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Olaparib
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Olaparib
I have just been told by my oncologist that I will start
Olaparib
with Avastin, after scan showed progression of disease with more tumours in peritoneum. Does anyone have experience with this therapy? I have BRCA mutation in tumour but not in gene.
I have just been told by my oncologist that I will start
Olaparib
with Avastin, after scan showed progression of disease with more tumours in peritoneum. Does anyone have experience with this therapy? I have BRCA mutation in tumour but not in gene.
Hidden
in
My Ovacome
7 years ago
Olaparib Working !?
Something is causing the pains so to be sure to be sure another scan is ordered for August so then I might be able to relax.It seems
Olaparib
is doing what it's supposed to do.xxx
Something is causing the pains so to be sure to be sure another scan is ordered for August so then I might be able to relax.It seems
Olaparib
is doing what it's supposed to do.xxx
annieH1
in
OvaCare
7 years ago
Rucaparib - NICE appraisal
Dear All The National Institute for Health and Care Excellence (NICE) have contacted Ovacome regarding preparation for their appraisal of a PARP inhibitor (a drug that interferes with the cancer's DNA -
Olaparib
is a PARP inhibitor).
Dear All The National Institute for Health and Care Excellence (NICE) have contacted Ovacome regarding preparation for their appraisal of a PARP inhibitor (a drug that interferes with the cancer's DNA -
Olaparib
is a PARP inhibitor).
OvacomeSupport
Administrator
in
My Ovacome
7 years ago
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BRCA-2, etc, in CRPC.
Lynparza (
Olaparib
) is a PARP inhibitor that has had some success in cases with BRCA1/2 & ATM repair gene defects From Steve Freedland: ... we conducted "prospective whole-exome and transcriptome sequencing of bone or soft tissue tumor biopsies from a cohort of 150 mCRPC affected individuals." "... aberrations
Lynparza (
Olaparib
) is a PARP inhibitor that has had some success in cases with BRCA1/2 & ATM repair gene defects From Steve Freedland: ... we conducted "prospective whole-exome and transcriptome sequencing of bone or soft tissue tumor biopsies from a cohort of 150 mCRPC affected individuals." "... aberrations
pjoshea13
in
Advanced Prostate Cancer
7 years ago
Running out of treatment options? Thoughts?
I have done casodex, Lupron , zytiga , 3 chemo ( cabazitaxol, carboplatinum, Etoposide) and currently on
olaparib
( parp inhibitor targeted for Brca2 gene mutation which I am positive for) I don't think
olaparib
is working and now thinking about the next treatment.
I have done casodex, Lupron , zytiga , 3 chemo ( cabazitaxol, carboplatinum, Etoposide) and currently on
olaparib
( parp inhibitor targeted for Brca2 gene mutation which I am positive for) I don't think
olaparib
is working and now thinking about the next treatment.
Bceagle
in
Advanced Prostate Cancer
7 years ago
olaparib and temozolomid
After the chemo, he will be doing a clinical trial of "
olaparib
and temozolomid". Has anyone heard of this or had experience, or has known someone that has done this? I always hate the sounds of clinical trials because they sound like it's the end of the road. Any insight would be appreciated.
After the chemo, he will be doing a clinical trial of "
olaparib
and temozolomid". Has anyone heard of this or had experience, or has known someone that has done this? I always hate the sounds of clinical trials because they sound like it's the end of the road. Any insight would be appreciated.
Lesleykay21
in
Lung Cancer Support
7 years ago
Olaparib
Does anyone know if you have to be brac positive to be in
Olaparib
.
Does anyone know if you have to be brac positive to be in
Olaparib
.
marn
in
OvaCare
7 years ago
Niraparib - NICE appraisal
Dear All The National Institute for Health and Care Excellence (NICE) have contacted Ovacome regarding preparation for their appraisal of a PARP inhibitor (a drug that interferes with the cancer's DNA -
Olaparib
is a PARP inhibitor).
Dear All The National Institute for Health and Care Excellence (NICE) have contacted Ovacome regarding preparation for their appraisal of a PARP inhibitor (a drug that interferes with the cancer's DNA -
Olaparib
is a PARP inhibitor).
OvacomeSupport
Administrator
in
My Ovacome
7 years ago
OLAPARIB now on the benefit list in Australia, would like advice on this drug.
So would like to know about
Olaparib
and will ask her when I go back.
So would like to know about
Olaparib
and will ask her when I go back.
lorraine71-Australia
in
My Ovacome
7 years ago
Another three month checkup - good news
So I have been worrying that the pain in my side might have been sinister, turns out that my CA125 is fine, still below 3, bloods are all fine and
Olaparib
trial going well, 3 years 5 months in remission this time. The pains?
So I have been worrying that the pain in my side might have been sinister, turns out that my CA125 is fine, still below 3, bloods are all fine and
Olaparib
trial going well, 3 years 5 months in remission this time. The pains?
Katmal-UK
in
My Ovacome
7 years ago
56 year old making the best of things
. -3 types of Chemo , radiation and am on
Olaparib
- part inhibitor targeted for my gene mutation. Living everyday with pain patch but loving my life. Cancer has opened my eyes to more beautiful things in my life. One day at a time
. -3 types of Chemo , radiation and am on
Olaparib
- part inhibitor targeted for my gene mutation. Living everyday with pain patch but loving my life. Cancer has opened my eyes to more beautiful things in my life. One day at a time
Bceagle
in
Advanced Prostate Cancer
7 years ago
Xofigo & radiation together .
