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Peginterferon beta-1a
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Multi vitamins - at last some recognition
Hi everyone, I was pleased to see this today - as so many 'authorities' have repeatedly put down the use of multi vitamins as being a waste of money - here is a quite extensive study showing the opposite. I used to see a very highly acclaimed consultant who said exactly the same to me and would test
Hi everyone, I was pleased to see this today - as so many 'authorities' have repeatedly put down the use of multi vitamins as being a waste of money - here is a quite extensive study showing the opposite. I used to see a very highly acclaimed consultant who said exactly the same to me and would test
posthinking01
in
Thyroid UK
3 months ago
Pee problems
Lately my hypochondria has been in over-drive. I have incontinence. That is, when I feel like I'm done , and zip -up, I shortly see fluid has soaked into my denims. I use Myrbetriq, a drug to lessen bladder spasms. It works, that is, when I'm done I don't feel the urge to continue peeing
Lately my hypochondria has been in over-drive. I have incontinence. That is, when I feel like I'm done , and zip -up, I shortly see fluid has soaked into my denims. I use Myrbetriq, a drug to lessen bladder spasms. It works, that is, when I'm done I don't feel the urge to continue peeing
kaypeeoh
in
Cure Parkinson's
4 months ago
Need your advice please
For the last 60 years I have been a vigilant weight watcher, daily exerciser and have watched my calorie intake. When I commenced treatment for my Essential Thrombocytosis in January 2021, my weight was 53.5kg. Three years later this has ballooned to 60.3kg, despite my efforts to control any
For the last 60 years I have been a vigilant weight watcher, daily exerciser and have watched my calorie intake. When I commenced treatment for my Essential Thrombocytosis in January 2021, my weight was 53.5kg. Three years later this has ballooned to 60.3kg, despite my efforts to control any
Goosebumps52
in
MPN Voice
6 months ago
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People with high blood levels of niacin, (vitamin B3), may be more likely to have a heart attack or stroke than those with lower levels
[i]I have a confession to make: I take vitamin supplements. Why is this a confession? Well, because research has indicated for years that dietary supplements are a waste of money for most people. https://www.newscientist.com/article/2325423-vitamins-and-dietary-supplements-are-a-waste-of-money-for-most-people
[i]I have a confession to make: I take vitamin supplements. Why is this a confession? Well, because research has indicated for years that dietary supplements are a waste of money for most people. https://www.newscientist.com/article/2325423-vitamins-and-dietary-supplements-are-a-waste-of-money-for-most-people
AussieNeil
Partner
in
CLL Support
6 months ago
Effective Management of Polycythemia Vera With Ropeginterferon Alfa-2b Treatment
Discussion; The results in our study demonstrate that the new dosing regimen of 250-350-500 µg of ropeginterferon alfa-2b is well-tolerated and highly efficacious in patients suffering from PV. This dosing regimen was associated with a rapid achievement of CHR without the need for phlebotomy or erythrocyte
Discussion; The results in our study demonstrate that the new dosing regimen of 250-350-500 µg of ropeginterferon alfa-2b is well-tolerated and highly efficacious in patients suffering from PV. This dosing regimen was associated with a rapid achievement of CHR without the need for phlebotomy or erythrocyte
Manouche
in
MPN Voice
4 months ago
Peginterferon alfa-2a
Hola! I'm new to this group and newly diagnosed with essential thrombocythemia. The treatment prescribed is peginterferon alfa-2a. So far I have done one treatment and wow does it suck! I haven't seen anyone else talking about this course of treatment. Is anyone else doing this? I sure could use some
Hola! I'm new to this group and newly diagnosed with essential thrombocythemia. The treatment prescribed is peginterferon alfa-2a. So far I have done one treatment and wow does it suck! I haven't seen anyone else talking about this course of treatment. Is anyone else doing this? I sure could use some
LisaLoveTacos
in
MPN Voice
8 months ago
Peginterferon alfa 2a or Hydroxycarbamide for PV?
My consultant has said I need to start treatment for PV and has asked me to choose between them. I'd really welcome any recommendations. I am new to this site, apologies uf this has been asked before.
My consultant has said I need to start treatment for PV and has asked me to choose between them. I'd really welcome any recommendations. I am new to this site, apologies uf this has been asked before.
