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first time on here
Hi! I am a 35 year old female. I was diagnosed officially with PBC at age 25. At this point in life I had a biopsy and found out I was already stage 2-3 fibrosis. Jumping forward ten years later I am now at the last stage and officially at cirrhosis. I have many symptoms now caused by the cirrhosis.
Hi! I am a 35 year old female. I was diagnosed officially with PBC at age 25. At this point in life I had a biopsy and found out I was already stage 2-3 fibrosis. Jumping forward ten years later I am now at the last stage and officially at cirrhosis. I have many symptoms now caused by the cirrhosis.
PBC2014
in
PBC Foundation
30 days ago
Cancer Turned Aggressive?
My dad has been battling prostate cancer for 15+ years . He goes to University of Chicago. He is 74. Early 2000’s- prostate removed - not clean margins. Did no further treatment 2004 - Cancer came back. Only seen on PSA test. Watched for years until PSA finally doubled. 2007-2008- went on Lupron
My dad has been battling prostate cancer for 15+ years . He goes to University of Chicago. He is 74. Early 2000’s- prostate removed - not clean margins. Did no further treatment 2004 - Cancer came back. Only seen on PSA test. Watched for years until PSA finally doubled. 2007-2008- went on Lupron
Jshaw916
in
Advanced Prostate Cancer
1 month ago
a new platform for ADC development….no sorry, it’s DAC this time! not PCa related but hopefully soon
”Orum has granted Vertex rights to conduct research using its TPD² approach to developing degrader-antibody conjugates (DACs), next-generation versions of antibody-drug conjugates (ADCs) which use antibodies to precisely deliver small molecule targeted protein degrader payloads to cancer cells and other
”Orum has granted Vertex rights to conduct research using its TPD² approach to developing degrader-antibody conjugates (DACs), next-generation versions of antibody-drug conjugates (ADCs) which use antibodies to precisely deliver small molecule targeted protein degrader payloads to cancer cells and other
Maxone73
in
Advanced Prostate Cancer
1 month ago
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Need some positivity
I have been diagnosed with liver cirrhosis I'm April/ may I have been alcohol free for 3 months but I am having a very anxious day today about my life expectancy and was hoping to hear of some positive news or advice please
I have been diagnosed with liver cirrhosis I'm April/ may I have been alcohol free for 3 months but I am having a very anxious day today about my life expectancy and was hoping to hear of some positive news or advice please
Lifefan
in
British Liver Trust
1 month ago
High ALT and Bilirubin and worried
my ‘urgent blood’ tests have come back and I am stressed to pieces as following my ultrasound I was told I had a fatty liver. My LFTs were all normal apart from my ALT which was 45 and needed to be less than 33, and Serum Bilirubin which was 27 and should be less than 21. Both readings end of March
my ‘urgent blood’ tests have come back and I am stressed to pieces as following my ultrasound I was told I had a fatty liver. My LFTs were all normal apart from my ALT which was 45 and needed to be less than 33, and Serum Bilirubin which was 27 and should be less than 21. Both readings end of March
Owlie
in
British Liver Trust
1 month ago
ELF test
hi all, If you see my previous liver posts I’ve had varying fibroscan scores, mostly overestimated because of my BMI. Lost a ton of weight and got it down to 7.2-7.5. Had another recently after regaining most of the weight and the score is up to 10KPA. Had an ultrasound in March this year and liver
hi all, If you see my previous liver posts I’ve had varying fibroscan scores, mostly overestimated because of my BMI. Lost a ton of weight and got it down to 7.2-7.5. Had another recently after regaining most of the weight and the score is up to 10KPA. Had an ultrasound in March this year and liver
Amy190
in
British Liver Trust
1 month ago
Looking for support in supporting my husband
This community has been so informative and I truly appreciate the information I have received from so many incredible people. Thank you! This is the first time I am posting to this group. In October 2023 my husband noticed more frequent use of the bathroom. He had his PSA tested in January which was
