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Ketogenic diet alters the epigenetic and immune landscape of prostate cancer to overcome resistance to immune checkpoint blockade therapy.
Overall, this strikes me as too hypothetical for us to apply, but what do I know? "Overall, these findings illuminate a potential clinical path of using HDACi and optimized KD regimens to enhance ICB therapy for PCa." HDACi = histone deacetylase inhibitor [To date, four HDAC inhibitors, Vorinostat
Overall, this strikes me as too hypothetical for us to apply, but what do I know? "Overall, these findings illuminate a potential clinical path of using HDACi and optimized KD regimens to enhance ICB therapy for PCa." HDACi = histone deacetylase inhibitor [To date, four HDAC inhibitors, Vorinostat
cigafred
in
Fight Prostate Cancer
5 months ago
not PA, next steps
Hi all. I am now SI EOD and have had my iron infusion which is great. I’ve had my autoimmune blood tests back which show I don’t have an autoimmune disease or Pernicious Anaemia (results attached). I’ve been advised that means I have a gut issue which is blocking absorption, I’m keen to get this looked
Hi all. I am now SI EOD and have had my iron infusion which is great. I’ve had my autoimmune blood tests back which show I don’t have an autoimmune disease or Pernicious Anaemia (results attached). I’ve been advised that means I have a gut issue which is blocking absorption, I’m keen to get this looked
AJackson21
in
Pernicious Anaemia Society
8 months ago
I don't have a magic wand
I'm venting here.I havnt been diagnosed but suffer from other autoimmune and am waiting a lupus retest panel on Friday this week. I have positive speckled result but not titrated so an incomplete blood result. I have hashimoto, fibro, pernicious anemia and scalp psoriasis. However, had severe muscle
I'm venting here.I havnt been diagnosed but suffer from other autoimmune and am waiting a lupus retest panel on Friday this week. I have positive speckled result but not titrated so an incomplete blood result. I have hashimoto, fibro, pernicious anemia and scalp psoriasis. However, had severe muscle
Peppermints
in
LUPUS UK
8 months ago
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Can I take malaria tablets?
I have autoimmune hepatitis cirrhosis and take azathioprine. I am going to Indonesia in June. Is it possible for me to take malaria tablets with my condition? MS
I have autoimmune hepatitis cirrhosis and take azathioprine. I am going to Indonesia in June. Is it possible for me to take malaria tablets with my condition? MS
Silky1
in
British Liver Trust
8 months ago
Can I take malaria tablets?
I have autoimmune hepatitis cirrhosis and take azathioprine. I am going to Indonesia in June. Is it possible for me to take malaria tablets with my condition? MS
I have autoimmune hepatitis cirrhosis and take azathioprine. I am going to Indonesia in June. Is it possible for me to take malaria tablets with my condition? MS
Silky1
in
British Liver Trust
8 months ago
If PSA is Suppressed by Doublet ADT, Will Salvage IMRT Cause a PSA Rise?
Hello everyone, My husband is nearing completion of his extended pelvic salvage IMRT with boost to retrocaval lymph nodes. His radiation oncologist said it may take several months before the psa calms down, so he would like to see him in July. My question is that, since he is already undetectable due
Hello everyone, My husband is nearing completion of his extended pelvic salvage IMRT with boost to retrocaval lymph nodes. His radiation oncologist said it may take several months before the psa calms down, so he would like to see him in July. My question is that, since he is already undetectable due
103532
in
Advanced Prostate Cancer
5 months ago
HDR Brachytherapy after initial RT
Anyone has a success story to share on using HDR Brachytherapy 2-3 years after initial Radiation of the prostate gland in case of recurrence of cancer? Thank you for sharing your story.
Anyone has a success story to share on using HDR Brachytherapy 2-3 years after initial Radiation of the prostate gland in case of recurrence of cancer? Thank you for sharing your story.