Lyndjs
in
MPN Voice
10 months ago
Individualized Dosing of Ropeginterferon Alfa-2b Ensures Optimal Response in Patients with Low-Risk Polycythemia Vera (PV)
Conclusions: High long-term response rates (80.4% at 24 months; 73.2% at 72 months) were achieved with ropeginterferon alfa-2b treatment in the low-risk PV population when the dose was optimized on an individual basis. No specific baseline characteristics among low-risk PV patients appear to be associated
Conclusions: High long-term response rates (80.4% at 24 months; 73.2% at 72 months) were achieved with ropeginterferon alfa-2b treatment in the low-risk PV population when the dose was optimized on an individual basis. No specific baseline characteristics among low-risk PV patients appear to be associated
Manouche
in
MPN Voice
8 months ago
beta sitosterol
Just ordered some beta sitosterol and fenbendazole. Coupling these with Ivermectin, melatonin , Lupron and abiraterone. Anyone with any success with these?
Just ordered some beta sitosterol and fenbendazole. Coupling these with Ivermectin, melatonin , Lupron and abiraterone. Anyone with any success with these?
Nowhereman9
in
Advanced Prostate Cancer
11 months ago
Driving myself Crazy,,, Genetic results
So I did the BlueHorizon genetic results posted for some reason on PA page 🤯, https://healthunlocked.com/pasoc/posts/149956199/genetic-test-results maybe not a good day for revisiting this having serious head wobble. I am confused, DIO1 rs 2235544 AA, normal not increased activity ,
So I did the BlueHorizon genetic results posted for some reason on PA page 🤯, https://healthunlocked.com/pasoc/posts/149956199/genetic-test-results maybe not a good day for revisiting this having serious head wobble. I am confused, DIO1 rs 2235544 AA, normal not increased activity ,
Polo22
in
Thyroid UK
11 months ago
Supplements - Dangerous, Essential or Useless?
Wizard recently made an interesting post on the "drive to minimize supplementation" that I wanted to respond to in-depth. The post: https://healthunlocked.com/pasoc/posts/150006558/the-drive-to-reduce-minimize-supplementation I decided a long form response would be better, thus my separate post here.
Wizard recently made an interesting post on the "drive to minimize supplementation" that I wanted to respond to in-depth. The post: https://healthunlocked.com/pasoc/posts/150006558/the-drive-to-reduce-minimize-supplementation I decided a long form response would be better, thus my separate post here.
Technoid
in
Pernicious Anaemia Society
11 months ago
3 Oct 2023 Sleep issue solved so far I think
G'day ms friends and family. Everybody great so far today? I am, I slept all night, did not wake to urinate, slept alll night and woke up at the usual time. I had a win, the medicine is called zolpidem .5mg. I am sure there are side effects but I just want to sleep so Iwill find out about it
G'day ms friends and family. Everybody great so far today? I am, I slept all night, did not wake to urinate, slept alll night and woke up at the usual time. I had a win, the medicine is called zolpidem .5mg. I am sure there are side effects but I just want to sleep so Iwill find out about it
RoyceNewton
in
My MSAA Community
11 months ago
Event-free survival in patients with polycythemia vera treated with Besremi versus best available treatment
»Normal life expectancy may be achievable in PV based on comparable overall survival in interferon-treated patients and a matched US population (p = 0.3), contrasting with shortened survival (p = 0.03) in non-interferon treated patients at the same academic center [3]. Although overall survival was
»Normal life expectancy may be achievable in PV based on comparable overall survival in interferon-treated patients and a matched US population (p = 0.3), contrasting with shortened survival (p = 0.03) in non-interferon treated patients at the same academic center [3]. Although overall survival was
Manouche
in
MPN Voice
1 year ago
Astaxanthin
Apologies for the offtopic but I thought this was an interesting anti-oxidant supplement although only preliminary research has been carried out on it as yet. It seems to have potential as a very powerful antioxidant but too much anti-oxidants can also be a bad thing (based on vitamin E and beta-carotene
Apologies for the offtopic but I thought this was an interesting anti-oxidant supplement although only preliminary research has been carried out on it as yet. It seems to have potential as a very powerful antioxidant but too much anti-oxidants can also be a bad thing (based on vitamin E and beta-carotene
Technoid
in
Pernicious Anaemia Society
1 year ago
Why do we use IFN-α vs IFN-β? Might IFN-β be preferred?