This community has been so informative and I truly appreciate the information I have received from so many incredible people. Thank you! This is the first time I am posting to this group. In October 2023 my husband noticed more frequent use of the bathroom. He had his PSA tested in January which was
Smmac15
in
Advanced Prostate Cancer
1 month ago
CRISPR Identifies New Genes as Drivers of Prostate Cancer Metastasis
Three research groups recently independently elucidated the genetic and epigenetic mechanisms driving prostate cancer metastasis. The innovative use of CRISPR technology not only facilitated the discovery of the genes but also opened potential new avenues for targeted cancer therapies to prevent metastasis
Three research groups recently independently elucidated the genetic and epigenetic mechanisms driving prostate cancer metastasis. The innovative use of CRISPR technology not only facilitated the discovery of the genes but also opened potential new avenues for targeted cancer therapies to prevent metastasis
No_stone_unturned
in
Advanced Prostate Cancer
1 month ago
Is this decision right for me
I had a PSMA pet scan on 7/16/2024. The result shows a single tumor in my left lung measuring 8mm. My MO wants me to have the tumor radiated and monitor the PSA and its doubling time. A little background, I'm just short of 83 years old. I had prostatectomy in 2009, PSA undetectable until 2017. I had
I had a PSMA pet scan on 7/16/2024. The result shows a single tumor in my left lung measuring 8mm. My MO wants me to have the tumor radiated and monitor the PSA and its doubling time. A little background, I'm just short of 83 years old. I had prostatectomy in 2009, PSA undetectable until 2017. I had
old64horn
in
Advanced Prostate Cancer
1 month ago
Can Exercise Help People with Parkinson’s Disease? 5 Things to Know
According to a study that tracked 237 patients over a five-year period, those with early-stage Parkinson’s disease who were more active had better physical outcomes than less active people with the disease. “Higher physical activity levels were strongly associated with better functioning in activities
According to a study that tracked 237 patients over a five-year period, those with early-stage Parkinson’s disease who were more active had better physical outcomes than less active people with the disease. “Higher physical activity levels were strongly associated with better functioning in activities
Farooqji
in
Cure Parkinson's
1 month ago
There's Hope
Being a dialysis patient can have its difficulty, but when you have dual diagnosis like being a diabetic sometimes it feels like all he'll breaks through. But I decided to reach out to my medical team and I got the support I needed as well as understanding my situation. I have a plan that I and my
Being a dialysis patient can have its difficulty, but when you have dual diagnosis like being a diabetic sometimes it feels like all he'll breaks through. But I decided to reach out to my medical team and I got the support I needed as well as understanding my situation. I have a plan that I and my
Quita55
in
Kidney Dialysis
1 month ago
RUQ of abdomen
Can someone have an ache in the right upper quadrant of their abdomen without it being something seriously wring with the liver like cirrhosis? Thanks, Terry
Can someone have an ache in the right upper quadrant of their abdomen without it being something seriously wring with the liver like cirrhosis? Thanks, Terry
ToughToes
in
British Liver Trust
1 month ago
please help
hello I’ve been on here a few times now, at first it started being my TSH and T3 suggesting hyperthyroidism, I was then referred to an endocrinologist and retested and that was then fine however my cortisol was low at 220 so I had a SST yesterday and the results have come back as below which they have
hello I’ve been on here a few times now, at first it started being my TSH and T3 suggesting hyperthyroidism, I was then referred to an endocrinologist and retested and that was then fine however my cortisol was low at 220 so I had a SST yesterday and the results have come back as below which they have
Lollipop93
in
Thyroid UK
1 month ago
Considering a change of dialysis centers
So, my nephrologist just up and left. I'm sure there was more going on behind the scenes than I'm aware of, but it was so sudden for me. He was also the consulting MD at the dialysis clinic. I'm not worried about finding another nephro, though. The nephrology department I deal with is a crack team