Simonapo
in
Advanced Prostate Cancer
5 months ago
Does changes in liver always mean cancer
Hi My partner has cirrhosis and a spot on the liver which is monitored every 6 months. Following an ultrasound, more spots have now been identified and is going for an MRI and blood tests soon. I am very worried and was wondering if anyone has had a similar situation and does this always result in a
Hi My partner has cirrhosis and a spot on the liver which is monitored every 6 months. Following an ultrasound, more spots have now been identified and is going for an MRI and blood tests soon. I am very worried and was wondering if anyone has had a similar situation and does this always result in a
RainbowLover
in
British Liver Trust
5 months ago
Fibroscan – is it too early to be jubilant?
I do now feel like a fraud being here 😔 and my apologies to anybody here who feels I’ve created a storm in a teacup for myself and that I should clear the cyber waves for genuine issues. But in fairness to myself my GPs have been expressing serious concerns to me, I feel suggesting that I’m bound to
I do now feel like a fraud being here 😔 and my apologies to anybody here who feels I’ve created a storm in a teacup for myself and that I should clear the cyber waves for genuine issues. But in fairness to myself my GPs have been expressing serious concerns to me, I feel suggesting that I’m bound to
Trotter2024
in
British Liver Trust
5 months ago
hypertension stage 2 plus enlarged heart - is this linked to underactive thyroid? Help appreciated please
I’ve been on levothyroxine since about 2005. Back up to 125 mg per day after 9 months on 100mg. Tsh was 6.9 and t4 16 when last tested in December . Although I asked for t3 to be tested no results. im waiting for an echocardiogram in March to look at my heart as its enlarged. I’m taking spirometer
I’ve been on levothyroxine since about 2005. Back up to 125 mg per day after 9 months on 100mg. Tsh was 6.9 and t4 16 when last tested in December . Although I asked for t3 to be tested no results. im waiting for an echocardiogram in March to look at my heart as its enlarged. I’m taking spirometer
Mumsie22
in
Thyroid UK
8 months ago
Low Carb or even Keto why is not recommended with low thyroid - can I control prediabetes with diet ?
Help please wise, kind people. I am autoimmune underactive and gluten intolerant but also pre diabetic. As thyroid stabilising and generally fine, I am now trying to sort the Pre diabetes and take it off the back burner. I have been reading around this on and off for ages and never got out of the
Help please wise, kind people. I am autoimmune underactive and gluten intolerant but also pre diabetic. As thyroid stabilising and generally fine, I am now trying to sort the Pre diabetes and take it off the back burner. I have been reading around this on and off for ages and never got out of the
Sleepman
in
Thyroid UK
8 months ago
Docetaxel Failing
Greetings from Inverness in the beautiful Highlands of Scotland! I would like to share my journey with you and hopefully get some advice on future treatments. In December 2022 following diagnoses of advanced prostate cancer with multiple bone metastasis I started zytiga + prednisone and 6 monthly triptorelin
Greetings from Inverness in the beautiful Highlands of Scotland! I would like to share my journey with you and hopefully get some advice on future treatments. In December 2022 following diagnoses of advanced prostate cancer with multiple bone metastasis I started zytiga + prednisone and 6 monthly triptorelin
Fisherman2
in
Advanced Prostate Cancer
6 months ago
Severe cirrhosis, any hope?