I have been on
olaparib
for 6 weeks,PSA gone way up fr 390 to 1040!!!! So will be stopping.I have moderate to severe bone pain in both hips and femurs. I want to start xofigo within the next two weeks,AND get SBRT for my hips/femurs. Can these be done concurrently ?
I have been on
olaparib
for 6 weeks,PSA gone way up fr 390 to 1040!!!! So will be stopping.I have moderate to severe bone pain in both hips and femurs. I want to start xofigo within the next two weeks,AND get SBRT for my hips/femurs. Can these be done concurrently ?
Hidden
in
Advanced Prostate Cancer
7 years ago
Chemo while low PSA
I have been diagnosed with a BRCA2 mutation, which is the reason I started with Lynparza (
Olaparib
). In addition I take daily supplements (Metformin, statin, vitamin D3 (10,000 iu), Wisconsin GinSeng and an Estradiol patch). Would doing chemo now be a 'smart' decision?
I have been diagnosed with a BRCA2 mutation, which is the reason I started with Lynparza (
Olaparib
). In addition I take daily supplements (Metformin, statin, vitamin D3 (10,000 iu), Wisconsin GinSeng and an Estradiol patch). Would doing chemo now be a 'smart' decision?
Terje
in
Advanced Prostate Cancer
7 years ago
Any new drug treatments I can ask the doctor about? Running low on options
Olaparib
seems to only be for the "lucky" BRCA positive girls, so I am hoping there's something else out there that might give us some hope. Would appreciate any help you could offer. I browse around here a lot just reading you girls' posts. I love how high spirited and positive you all are.
Olaparib
seems to only be for the "lucky" BRCA positive girls, so I am hoping there's something else out there that might give us some hope. Would appreciate any help you could offer. I browse around here a lot just reading you girls' posts. I love how high spirited and positive you all are.
Hawk86
in
My Ovacome
8 years ago
UpDate on Olaparib
Had my check up on the 15th of September. All blood results are great,CA125 is down to 10! Fatigue is a huge problem but I do rest as much as possible. UTI is a common side effect ,which I am getting a lot of. I'm on the drug since January and so far it seems to be keeping things stable. Hopefully it
Had my check up on the 15th of September. All blood results are great,CA125 is down to 10! Fatigue is a huge problem but I do rest as much as possible. UTI is a common side effect ,which I am getting a lot of. I'm on the drug since January and so far it seems to be keeping things stable. Hopefully it
annieH1
in
OvaCare
8 years ago
Update on Olaparib and chat with Health minister!
Feeling a lot better since coming out of hospital in May.My bloods have continued to rise so hopefully they will be good on Thurs when I meet Oncologist.I have more energy,went to the beach today and walked 2 miles! It was a glorious day.I no longer need sleeping tablet as I'm getting 6 hrs straight
Feeling a lot better since coming out of hospital in May.My bloods have continued to rise so hopefully they will be good on Thurs when I meet Oncologist.I have more energy,went to the beach today and walked 2 miles! It was a glorious day.I no longer need sleeping tablet as I'm getting 6 hrs straight
annieH1
in
OvaCare
8 years ago
Experience getting Foundation One to pay for Molecular Profiling
Currently I've been on
Olaparib
since October 2015 for treatment of a CDK12 mutation that is being treated that is a comparable BRCA2 mutation. If one anyone has experience with their insurance company or with Medicare it would be appreciated. Dominic Marrese Typed or transcribed from my iPhone
Currently I've been on
Olaparib
since October 2015 for treatment of a CDK12 mutation that is being treated that is a comparable BRCA2 mutation. If one anyone has experience with their insurance company or with Medicare it would be appreciated. Dominic Marrese Typed or transcribed from my iPhone
gl8_give1fordad
in
Advanced Prostate Cancer
8 years ago
Update on Olaparib
infusion of chemo to the start of the next one.I don't think the Onc was expecting the side effects our little group are experiencing,
Olaparib
is not what it says on the tin!!
infusion of chemo to the start of the next one.I don't think the Onc was expecting the side effects our little group are experiencing,
Olaparib
is not what it says on the tin!!
annieH1
in
OvaCare
8 years ago
Olaparib still working
Well back from our hol to Las Vegas, back to scan results which are still showing NED.. boy, what a relief. Hope you are all doing ok. I'll go through posts and catch up with you all. Thought you might like to see a pic from my holiday, Im only sharing it because I actually have a photo that makes me
Well back from our hol to Las Vegas, back to scan results which are still showing NED.. boy, what a relief. Hope you are all doing ok. I'll go through posts and catch up with you all. Thought you might like to see a pic from my holiday, Im only sharing it because I actually have a photo that makes me
Katmal-UK
in
My Ovacome
8 years ago
6 month update on Olaparib
I've been on
Olaparib
for 6 months. My predominant challenge has been low blood counts and back pain from compression fractures in my thoracic spine. Despite fact that
Olaparib
can cause anemia, my platelets & HmG are improving! This is very encouraging.
I've been on
Olaparib
for 6 months. My predominant challenge has been low blood counts and back pain from compression fractures in my thoracic spine. Despite fact that
Olaparib
can cause anemia, my platelets & HmG are improving! This is very encouraging.
gl8_give1fordad
in
Advanced Prostate Cancer
8 years ago
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