have PsA but maybe only PMR. Wants me to stop methotrexate immediately and try reducing prednisone my 1 mg a month. Currently are 12.0 mg. Happy about this nut scared too. If he is wrong, when and
My Rheumatologist left the practice and I meet with a new one last week. He says that he is not sure I have PsA but maybe only PMR. Wants me to stop methotrexate immediately and try reducing prednisone my 1 mg a month. Currently are 12.0 mg. Happy about this nut scared too. If he is wrong, when and
Seal49
in
Beyond Psoriasis
6 months ago
Fatigue after eating
Husband is getting very sleepy after all meals. His sugar is always below 100 when tested, he takes levothyroxine for low thyroid (waiting for over 2 weeks now on latest blood work and TSH results from PCP. *sigh* He's taking a statin (can't remember the name) and Tamsulosin. Current cancer treatment
Husband is getting very sleepy after all meals. His sugar is always below 100 when tested, he takes levothyroxine for low thyroid (waiting for over 2 weeks now on latest blood work and TSH results from PCP. *sigh* He's taking a statin (can't remember the name) and Tamsulosin. Current cancer treatment
Union98
in
Advanced Prostate Cancer
6 months ago
Side effects experienced once you add Zytiga to Orgovyx
My husband, age 73, is diagnosed with very high risk prostate cancer, Gleason 9, PSA 46.6 and being treated ay Mayo, Phoenix. He is almost done with 28 Proton Radiation treatments, was on Casodex a few weeks then started Orgovyx.( at least two years recommended) He is considering adding Zytiga. He
My husband, age 73, is diagnosed with very high risk prostate cancer, Gleason 9, PSA 46.6 and being treated ay Mayo, Phoenix. He is almost done with 28 Proton Radiation treatments, was on Casodex a few weeks then started Orgovyx.( at least two years recommended) He is considering adding Zytiga. He
CancerConcierge
in
Advanced Prostate Cancer
9 months ago
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