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Interferon-Alpha (IFN) Therapy Discontinuation is Feasible in MPN
Conclusion: Overall, our study demonstrates that IFN discontinuation represents a safe strategy in MPN patients who achieved CHR, and particularly in patients with a driver VAF lower than 10% at time of discontinuation. Importantly, relapsed patients did not develop IFN resistance. Our data contributes
Conclusion: Overall, our study demonstrates that IFN discontinuation represents a safe strategy in MPN patients who achieved CHR, and particularly in patients with a driver VAF lower than 10% at time of discontinuation. Importantly, relapsed patients did not develop IFN resistance. Our data contributes
Manouche
in
MPN Voice
4 years ago
Clinical trials - would you participate?
Has anyone heard of Prof. Gershom Zajicek, MD, Professor of Experimental Medicine and Cancer Research, Faculty of Medicine, Hebrew University of Jerusalem? If you have, what do you think of his statements about clinical trials where he says that a) clinical trials are designed to use participants, not
Has anyone heard of Prof. Gershom Zajicek, MD, Professor of Experimental Medicine and Cancer Research, Faculty of Medicine, Hebrew University of Jerusalem? If you have, what do you think of his statements about clinical trials where he says that a) clinical trials are designed to use participants, not
HopeForCancerCure
in
Cancer Thrivers
4 years ago
JAMA study on SOC
Not great news. I, like many of us here, blend SOC approaches with unapproved approaches. "Question: What are the available data on cancer treatment outcomes for new cancer therapies approved by the US Food and Drug Administration? Findings: In this comparative effectiveness study of 92 novel cancer
Not great news. I, like many of us here, blend SOC approaches with unapproved approaches. "Question: What are the available data on cancer treatment outcomes for new cancer therapies approved by the US Food and Drug Administration? Findings: In this comparative effectiveness study of 92 novel cancer
Hidden
in
Advanced Prostate Cancer
4 years ago
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I found this study intriguing. I signed up for it and was accepted. They are still enrolling if it's anybody's cup of tea.
Pragmatic Cyclical Lower Extremity Exercise Trial for Parkinson's Disease "The study is a randomized controlled clinical trial designed to examine the disease-altering capabilities of a 12 month aerobic exercise program for individuals with PD. A total of 250 individuals with PD will be randomized into
Pragmatic Cyclical Lower Extremity Exercise Trial for Parkinson's Disease "The study is a randomized controlled clinical trial designed to examine the disease-altering capabilities of a 12 month aerobic exercise program for individuals with PD. A total of 250 individuals with PD will be randomized into
Sane1
in
Cure Parkinson's
4 years ago
To treat or not to treat: is it acceptable to avoid active therapies in advanced prostate cancer today?
New Italian paper below [1] "Introduction: Recently, there has been a paradigm shift in the treatment of advanced prostate cancer (PCa) because the approval of a number of new agents has significantly improved overall survival. However, as PCa is a heterogeneous disease that may be more or less aggressive
New Italian paper below [1] "Introduction: Recently, there has been a paradigm shift in the treatment of advanced prostate cancer (PCa) because the approval of a number of new agents has significantly improved overall survival. However, as PCa is a heterogeneous disease that may be more or less aggressive
pjoshea13
in
Advanced Prostate Cancer
4 years ago
LUPUS UK & Idorsia Webinar - Involvement in Lupus Clinical Trials - 5pm (GMT) Thursday 10th December 2020
Hi everyone, We have another webinar coming up, thanks to the assistance of Idorsia Pharmaceuticals. Please join us at
5pm (GMT)
on
Thursday 10th December
for a discussion about taking part in lupus clinical trials. If you've ever wanted to learn more about clinical trials and how to
Hi everyone, We have another webinar coming up, thanks to the assistance of Idorsia Pharmaceuticals. Please join us at
5pm (GMT)
on
Thursday 10th December
for a discussion about taking part in lupus clinical trials. If you've ever wanted to learn more about clinical trials and how to
Paul_Howard
LUPUS UK
in
LUPUS UK
4 years ago
Lung fluid, Pleural Effusion
I’ve been on my second clinical trial for the last 4 months now. For the most part is working on the lesions on my liver, lymph nodes and some of the lung nodules. It doesn’t work against my PSA which I was told it wouldn’t when I started. Started at 33.4 and now it is at 97.3. I’ve developed fluid between
I’ve been on my second clinical trial for the last 4 months now. For the most part is working on the lesions on my liver, lymph nodes and some of the lung nodules. It doesn’t work against my PSA which I was told it wouldn’t when I started. Started at 33.4 and now it is at 97.3. I’ve developed fluid between
