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What we are up against. Parkinson's Pathology: Alpha synuclein. Lewy Body.
Image credit: [i]Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes[/i] https://www.biorxiv.org/content/10.1101/137976v5.full Numerous genetic mutations can cause Parkinson's[1]. The most potent among them are mutations that cause alterations in alpha synuclein.
Image credit: [i]Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes[/i] https://www.biorxiv.org/content/10.1101/137976v5.full Numerous genetic mutations can cause Parkinson's[1]. The most potent among them are mutations that cause alterations in alpha synuclein.
park_bear
in
Cure Parkinson's
10 months ago
Blood Results TSH Low need your help with adjusting Dosage
Hi everyone I need some help again with my blood test results please. Ive been to the Endocronologist recently and based on my blood tests TSH too low she has decreased my Thyroxine by 1 tablet a week ie 75mg. (I was taking 75mg/day 7 days). I also take this 2hours before breakfast to help absorption
Hi everyone I need some help again with my blood test results please. Ive been to the Endocronologist recently and based on my blood tests TSH too low she has decreased my Thyroxine by 1 tablet a week ie 75mg. (I was taking 75mg/day 7 days). I also take this 2hours before breakfast to help absorption
Anic
in
Thyroid UK
7 months ago
Should I be concerned about high levels of Iron
Hello everyone, Following continued hair thinning/loss I had an iron test at the end of July with the results as follows - Transferrin San 49% (16-50) comments were - Consider Haemochromatosis if >40% in females. Ferritin was 142ug/L (15-200) on the same date. My previous test at the end of April
Hello everyone, Following continued hair thinning/loss I had an iron test at the end of July with the results as follows - Transferrin San 49% (16-50) comments were - Consider Haemochromatosis if >40% in females. Ferritin was 142ug/L (15-200) on the same date. My previous test at the end of April
Piglet1956
in
Thyroid UK
10 months ago
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under active Thyroid with vitamins
I’ve been taken vitamins since October. I have had a full blood count last week all normal, my urine came back normal .I have noticed aches and pains in my upper arms, neck and shoulders.. This might sound silly just wondering if anyone experienced the same.I have got under-active thyroid should I still
I’ve been taken vitamins since October. I have had a full blood count last week all normal, my urine came back normal .I have noticed aches and pains in my upper arms, neck and shoulders.. This might sound silly just wondering if anyone experienced the same.I have got under-active thyroid should I still
Peggymae-18
in
Thyroid UK
2 years ago
Recently diagnosed -Hello!
Good evening everyone. Ive been recently diagnosed with PMR, been looking on this site prior to joining, and found it very interesting and informative. I am a 78 year old woman, until recently fit and healthy, other than having full knee replacement 10 months ago, and having a stressful couple of
Good evening everyone. Ive been recently diagnosed with PMR, been looking on this site prior to joining, and found it very interesting and informative. I am a 78 year old woman, until recently fit and healthy, other than having full knee replacement 10 months ago, and having a stressful couple of
Rrdance
in
PMRGCAuk
7 months ago
Mepacrine?? Alternative to Hydroxychoroquine
Hi everyone (ladies and men out there) ,Hope your are not too busy and rush preparing for Christmas holidays ✨. So I have a few questions a bit of run down about yesterday. Saw eye Consultant yesterday not so good news . Though there showed no toxicity in my eyes there was more thinned lining(which
Hi everyone (ladies and men out there) ,Hope your are not too busy and rush preparing for Christmas holidays ✨. So I have a few questions a bit of run down about yesterday. Saw eye Consultant yesterday not so good news . Though there showed no toxicity in my eyes there was more thinned lining(which
KnitSewPurl
in
LUPUS UK
7 months ago
Update
Well been a while since I personally posted something about my health, why ? Because to be honest it hasn't really changed. We've dropped the Tranexamic Acid tablets but kept going with the Fostamatinib tablets the consultant has tried with alternating the Romoplosim injections to 250mcg one week 500mcg
