Interferon-Alpha (IFN) Therapy Discontinuation is Feasible in MPN

[Manouche]

Conclusion: Overall, our study demonstrates that IFN discontinuation represents a safe strategy in MPN patients who achieved CHR, and particularly in patients with a driver VAF lower than 10% at time of discontinuation. Importantly, relapsed patients did not develop IFN resistance. Our data contributes to set the frame for future clinical trials evaluating the possibility of IFN treatment holidays in good responding MPN patients.

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[light]

Hi there, thank you for this information. It is very interesting one and gives me a hope, since I am on INF Alpha for many years now. Wishing you well.

[Aneliv9 in reply to light]

May i ask you what therapeutic results have you seen from IFN therapy on your therapy?

[light in reply to Aneliv9]

I am patient with ET Jak2 + and Inteferon Peg Alpha2 is managing my platelets well. Praise the Lord.

[EleanorPV]

Thanks for sharing. I've been on Pegasys for 4 years. I'm very thankful.