RalphieJr64
in
Advanced Prostate Cancer
4 years ago
HCG for Testosterone Recovery after ADT
Happy Thanksgiving Fine Gentlemen! Question... I had my last scheduled Eligard shot in early September. Originally was to be on it for 2 years as part of a clinical trial. As I’ve stated in another post, I had RP in June ‘19. 4+3 Gleason in about 2/3 of the cores in one side only. PSA 15.4 at diagnosis
Happy Thanksgiving Fine Gentlemen! Question... I had my last scheduled Eligard shot in early September. Originally was to be on it for 2 years as part of a clinical trial. As I’ve stated in another post, I had RP in June ‘19. 4+3 Gleason in about 2/3 of the cores in one side only. PSA 15.4 at diagnosis
London441
in
Advanced Prostate Cancer
4 years ago
New Innovative Vaccines Are Safe, Says Top Israeli Virologist
NOVEMBER 24, 2020 11:48 AM0 New Innovative Vaccines Are Safe, Says Top Israeli Virologist by Yafit Ovadia / CTech INTERVIEW CTech – Coronavirus has wreaked havoc on the world for most of the past year, but new vaccines developed by Pfizer, Moderna, and others may hold the answer. With Pfizer’s newest
NOVEMBER 24, 2020 11:48 AM0 New Innovative Vaccines Are Safe, Says Top Israeli Virologist by Yafit Ovadia / CTech INTERVIEW CTech – Coronavirus has wreaked havoc on the world for most of the past year, but new vaccines developed by Pfizer, Moderna, and others may hold the answer. With Pfizer’s newest
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
4 years ago
Ibrutinib: Is it best used early in treatment, or after other treatment options have failed?
#CLLSociety During ASH 2019, our own Dr. Brian Koffman interviewed Dr. Paul Barr, Associate Professor of Medicine at the Wilmot Cancer Institute, in Rochester, NY, where they discussed a new analysis of clinical trial data that looks at how effective ibrutinib is depending on when it is used in a patient
#CLLSociety During ASH 2019, our own Dr. Brian Koffman interviewed Dr. Paul Barr, Associate Professor of Medicine at the Wilmot Cancer Institute, in Rochester, NY, where they discussed a new analysis of clinical trial data that looks at how effective ibrutinib is depending on when it is used in a patient
bkoffman
CLL CURE Hero
in
CLL Support
4 years ago
Phase 2 Clinical Trial - Exenatide
I understand this trial is currently recruiting. From the UCL website: Exenatide as potential treatment to slow Multiple system Atrophy (MSA) disease progression Who: People with Multiple system Atrophy (MSA), or suspected MSA, less than 5 years from diagnosis, who are able to walk at least 10 meters
I understand this trial is currently recruiting. From the UCL website: Exenatide as potential treatment to slow Multiple system Atrophy (MSA) disease progression Who: People with Multiple system Atrophy (MSA), or suspected MSA, less than 5 years from diagnosis, who are able to walk at least 10 meters
Janeyl
in
Multiple System Atrophy Trust
4 years ago
PSA up to 112, Xofigo treatment now
Hi folks, I was diagnosed in May of 2016 with Gleason 9/10 and Mets in 3 bones. I have had Lupron, Doxcetaxal, PROSTVAC, Xtandi, Zytiga, Immuneotherapy trial, Cabazitaxel, and now Awaiting my 3rd dose of Xofigo. My PSA has rose steadily since the Xtandi failed in October of 2019, now up to 112 after
Hi folks, I was diagnosed in May of 2016 with Gleason 9/10 and Mets in 3 bones. I have had Lupron, Doxcetaxal, PROSTVAC, Xtandi, Zytiga, Immuneotherapy trial, Cabazitaxel, and now Awaiting my 3rd dose of Xofigo. My PSA has rose steadily since the Xtandi failed in October of 2019, now up to 112 after
tomtom9148
in
Advanced Prostate Cancer
4 years ago
Antibody Therapy vs Vaccine
With AstraZeneca's announcement today of positive high-level results from an interim analysis of clinical trials of their vaccine candidate AZD1222, I felt compelled to post the picture above that highlights the differences between vaccines and antibody therapy. Antibody therapy is not a vaccine
With AstraZeneca's announcement today of positive high-level results from an interim analysis of clinical trials of their vaccine candidate AZD1222, I felt compelled to post the picture above that highlights the differences between vaccines and antibody therapy. Antibody therapy is not a vaccine
gardening-girl
in
CLL Support
4 years ago
Happy Holidays
Could anyone tell me why some people do better than others? Are there many strains out there of PCa? I haven't had a PSA in like 3 months but I've had a .04 last time. I was diagnosed in mid 2012 and it's been lupron and Xtandi. I'm at NIH in a clinical trial but others I've known there have died. When
Could anyone tell me why some people do better than others? Are there many strains out there of PCa? I haven't had a PSA in like 3 months but I've had a .04 last time. I was diagnosed in mid 2012 and it's been lupron and Xtandi. I'm at NIH in a clinical trial but others I've known there have died. When
Kevinski65
in
Advanced Prostate Cancer
4 years ago
Life is truly a box of chocolates.