PLEGRIDY is a new molecular entity in which interferon beta-1a is pegylated to extend its half-life and prolong its exposure in the body, enabling study of a less frequent dosing schedule” https://www.fiercebiotech.com/biotech/biogen-idec-submits-application-to-fda-for-approval-of-plegridy%E2%84%A2-
peginterferon
-
beta
PLEGRIDY is a new molecular entity in which interferon beta-1a is pegylated to extend its half-life and prolong its exposure in the body, enabling study of a less frequent dosing schedule” https://www.fiercebiotech.com/biotech/biogen-idec-submits-application-to-fda-for-approval-of-plegridy%E2%84%A2-
peginterferon
-
beta
EPguy
in
MPN Voice
2 years ago
Good good news I am doing so much better
hello hello 👋 to each and every warrior fighting the good fight with whatever ails you I hope that you are all as well as your body is allowing you to be Well now have battled IBS (GP misdiagnosed as pancreatic cancer after she didn’t read the radiographers report stating no cancer detected no masses
hello hello 👋 to each and every warrior fighting the good fight with whatever ails you I hope that you are all as well as your body is allowing you to be Well now have battled IBS (GP misdiagnosed as pancreatic cancer after she didn’t read the radiographers report stating no cancer detected no masses
Arpin
in
IBS Network
1 year ago
Real world experience with Besremi in ET and PV following exposure to Pegasys.
Abstract Despite widespread use of Pegylated forms of Inteferon in the management of Myeloproliferative Neoplasms (MPN), most clinicians have experience predominantly with peginterferon alfa-2a (Pegasys). Third generation pegylated IFNα, ropeginterferon alfa-2b (ropegIFN; Besremi), was recommended
Abstract Despite widespread use of Pegylated forms of Inteferon in the management of Myeloproliferative Neoplasms (MPN), most clinicians have experience predominantly with peginterferon alfa-2a (Pegasys). Third generation pegylated IFNα, ropeginterferon alfa-2b (ropegIFN; Besremi), was recommended
Manouche
in
MPN Voice
2 years ago
Keeping Interferon refrigerated
Hi, I've recently started taking Peginterferon alfa-2a, and I keep it in my fridge because that's what the instructions say. I'm going to visit my girlfriend in Scotland a week tomorrow. My journey is going to take two days, so I'll leave home on Saturday morning, stay in a hotel halfway on Saturday
Hi, I've recently started taking Peginterferon alfa-2a, and I keep it in my fridge because that's what the instructions say. I'm going to visit my girlfriend in Scotland a week tomorrow. My journey is going to take two days, so I'll leave home on Saturday morning, stay in a hotel halfway on Saturday
little_oblivion
in
MPN Voice
2 years ago
vitamin A test results
I’d be very grateful for an opinion on my vitamin A test results from Medichecks. (My GP told me ‘We don’t test vitamin A’, (!!!?), so I got private testing, though it’s not one of the cheaper tests. ) I know conversion of beta-carotene to retinol can be an issue in hypothyroidism, and although I have
I’d be very grateful for an opinion on my vitamin A test results from Medichecks. (My GP told me ‘We don’t test vitamin A’, (!!!?), so I got private testing, though it’s not one of the cheaper tests. ) I know conversion of beta-carotene to retinol can be an issue in hypothyroidism, and although I have
bluejourney
in
Thyroid UK
2 years ago
Interferons as the First Choice of Cytoreduction in ET and PV
»Interferons are a group of cytokines with immunomodulatory properties and were the first immune therapies used in the treatment of cancers, including hematologic malignancies. Use of standard interferon alfa-2b for MPN treatment has been limited by its difficulty in administration and adverse effect
»Interferons are a group of cytokines with immunomodulatory properties and were the first immune therapies used in the treatment of cancers, including hematologic malignancies. Use of standard interferon alfa-2b for MPN treatment has been limited by its difficulty in administration and adverse effect
Manouche
in
MPN Voice
2 years ago
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