Well been a while since I personally posted something about my health, why ? Because to be honest it hasn't really changed. We've dropped the Tranexamic Acid tablets but kept going with the Fostamatinib tablets the consultant has tried with alternating the Romoplosim injections to 250mcg one week 500mcg
Mesd
in
ITP Support Association
7 months ago
vitamins what’s good to take
hello I’m new to page I’ve just been diagnosed with osteoporosis score is -2.8. I asked the nurse was this good or bad she had no idea. I’m on alendronic acid and calcium but I also take vitamin d. I tried to take magnesium as well but i stopped do you think magnesium is ok to take. I also take
hello I’m new to page I’ve just been diagnosed with osteoporosis score is -2.8. I asked the nurse was this good or bad she had no idea. I’m on alendronic acid and calcium but I also take vitamin d. I tried to take magnesium as well but i stopped do you think magnesium is ok to take. I also take
Dizzy-home-life
in
Osteoporosis Support
7 months ago
dr Chris woolams
I have locally advanced prostate cancer t3b no mo finished treatment rt/ht and now I have severe osteoporosis because my testosterone has never recovered I have had 1 infusion of zoledronic acid for my bones, and now I have been reading dr Chris woolams bio-chemist on canceractive that bishonates make
I have locally advanced prostate cancer t3b no mo finished treatment rt/ht and now I have severe osteoporosis because my testosterone has never recovered I have had 1 infusion of zoledronic acid for my bones, and now I have been reading dr Chris woolams bio-chemist on canceractive that bishonates make
Radars
in
Advanced Prostate Cancer
7 months ago
Dental work and alendronate
I need a tooth extraction after a tooth has completely collapsed and became infected. The dentist has tried root canal treatment with the hope of adding a crown but it is still infected in the gum and he says it must come out due to a sepsis risk. He sent me to my consultant for permission as I have
I need a tooth extraction after a tooth has completely collapsed and became infected. The dentist has tried root canal treatment with the hope of adding a crown but it is still infected in the gum and he says it must come out due to a sepsis risk. He sent me to my consultant for permission as I have
Pawscat11
in
PMRGCAuk
7 months ago
New Member
Hello, my son (5 y/o) was diagnosed with anxiety and dysregulated anger and aggression disorder about 1 year ago (children's mental health professional). He was then diagnosed with ADHD about 3 months ago (physiologist). I now have a clearer understanding that the ladder diagnosis has much to do with
Hello, my son (5 y/o) was diagnosed with anxiety and dysregulated anger and aggression disorder about 1 year ago (children's mental health professional). He was then diagnosed with ADHD about 3 months ago (physiologist). I now have a clearer understanding that the ladder diagnosis has much to do with
Jsunshine
in
CHADD's ADHD Parents Together
2 years ago
QoL to the World
Day 2 in Hawaii Got half moons, Pork Hash, baked Char siu Baos, and Chow mein from Royal Kitchen. Goodwill shopping Poke run at Foodland Chillin at Ala Moana Beach Bulgogi dinner for Mom from Mama Woo's BBQ https://photos.app.goo.gl/cwKvJTpPvCkTzRv98
Day 2 in Hawaii Got half moons, Pork Hash, baked Char siu Baos, and Chow mein from Royal Kitchen. Goodwill shopping Poke run at Foodland Chillin at Ala Moana Beach Bulgogi dinner for Mom from Mama Woo's BBQ https://photos.app.goo.gl/cwKvJTpPvCkTzRv98
dockam
in
Advanced Prostate Cancer
7 months ago
Dexa Scan Results
Hi, can anyone translate these test results for me please? My GP has put me on Alendronic Acid one per week, 70mg and l am taking Vitamin K2, Vitamin D but unfortunately l cannot seem to tolerate the calcium supplements that we have tried, they give me terrible stomach problems even in small doses.
Hi, can anyone translate these test results for me please? My GP has put me on Alendronic Acid one per week, 70mg and l am taking Vitamin K2, Vitamin D but unfortunately l cannot seem to tolerate the calcium supplements that we have tried, they give me terrible stomach problems even in small doses.