So, my nephrologist just up and left. I'm sure there was more going on behind the scenes than I'm aware of, but it was so sudden for me. He was also the consulting MD at the dialysis clinic. I'm not worried about finding another nephro, though. The nephrology department I deal with is a crack team
PeaB4YouGo
in
Kidney Dialysis
1 month ago
Integrating Network Pharmacology, Transcriptomics to Reveal Neuroprotective of Curcumin Activate PI3K / AKT Pathway in Parkinson's Disease
A mouse study, and just an abstract, but it is pro-curcumin and so am I so I am sharing it:
Integrating Network Pharmacology, Transcriptomics to Reveal Neuroprotective of Curcumin Activate PI3K / AKT Pathway in Parkinson's Disease 2024
https://pubmed.ncbi.nlm.nih.gov/39006191/
Background:
A mouse study, and just an abstract, but it is pro-curcumin and so am I so I am sharing it:
Integrating Network Pharmacology, Transcriptomics to Reveal Neuroprotective of Curcumin Activate PI3K / AKT Pathway in Parkinson's Disease 2024
https://pubmed.ncbi.nlm.nih.gov/39006191/
Background:
Bolt_Upright
in
Cure Parkinson's
1 month ago
Stuff to Do Before Comprehensive Arthroscopic Shoulder Surgery
Hi all, I'm scheduling for aka Comprehensive Arthroscopic Shoulder Surgery (Rotator Cuff Repair, Subacromial Decompression, and Shoulder Tenotomy). Fun! I live alone. I've arranged for cleaning, for grocery and food delivery, for errand running. I will try to schedule physical therapy and gather meds
Hi all, I'm scheduling for aka Comprehensive Arthroscopic Shoulder Surgery (Rotator Cuff Repair, Subacromial Decompression, and Shoulder Tenotomy). Fun! I live alone. I've arranged for cleaning, for grocery and food delivery, for errand running. I will try to schedule physical therapy and gather meds
Jimmber
in
PMRGCAuk
1 month ago
results of nail biopsy
At the end of last week I got my results of my nail biopsies. It is no fungus, no infection and best of all no cancer. They do not know what it actually is despite using numerous tests. A very happy outcome, as all medics seen in the process suspected subungual melanoma. I can live with not knowing
At the end of last week I got my results of my nail biopsies. It is no fungus, no infection and best of all no cancer. They do not know what it actually is despite using numerous tests. A very happy outcome, as all medics seen in the process suspected subungual melanoma. I can live with not knowing
artydutch
in
MPN Voice
1 month ago
Stem Cell Therapy For Parkinson's Disease - Ozzy Osbourne experience
Ozzy Osbourne has been plagued with a number of health problems in the last several years, including a Parkinson's Disease diagnosis. On his radio show, the rock icon opened up about receiving stem cell therapy to help regulate the disease. “I’ve just come back from the doctor after having some stem
Ozzy Osbourne has been plagued with a number of health problems in the last several years, including a Parkinson's Disease diagnosis. On his radio show, the rock icon opened up about receiving stem cell therapy to help regulate the disease. “I’ve just come back from the doctor after having some stem
Farooqji
in
Cure Parkinson's
1 month ago
just diagnosed with cirrhosis
I was just diagnosed with cirrhosis 6 weeks ago. My fibroscan score was 14.1 The endoscopy , blood tests and ultrasound did not show bad results. I started getting these aches in my liver area after I had the fibroscan. Is this normal. Im afraid it started something.
I was just diagnosed with cirrhosis 6 weeks ago. My fibroscan score was 14.1 The endoscopy , blood tests and ultrasound did not show bad results. I started getting these aches in my liver area after I had the fibroscan. Is this normal. Im afraid it started something.
Maddog2024
in
British Liver Trust
1 month ago
Question
Was diagnosed with stage 4 metastatic prostate cancer with several mets to the bones and a Gleason score of 10. This was in January 2023. I have been on darolutamide and relugolix since then and also 6 rounds of docetaxol. Everything was good until recently with an increase in PSA from non detectable
Was diagnosed with stage 4 metastatic prostate cancer with several mets to the bones and a Gleason score of 10. This was in January 2023. I have been on darolutamide and relugolix since then and also 6 rounds of docetaxol. Everything was good until recently with an increase in PSA from non detectable
lovepockets
in
Advanced Prostate Cancer
1 month ago
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