Just finished round 3 of chemo, carboplatin and cabataxal. Psa went down 40 points from 243 to 203 thank heaven for small favors but I will take it, tolerating pretty well except the one eye growing out of my forehead. Looking forward to bombasin clinical trial if the pandemic doesn't delay. Hopefully
Just finished round 3 of chemo, carboplatin and cabataxal. Psa went down 40 points from 243 to 203 thank heaven for small favors but I will take it, tolerating pretty well except the one eye growing out of my forehead. Looking forward to bombasin clinical trial if the pandemic doesn't delay. Hopefully
Costarica1961
in
Advanced Prostate Cancer
4 years ago
Hyperbaric oxygen therapy...
I just read about a trial of volunteers in Israel who took hyperbaric oxygen therapy (HBOT) for 90 minutes a day, 5 days a week, for 3 months, and the results were apparently nothing less than extraordinary in reversing the ageing process. I then briefly checked the internet and found that dating back
I just read about a trial of volunteers in Israel who took hyperbaric oxygen therapy (HBOT) for 90 minutes a day, 5 days a week, for 3 months, and the results were apparently nothing less than extraordinary in reversing the ageing process. I then briefly checked the internet and found that dating back
Pogee
in
CLL Support
4 years ago
Development of AstraZeneca's SARS-CoV2 spike monoclonal antibodies (AZD7442)
Thank you bennevisplace for posting about AstraZeneca's monoclonal antibody clinical trial for AZD7442! AZD7442 would likely be a safe and effective prophylactic treatment for us! Reading about the development of AZD7442 led me through several incredibly detailed highly technical publications that
Thank you bennevisplace for posting about AstraZeneca's monoclonal antibody clinical trial for AZD7442! AZD7442 would likely be a safe and effective prophylactic treatment for us! Reading about the development of AZD7442 led me through several incredibly detailed highly technical publications that
gardening-girl
in
CLL Support
4 years ago
How World's Top 4 Covid19 Vaccines compare with each other ?
How World's top Four vaccines namely Pfizer, Moderna , Astrozeneca & Sputnik compare with each other ! We must note : (1) None of the much talked about four vaccines are peer reviewed yet ! (2) How long the vaccinations could give immunity...3 months ? 6 months ? 1 year ? Or more than 1 year...not
How World's top Four vaccines namely Pfizer, Moderna , Astrozeneca & Sputnik compare with each other ! We must note : (1) None of the much talked about four vaccines are peer reviewed yet ! (2) How long the vaccinations could give immunity...3 months ? 6 months ? 1 year ? Or more than 1 year...not
namaha
Administrator
in
Diabetes India
4 years ago
UK first to trial AstraZeneca 'antibody cocktail' aimed at non-vaccine patients
I'm not recruiting for Astrazeneca, but news broke this morning that they are to start phase 3 clinical trials of a long-acting antibody combination AZD7442. This will be aimed at helping clinically vulnerable groups, including immunosuppressed, for whom the COVID vaccines may not be effective https:
I'm not recruiting for Astrazeneca, but news broke this morning that they are to start phase 3 clinical trials of a long-acting antibody combination AZD7442. This will be aimed at helping clinically vulnerable groups, including immunosuppressed, for whom the COVID vaccines may not be effective https:
bennevisplace
in
CLL Support
4 years ago
Partnering in PSP Research
If you are a caregiver or a patient with PSP living in the US and Canada - UK soon, you may want to consider checking out https://www.allstripes.com/. It will give you all your relevant medical information at the click of your mouse (your consent first) and... information on clinical trials and more
If you are a caregiver or a patient with PSP living in the US and Canada - UK soon, you may want to consider checking out https://www.allstripes.com/. It will give you all your relevant medical information at the click of your mouse (your consent first) and... information on clinical trials and more
daddyt
in
PSP Association
4 years ago
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