Legsandmore
in
PMRGCAuk
7 months ago
Ursodeoxycholic Acid (UDCA)
Anyone on here involved with the trial of Urso, a liver drug that showed so promise to treatment of PD Drug: ursodeoxycholic acid Subjects will be provided ~50mg/kg/day (based on the use of 250 and 500mg capsules) of UDCA to be divided into 3 equal daily doses and titrated up over ~2 weeks to a stable
Anyone on here involved with the trial of Urso, a liver drug that showed so promise to treatment of PD Drug: ursodeoxycholic acid Subjects will be provided ~50mg/kg/day (based on the use of 250 and 500mg capsules) of UDCA to be divided into 3 equal daily doses and titrated up over ~2 weeks to a stable
Furch
in
Cure Parkinson's
7 months ago
side effects Alendronic acid
I have had really bad neck pain for about 3 months, it is a lot worse in the night. My rheum consultant thinks it is osteoarthritis, but I haven’t had an X-ray or anything to confirm this. I was diagnosed with osteoporosis in August and started Alendronic acid in September. I was wondering if the neck
I have had really bad neck pain for about 3 months, it is a lot worse in the night. My rheum consultant thinks it is osteoarthritis, but I haven’t had an X-ray or anything to confirm this. I was diagnosed with osteoporosis in August and started Alendronic acid in September. I was wondering if the neck
Olliechops
in
NRAS
7 months ago
I think I have endometriosis
Hi,I am a 25 year-old teacher and I think I may have endometriosis. I thought I would post my story on here in the hope that somebody may have had something similar and maybe let me know how the rest of their journey to diagnosis went. I started my periods at the age of 10, they were always heavy
Hi,I am a 25 year-old teacher and I think I may have endometriosis. I thought I would post my story on here in the hope that somebody may have had something similar and maybe let me know how the rest of their journey to diagnosis went. I started my periods at the age of 10, they were always heavy
PinkButterfly25
in
Endometriosis UK
7 months ago
PMR/Prednisolone and dental implants
Hi, I’m enquiring as to whether anyone else has experienced issues with their dental implants since being diagnosed with PMR and taking Prednisolone. I’ve been having trouble with one of my dental implants for a couple of weeks and on seeing the dentist today have been told that the implant has loosened
Hi, I’m enquiring as to whether anyone else has experienced issues with their dental implants since being diagnosed with PMR and taking Prednisolone. I’ve been having trouble with one of my dental implants for a couple of weeks and on seeing the dentist today have been told that the implant has loosened
Tiggy70
in
PMRGCAuk
7 months ago
was it the wrong time to take myself off ibandronic acid?
Hello folks, feeling a bit out of my depths at the moment. I am now 5 years on prednisolone and, after discovering this wonderful forum was on a very slow tapering, got to 6.5 mgs but a bad cold followed by stressful events and I’m back to 7.5 mgs. My husband has recently been diagnosed with non-hodgkins
Hello folks, feeling a bit out of my depths at the moment. I am now 5 years on prednisolone and, after discovering this wonderful forum was on a very slow tapering, got to 6.5 mgs but a bad cold followed by stressful events and I’m back to 7.5 mgs. My husband has recently been diagnosed with non-hodgkins
allofaquandry
in
PMRGCAuk
7 months ago
Zolendroic acid after discovering compression fractures. Osteoporosis.
This is an update and a thank you really, as well as info for others. Last time I posted I was puzzled about back pain. Later after a scan revealed compression fractures I realised that the digging in the garden in July resulting in back pain which I thought was an old war wound slipped disc, was probably
This is an update and a thank you really, as well as info for others. Last time I posted I was puzzled about back pain. Later after a scan revealed compression fractures I realised that the digging in the garden in July resulting in back pain which I thought was an old war wound slipped disc, was probably
Ebiker
in
PMRGCAuk
7 months ago
Waiting for laperoscopy
Hi everyone :) I am just wondering if anyone has had similar experiences. I had heavy bleeding and pain during my periods, pain and bleeding during and after sex, painful bowel movements during my period. At one time I went travelling and asked if I could take my pill packets together and was told
Hi everyone :) I am just wondering if anyone has had similar experiences. I had heavy bleeding and pain during my periods, pain and bleeding during and after sex, painful bowel movements during my period. At one time I went travelling and asked if I could take my pill packets together and was told
LUCY001
in
Endometriosis UK
7 months ago
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