My father is in hospital with severe cirrhosis. He has been drinking a litre of vodka a day for 2 years. It sounds silly but none of us knew about it. He never seemed drunk. We are beating ourselves up wishing we could have intervened sooner. We phoned his DR after finding the empty bottles and he was
My father is in hospital with severe cirrhosis. He has been drinking a litre of vodka a day for 2 years. It sounds silly but none of us knew about it. He never seemed drunk. We are beating ourselves up wishing we could have intervened sooner. We phoned his DR after finding the empty bottles and he was
Puddles0
in
British Liver Trust
6 months ago
Prednisolone for Lupus Flare
Hello Does anyone find a short course of Prednisolone help with fatigue and joint pain during a Lupus Flare? Chris5530
Hello Does anyone find a short course of Prednisolone help with fatigue and joint pain during a Lupus Flare? Chris5530
Chris5530
in
LUPUS UK
8 months ago
Appropriate Treatment
I was diagnosed with stage 4 prostate cancer PSA 29.1 which had metastatised to lymph nodes, ribs & spine after a few months on Abiraterone and Prednisone my PSA count dropped to 0.06 After 30 months my PSA started to rise at 10.2 my treatment was declared ineffective Lutetium 177 treatment was recommended
I was diagnosed with stage 4 prostate cancer PSA 29.1 which had metastatised to lymph nodes, ribs & spine after a few months on Abiraterone and Prednisone my PSA count dropped to 0.06 After 30 months my PSA started to rise at 10.2 my treatment was declared ineffective Lutetium 177 treatment was recommended
154Eleventh
in
Advanced Prostate Cancer
6 months ago
hydroxychloroquine and stuffy itchy nose with occasional bleeding.
My rheumatologist added hydroxychloroquine to my methotrexate regiment for my rheumatoid arthritis. After a few weeks on the hydroxychloroquine, my nose has become itchy and stuffed up, especially when lying down and I am having trouble sleeping. Has anyone else had this problem?
My rheumatologist added hydroxychloroquine to my methotrexate regiment for my rheumatoid arthritis. After a few weeks on the hydroxychloroquine, my nose has become itchy and stuffed up, especially when lying down and I am having trouble sleeping. Has anyone else had this problem?
Apm2626
in
NRAS
8 months ago
Ureter Restriction from Radiation Treatments?
While I don't have any symptoms (yet), a CT scan and ultrasound tests show that the lower part of my right ureter tube is very narrow and causing the kidney to swell, apparently from restricted flow of urine through the ureter. My University of Chicago Medicine urologist suspects scarring in the ureter
While I don't have any symptoms (yet), a CT scan and ultrasound tests show that the lower part of my right ureter tube is very narrow and causing the kidney to swell, apparently from restricted flow of urine through the ureter. My University of Chicago Medicine urologist suspects scarring in the ureter
Polaris1
in
Advanced Prostate Cancer
6 months ago
10th year
Ten years ago I had my Gleason 9 prostate removed. PSA was .1 for a while. It crept up over .2, and I began taking lupron. The drug brought PSA back down to >.01 for a year or so. As the level started going up again, I received whole pelvis bed radiation, moving PSA to undetectable. After a year or so
Ten years ago I had my Gleason 9 prostate removed. PSA was .1 for a while. It crept up over .2, and I began taking lupron. The drug brought PSA back down to >.01 for a year or so. As the level started going up again, I received whole pelvis bed radiation, moving PSA to undetectable. After a year or so
Jvaughan0
in
Advanced Prostate Cancer
6 months ago
Help For Pernicious Anaemia Injections Effect
I was diagnosed with Pernicious Anemia, B12 Deficiency and vitamin D Deficiency. I started B12 Injections in October 2/3 a week until a full course of ten injections were given now I'm down to one every three months. My doctor allowed me an injection between the now every three months dosages as I feel
I was diagnosed with Pernicious Anemia, B12 Deficiency and vitamin D Deficiency. I started B12 Injections in October 2/3 a week until a full course of ten injections were given now I'm down to one every three months. My doctor allowed me an injection between the now every three months dosages as I feel
So_Drained
in
Pernicious Anaemia Society
8 months ago
New to PBC and Urso
Hi, I've recently been diagnosed with PBC, seems not a definitive diagnosis but consultant wanted me to start urso as he thinks it probably is this as ALP and GGT high although biopsy not very specific result and AMA negative.I started urso last week, a bit reluctantly as diagnosis seems a bit unclear
Hi, I've recently been diagnosed with PBC, seems not a definitive diagnosis but consultant wanted me to start urso as he thinks it probably is this as ALP and GGT high although biopsy not very specific result and AMA negative.I started urso last week, a bit reluctantly as diagnosis seems a bit unclear
JustChillin68
in
PBC Foundation
10 days ago
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